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Anti-Ulcer Agents definition: Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.
antiulcer drug definition: class of agents, exclusive of the antibacterial agents, used to treat ulcers in the stomach and the upper part of the small intestine.
Anti-ulcer Agent definition: Natural or synthetic Anti-ulcer Agents relieve and reduce the symptoms of ulcers in the stomach and upper small intestine, systemically and locally, by reducing gastric secretion (proton pump inhibitors), neutralizing hyperacidity (alkalinizing agents), or improving healing and protecting the mucosa (sucralfate). Recurrent gastric and duodenal ulcers caused by Helicobacter pylori infections are treated with antibiotic therapy. (NCI04)
Antifungal Agents definition: Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.
antifungal agent definition: substances that are destructive to fungi, suppress their reproduction or growth, or are effective against fungal infection.
antifungals definition: Drugs that treat infections caused by fungi.
Antifungal Agent definition: Substances that treat systemic or topical infections caused by fungi. Antifungal agents kill or inhibit the growth of fungi, by various mechanisms. Mechanisms include inhibition of fungal mitosis, impairing synthesis or binding to ergosterol, incorporation into RNA or DNA synthesis inhibition.
Antineoplastic Agents definition: Substances that inhibit or prevent the proliferation of NEOPLASMS.
antineoplastic definition: agent that inhibits or prevents the development or proliferation of neoplasms.
chemotherapeutic agent definition: A drug used to treat cancer.
chemotherapeutic agent definition: A substance that blocks the formation of neoplasms (growths that may become cancerous).
ANTINEOPLASTICS definition: NOTE: Includes hormones (AN500) which are exclusively used as antineoplastics (e.g.,tamoxifen). Excludes other hormones (HS000).
Antineoplastic Agent definition: A substance that inhibits the maturation, growth or spread of tumor cells.
Antiparasitic Agents definition: Drugs used to treat or prevent parasitic infections.
antiparasitics definition: Drugs used to treat bacterial and parasitic infections and some cancers.
ANTIPARASITICS definition: NOTE: Includes topical pediculicides (AP300).
antiparasitic agent definition: drug or agent used to treat or prevent parasitic infections.
Antiparkinson Agents definition: Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.
antiparkinson drug definition: agent used in the treatment of Parkinson's disease; the most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.
Appetite Depressants definition: Agents that are used to decrease appetite.
anorexic agent definition: class of drugs which suppress appetite, used for weight control.
Anorexiant definition: Any substance that induces loss of appetite to prevent weight gain and achieve weight loss.
Biological Availability definition: The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
Bioavailability definition: The rate and extent to which the active ingredient or active moiety is absorbed from a drug product and becomes available at the site of action. For drug products that are not intended to be absorbed into the bloodstream, bioavailability may be assessed by measurements intended to reflect the rate and extent to which the active ingredient or active moiety becomes available at the site of action (21CFR320.1).
Cardiovascular Agents definition: Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
cardiovascular agent definition: agents that effect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Central Nervous System Agents definition: A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)
centrally acting drug definition: class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
Designer Drugs definition: Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
Drug Abuse definition: Excessive use of habit forming medications.
drug abuse definition: excessive use of drugs or chemicals with associated psychological symptoms and impairment in social or occupational functioning.
Drug Abuse definition: The use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed.
Drug Adulteration definition: The addition of less desirable substance to the drug preparation.
Drug Antagonism definition: Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a specific receptor. On their own, antagonists produce no effect by themselves to a receptor, and are said to have neither intrinsic activity nor efficacy.
Drug Combinations definition: Single preparations containing two or more active agents, for the purpose of their concurrent administration as a fixed dose mixture.
Drug Compounding definition: The preparation, mixing, and assembling of a drug. (From Remington, The Science and Practice of Pharmacy, 19th ed, p1814)
Drug Contamination definition: The presence of organisms, or any foreign material that makes a drug preparation impure.
drug control definition: control of drug and narcotic use by international agreement, or by institutional systems for handling prescribed drugs; includes regulations concerned with the manufacturing, dispensing, approval, and marketing of drugs.
Drug Design definition: The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include pharmacokinetics, dosage analysis, or drug administration analysis.
Drug Hypersensitivity definition: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
drug hypersensitivity definition: immunologically mediated adverse reactions to medicinal substances used legally or illegally.
Drug Allergy definition:

An allergy to a pharmaceutical product.

chemotherapy definition: application of the beneficial effects of drugs to control or cure diseases or abnormal states in living organisms or tissues.
Drug therapy definition:

The introduction of a drug into a subject with the intention of altering its biologic state with the intent of improving its health status.

Pharmacotherapy definition: Treatment of disease through the use of drugs.
Pharmaceutical Preparations definition: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.
drug/agent definition: biologically active substance, including those intended for use in diagnosis, treatment, or prevention of disease or other abnormalities, for the relief of suffering, or control or improvement of a physical or mental state; includes biological products.
Medication definition: A drug or medicine that treats or prevents or alleviates the symptoms of disease.
Medication definition: As defined in Section 201(g)(1) of the Title 21 Chapter 9 Federal Food, Drug and Cosmetic Act any article that is recognized in the official United States Pharmacopeia, official Homeopathic Pharmacopeia of the United States, or official National Formulary, or any supplement to them; article intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in humans or other animals; and article (other than food) intended to affect the structure or any function of the body of humans or other animals.
Hematologic Agents definition: Drugs that act on blood and blood-forming organs and those that affect the hemostatic system.
blood drug definition: biologically active substance intended for use in diagnosis, treatment, or prevention of blood disorders.
Drug Costs definition: The amount that a health care institution or organization pays for its drugs. It is one component of the final price that is charged to the consumer (FEES, PHARMACEUTICAL or PRESCRIPTION FEES).
Drug Approval definition: Process that is gone through in order for a drug to receive approval by a government regulatory agency. This includes any required pre-clinical or clinical testing, review, submission, and evaluation of the applications and test results, and post-marketing surveillance of the drug.
Drug Users definition: People who take drugs for a non-therapeutic or non-medical effect. The drugs may be legal or illegal, but their use often results in adverse medical, legal, or social consequences for the users.
ocular hypotensive definition: agent used to reduce elevated intraocular pressure.
Drug Interactions definition: The action of a drug that may affect the activity, metabolism, or toxicity of another drug.
drug interaction definition: physical chemical interaction between drugs and other compounds, including other drugs, particularly in biological systems.
Drug Interaction definition: Alteration of the disposition and/or effect of a drug, owing to the presence of another factor such as a second drug, or food.
Drug Discovery definition: The process of finding chemicals for potential therapeutic use.
ANTIMICROBIALS definition: NOTE: Combination products containing two or more active ingredients from the same subclassification are classified in that subclassification (e.g.,triple sulfas in AM650). Products containing two or more active ingredients from different subclassifications are classified under "anti-infectives, other" (e.g., tetracycline and amphotericin B (AM900). Products containing probenecid or clavulanic acid are classified under the subclassification of the antimicrobial agent. Beta-lactam antibiotics not classified under penicillins or cephalosporins are classified (AM130). Excludes topical anti-infectives (DE100), topical anti- infective/anti-inflammatory combinations (DE250), ophthalmic anti-infectives (OP200), ophthalmic anti- infective/anti-inflammatory combinations (OP350), otic anti-infectives (OT100), otic anti-infective/anti- inflammatory combinations (OT250); vaginal anti- infectives (GU300).
Microbicides definition: Generically, any agent that destroys microbes. However, usage of the term is increasingly being confined to agents that prevent or reduce the transmission of SEXUALLY TRANSMITTED DISEASES.
Pharmacologic Substance definition: An active natural, synthetic or semi-synthetic ingredient including endogenous body substance that is intended to furnish pharmacological activity or other direct effect in the diagnosis, cure, mitigation, treatment, or prevention of disease or to affect the structure or any function of the human body, but does not include intermediates used in the synthesis of such ingredient (21 CFR 314.3(b)).
drug addiction definition: state of heavy dependence on any drug, including alcohol; sometimes defined as physical dependence but usually also including emotional dependence, i.e., compulsive or pathological drug use.
Drug Dependence definition: Drug dependence - replaced the term "drug addiction" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug.
DA definition: Data regarding the accountability of study drug, such as information on the receipt, dispensing, return, and packaging.
Drug Accountability Domain definition: A subject domain utilized for the submission of information encompassing and representing data, vocabulary or records related to drug accountability.
Drug Agonism definition: Phenomena and pharmaceutics of compounds that selectively bind to a specific receptor and trigger a response. They mimic the action of endogenous biochemical molecules. Their effect can be countered by antagonists (DRUG ANTAGONISM).
Drug Administered definition: Identifier of Drug administered as part of procedure.
Drug Chronotherapy definition: The adaptation of drug administration to the known variations in biological RHYTHMICITY, such as CIRCADIAN RHYTHMS. The treatment is aimed at supporting normal rhythms, or modifying the timing of therapy to achieve maximal efficacy and minimal adverse effect.
medicament definition: Remède.
drug definition: Drogue, stupéfiant, narcotique.
drug definition: Remède.
narcotic definition: Drogue, stupéfiant, narcotique.
Droge definition: [1] eine Substanz biologischen Ursprungs, die eine heilende Wirkung auf den Körper hat [2] Rauschmittel [3] (übertragen) etwas von dem man abhängig ist, das einen berauscht.
Antihistaminikum definition: [1] Medizin: ein Medikament gegen Allergien, das über eine Blockade des H1- oder H2-Rezeptors antiallergisch, spasmolytisch, juckreizstillend und auch die Magensäuresekretion hemmend wirkt
Rauschgift definition: [1] Sammelbezeichnung für Stoffe, die einen Rausch verursachen
Arzneimittel definition: [1] Stoffe und Zubereitungen, die am oder im Körper angewendet werden sollen und Krankheiten heilen, Krankheitserreger abtöten oder vom Körper produzierte Wirkstoffe ersetzen können
Drogensucht definition: [1] Die Abhängigkeit von Rauschmitteln
Drogensüchtiger definition: [1] (männlicher) Mensch, der süchtig nach Drogen ist
Drogenabhängiger definition: [1] (männlicher) Mensch, der abhängig von Drogen ist
drogue definition: Substance psychotrope provoquant le plus souvent une dépendance et utilisée pour modifier son état.
drogue definition: ''(au singulier)'' Dépendance, habitude, période pendant laquelle on prend des psychotropes.
drogue definition: Chose qui intoxique, qui provoque comme une dépendance, passe-temps ou hobby très prenant.
drogue definition: Nom générique de divers ingrédients qui s’emploient surtout en pharmacie ou pour la teinture.
drogue definition: Chose qui n’a pas de valeur.
médicament definition: Substance ou composition possédant des propriétés curatives ou préventives, destiner|destinées à guérir, à soulager ou à prévenir des maladies humaines ou animales.
remède definition: Substance qui sert à guérir un mal ou une maladie.
remède definition: Ce qui sert à guérir les maladies de l’âme.
remède definition: Ce qui sert à prévenir, surmonter ou faire cesser un malheur, un inconvénient ou une disgrâce.
remède definition: Lavement.
stupéfiant definition: Qui stupéfie.
toxicomanie definition: Consommation répétée et excessive d'une ou plusieurs substances toxiques (analgésiques, psychotropes, excitants, etc.) sans justification thérapeutique. Cet usage s'accompagne d'une addiction incontrôlable, accompagnée d'accoutumance et de dépendance.
antiviral definition: Molécule perturbant le cycle de réplication d'un ou de plusieurs virus, permettant ainsi de ralentir et plus rarement de stopper une infection virale.
drug definition: Drogue, stupéfiant.
narcoticum definition: Drogue, stupéfiant.