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Adrenergic Agents definition: Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters.
adrenergic agent definition: drugs that selectively bind to and activate adrenergic receptors or mimic the actions of adrenergic transmitters; for adrenergic antagonists, see ANTIADRENERGIC AGENT.
Adrenergic Agent definition: Refer to a class of agents that acts upon adrenergic receptors associated with activities of Sympathetic Nerve System. The adrenergic receptors (adrenoceptors) belongs to the family of seven membrane spanning domain receptors that require G protein signaling pathway. (NCI04)
Adrenergic Agonists definition: Drugs that bind to and activate adrenergic receptors.
Analgesics definition: Compounds capable of relieving pain without the loss of CONSCIOUSNESS.
analgesic definition: compounds capable of relieving pain without the loss of consciousness or without producing anesthesia.
analgesics definition: Drugs that reduce pain. These drugs include aspirin, acetaminophen, and ibuprofen.
Analgesic Preparation definition: Natural or synthetic compound mixtures, Analgesic Preparations relieve pain by altering the perception of nociceptive stimuli without loss of consciousness. Analgesic compounds may act at opioid receptors (morphine-like drugs) or at other central or peripheral sites (non-steroidal anti-inflammatory agents). (NCI04)
Analgesic Agent definition: Compounds that alleviate pain without loss of consciousness. Analgesics act by various mechanisms including binding with opioid receptors and decreasing inflammation. Choice of analgesic may be determined by the type of pain. These compounds include opioid, non-opioid and adjuvant analgesic agents.
Anesthetics definition: Agents that are capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general ANESTHESIA, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.
anesthetic definition: agents that are capable of inducing a total or partial loss of sensation, especially tactile sensation and pain; may act to induce general anesthesia, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site.
anesthetics definition: (an-es-THET-iks) Substances that cause loss of feeling or awareness. Local anesthetics cause loss of feeling in a part of the body. General anesthetics put the person to sleep.
Anesthetic Agent definition: Agents that are capable of inducing a total or partial loss of sensation, especially tactile sensation and pain. They may act to induce general anesthesia, in which an unconscious state is achieved, or may act locally to induce numbness or lack of sensation at a targeted site. (MeSH)
Anthelmintics definition: Agents destructive to parasitic worms. They are used therapeutically in the treatment of HELMINTHIASIS in man and animal.
anthelmintic definition: substance that destroys helminth parasitic worms or prevents their growth or replication; used therapeutically in the treatment of helminthiasis.
Antihelminthic Agent definition: Agents destructive to parasitic worms. They are used therapeutically in the treatment of helminthiasis in man and animal. (MeSH)
antirheumatic agent definition: agent that relieves or prevents rheumatic disease, especially rheumatoid arthritis.
Antirheumatic Agents definition: Drugs that are used to treat RHEUMATOID ARTHRITIS.
Anti-Arrhythmia Agents definition: Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade.
antiarrhythmic agent definition: group of agents used for the treatment or prevention of cardiac arrhythmias; they may effect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
Antiarrhythmic Agent definition: Agents used for the treatment or prevention of cardiac arrhythmias; they may effect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers.
arrhythmic agent definition: agent causing or promoting cardiac arrhythmias.
Anti-Infective Agents definition: Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
antiinfective agent definition: substances that kill or prevent the spreading of infectious agents or organisms in order to prevent the spread of infection.
Anti-Infective Agent definition: Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (MeSH)
Anti-infective Preparation definition: For internal or topical application, Anti-infective Preparations contain natural or synthetic antibiotic agents that act therapeutically or prophylactically against infectious viral, bacterial, protozoal, or other agents by inhibiting their growth, replication, and survival. Usually, antiinfective preparations are formulated sterile. (NCI04)
antibiotic definition: substances produced by microorganisms or biomimetics that can inhibit or suppress the growth of other microorganisms; frequently used without reference to the microbial origins of the original substance.
antibiotic definition: (an-tih-by-AH-tik) A drug used to treat infections caused by bacteria and other microorganisms.
Antibiotic definition: Substances naturally produced by microorganisms or their derivatives that selectively target microorganisms not humans. Antibiotics kill or inhibit the growth of microorganisms by targeting components of the microbial cell absent from human cells, including bacterial cell walls, cell membrane, and 30S or 50S ribosomal subunits. These substances are used in the treatment of bacterial and other microbial infections.
Antibiotics definition: Substances produced by microorganisms that can inhibit or suppress the growth of other microorganisms.
aminoglycoside antibiotic definition: any of a group of antibiotics derived from various species of Streptomyces or produced synthetically; they inhibit protein synthesis by binding with the 30S ribosomal subunit.
aminoglycoside antibiotics definition: A family of antibiotics that works against many types of bacteria and includes streptomycin, gentamicin, and neomycin. Aminoglycosides are used to treat bacterial infections.
Aminoglycoside Antibiotic definition: A broad spectrum antibiotic family derived from Streptomyces containing aminoglycosides that bind to bacterial ribosomes, inhibiting protein synthesis.
Anticholesteremic Agents definition: Substances used to lower plasma cholesterol levels.
antihypercholesterolemic agent definition: agents which reduce or control high cholesterol and bring about lower cholesterol levels in both the blood and the liver.
Anticoagulants definition: Agents that prevent blood clotting. Naturally occurring agents in the blood are included only when they are used as drugs.
anticoagulant definition: externally administered agents that prevent blood clotting.
blood thinner definition: A drug that helps prevent blood clots from forming. Also called a blood thinner.
Anticonvulsants definition: Drugs used to prevent SEIZURES or reduce their severity.
anticonvulsant definition: agent used to prevent seizures or reduce their severity.
anticonvulsants definition: (an-tee-kon-VUL-sants) Drugs that prevent, reduce, or stop convulsions or seizures.
Anticonvulsant Agent definition: Medicine to stop, prevent, or control seizures (convulsions).
Antidepressive Agents definition: Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
antidepressant definition: mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
antidepressant definition: A drug used to treat depression.
Antidepressant Agent definition: Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several monoamine oxidase inhibitors are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents also appear to act through brain catecholamine systems. A third group is a diverse group of drugs including some that act specifically on serotonergic systems. (MeSH)
Antidiarrheals definition: Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition.
Antidiarrheal Agent definition: Miscellaneous agents found useful in the symptomatic treatment of diarrhea. They have no effect on the agent(s) that cause diarrhea, but merely alleviate the condition. (MeSH)
Antiemetics definition: Drugs used to prevent NAUSEA or VOMITING. Antiemetics act by a wide range of mechanisms. Some act on the medullary control centers (the vomiting center and the chemoreceptive trigger zone) while others affect the peripheral receptors.
antiemetic definition: drugs used to prevent nausea or vomiting; act by a wide range of mechanisms; some act on the medullary control centers while others effect the peripheral receptors.
antiemetics definition: Drugs that prevent or reduce nausea and vomiting.
Antiemetic Agent definition: Drugs used to prevent nausea or vomiting. Antiemetics act by a wide range of mechanisms. Some act on the medullary control centers (the vomiting center and the chemoreceptive trigger zone) while others affect the peripheral receptors. (MeSH)
Antihypertensive Agents definition: Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
antihypertensive agent definition: agent that reduces high blood pressure.
Antihypertensive Agent definition: Any substance used in the treatment of acute or chronic hypertension regardless of pharmacological mechanism. Antihypertensive agents include diuretics, alpha-adrenergic and beta-adrenergic antagonists, angiotensin-converting enzyme inhibitors, calcium channel blockers, ganglionic blockers, and vasodilator agents.
Antilipemic Agents definition: Substances used to treat HYPERLIPIDEMIAS.
antihyperlipoproteinemic agent definition: agent that promotes a reduction of lipoprotein levels in the blood.
Antimalarials definition: Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)
antimalarial agent definition: agent used in the treatment or prevention of malaria.
Antimalarial Agent definition: Agents used to treat malaria, and are usually classified based on action against plasmodia at different stages in their life cycle in the human.
antimitotic definition: agent that inhibits or prevents mitosis.
mitotic inhibitors definition: Drugs that kill cancer cells by interfering with cell division (mitosis).
Antimitotic Agents definition: Agents that arrest cells in MITOSIS, most notably TUBULIN MODULATORS.
Antinematodal Agents definition: Substances used in the treatment or control of nematode infestations. They are used also in veterinary practice.
Antineoplastic Agents definition: Substances that inhibit or prevent the proliferation of NEOPLASMS.
antineoplastic definition: agent that inhibits or prevents the development or proliferation of neoplasms.
chemotherapeutic agent definition: A drug used to treat cancer.
chemotherapeutic agent definition: A substance that blocks the formation of neoplasms (growths that may become cancerous).
ANTINEOPLASTICS definition: NOTE: Includes hormones (AN500) which are exclusively used as antineoplastics (e.g.,tamoxifen). Excludes other hormones (HS000).
Antineoplastic Agent definition: A substance that inhibits the maturation, growth or spread of tumor cells.
Antiparasitic Agents definition: Drugs used to treat or prevent parasitic infections.
antiparasitics definition: Drugs used to treat bacterial and parasitic infections and some cancers.
ANTIPARASITICS definition: NOTE: Includes topical pediculicides (AP300).
antiparasitic agent definition: drug or agent used to treat or prevent parasitic infections.
Antiparkinson Agents definition: Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.
antiparkinson drug definition: agent used in the treatment of Parkinson's disease; the most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists.
Antiplatyhelmintic Agents definition: Agents used to treat cestode, trematode, or other flatworm infestations in man or animals.
Antiprotozoal Agents definition: Substances that are destructive to protozoans.
antiprotozoal agent definition: substance that destroys protozoans, or that prevents their growth or reproduction.
Antiprotozoal Agent definition: Substances that are destructive to protozoans. (MeSH)
Antipruritics definition: Agents, usually topical, that relieve itching (pruritus).
Antitreponemal Agents definition: Agents used to treat infections with bacteria of the genus TREPONEMA. This includes SYPHILIS & YAWS.
Antitrichomonal Agents definition: Agents used to treat trichomonas infections.
Antitubercular Agents definition: Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.
antitubercular agent definition: drug used in the treatment of tuberculosis.
antituberculosis definition: Having to do with a drug used to treat tuberculosis.
Antitussive Agents definition: Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
Antitussive Agent definition: Any substance that is capable of relieving or suppressing coughing.
Antiviral Agents definition: Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
antiviral agent definition: drug that destroys viruses or prevents their growth or replication.
antivirals definition: Drugs used to treat infections caused by viruses.
Miscellaneous Antiviral Agent definition: Antiviral agents that have a non-specific classification.
Appetite Depressants definition: Agents that are used to decrease appetite.
anorexic agent definition: class of drugs which suppress appetite, used for weight control.
Anorexiant definition: Any substance that induces loss of appetite to prevent weight gain and achieve weight loss.
Autonomic Agents definition: Agents affecting the function of, or mimicking the actions of, the autonomic nervous system and thereby having an effect on such processes as respiration, circulation, digestion, body temperature regulation, certain endocrine gland secretions, etc.
autonomic agent definition: agent effecting the function of, or mimicking the actions of, the autonomic nervous system and thereby having an effect on such processes as respiration, circulation, digestion, body temperature regulation, certain endocrine gland secretions, etc.
Cardiotonic Agents definition: Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).
cardiotonic agent definition: agents that have a strengthening effect on the heart or that can increase cardiac output.
Cardioprotective Agent definition: An agent that prevents damage to the heart, thereby protecting myocardial function.
Cardiovascular Agents definition: Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
cardiovascular agent definition: agents that effect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.
Central Nervous System Agents definition: A class of drugs producing both physiological and psychological effects through a variety of mechanisms. They can be divided into "specific" agents, e.g., affecting an identifiable molecular mechanism unique to target cells bearing receptors for that agent, and "nonspecific" agents, those producing effects on different target cells and acting by diverse molecular mechanisms. Those with nonspecific mechanisms are generally further classed according to whether they produce behavioral depression or stimulation. Those with specific mechanisms are classed by locus of action or specific therapeutic use. (From Gilman AG, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p252)
centrally acting drug definition: class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system.
Cholinesterase Inhibitors definition: Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
cholinesterase inhibitor definition: any substance or agent which suppresses, prevents or opposes the action of cholinesterase resulting in the potentiation of the action of endogenously released acetylcholine at cholinergic synapses; cholinesterase inhibition is associated with a variety of acute symptoms such as nausea, vomiting, blurred vision, stomach cramps, and rapid heart rate.
Contraceptive Agents definition: Chemical substances that prevent or reduce the probability of CONCEPTION.
contraceptive definition: agent that diminishes the likelihood of or prevents conception; may be chemical, physical, or behavioral.
Contrast Media definition: Substances used to allow enhanced visualization of tissues.
contrast media definition: substances used in radiography that allow visualization of certain tissues.
Contrast Agent definition: Substances administered during diagnostic procedures that allows delineation of internal structures. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue.
Neuromuscular Nondepolarizing Agents definition: Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants.
Cytostatic Agents definition: Compounds that inhibit or prevent the proliferation of CELLS.
Designer Drugs definition: Drugs designed and synthesized, often for illegal street use, by modification of existing drug structures (e.g., amphetamines). Of special interest are MPTP (a reverse ester of meperidine), MDA (3,4-methylenedioxyamphetamine), and MDMA (3,4-methylenedioxymethamphetamine). Many drugs act on the aminergic system, the physiologically active biogenic amines.
Dopamine Agents definition: Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
Drug Abuse definition: Excessive use of habit forming medications.
drug abuse definition: excessive use of drugs or chemicals with associated psychological symptoms and impairment in social or occupational functioning.
Drug Abuse definition: The use of a drug for a reason other than which it was intended or in a manner or in quantities other than directed.
Pharmaceutical Preparations definition: Drugs intended for human or veterinary use, presented in their finished dosage form. Included here are materials used in the preparation and/or formulation of the finished dosage form.
drug/agent definition: biologically active substance, including those intended for use in diagnosis, treatment, or prevention of disease or other abnormalities, for the relief of suffering, or control or improvement of a physical or mental state; includes biological products.
Medication definition: A drug or medicine that treats or prevents or alleviates the symptoms of disease.
Medication definition: As defined in Section 201(g)(1) of the Title 21 Chapter 9 Federal Food, Drug and Cosmetic Act any article that is recognized in the official United States Pharmacopeia, official Homeopathic Pharmacopeia of the United States, or official National Formulary, or any supplement to them; article intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in humans or other animals; and article (other than food) intended to affect the structure or any function of the body of humans or other animals.
antispasmodic agent definition: agent that relieves spasm, usually of smooth muscles as in arteries, bronchi, intestine, bile duct, or ureters, but also of voluntary muscle.
Antispasmotic Agent definition: Natural or synthetic Antispasmodic Agents (commonly anticholinergic) relieve spasms or cramps of the stomach, intestines, and bladder. These agents often decrease secretions (acid and enzymes) and movements of the stomach and intestine. (NCI04)
thyroid inhibitor definition: any agent or substance which suppresses, prevents or opposes the biosynthesis of thyroid hormones.
Antithyroid Agents definition: Agents that are used to treat hyperthyroidism by reducing the excessive production of thyroid hormones.
Antipsychotic Agents definition: Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in schizophrenia, senile dementia, transient psychosis following surgery or myocardial infarction, etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
antipsychotic agent definition: class of drugs used to treat symptoms of schizophrenia and other psychotic behavior; includes neuroleptics.
Antipsychotic Agent definition: Also known as neuroleptics, major tranquilizers, or antischizophrenics, natural or synthetic. Antipsychotic Agents relieve and control the symptoms of schizophrenic illness (hallucinations, delusions, dementia). Most antipsychotic agents interfere with various neurotransmitter functions, often blocking dopamine receptors, and induce diverse behavioral, endocrine, motor-kinetic effects. (NCI04)
Anticarcinogenic Agents definition: Agents that reduce the frequency or rate of spontaneous or induced tumors independently of the mechanism involved. They differ from antineoplastic agents in that they prevent neoplasms from forming. The anticarcinogenic substances can be divided into three categories. The first consists of compounds that prevent the formation of carcinogens from precursor substances. The second group consists of "blocking agents" which inhibit carcinogenesis by preventing carcinogenic agents from reaching or reacting with critical target sites in the tissues. The third group is the "suppressor agents" which act by suppression of expression of neoplasia in cells previously exposed to carcinogens that would otherwise cause neoplasms.
Antiplatelet Agent definition: An agent that inhibits platelet aggregation and reduces coagulation in the circulatory system.
antiadrenergic agent definition: group of drugs that bind to but do not activate adrenergic receptors; they block the actions of the endogenous adrenergic transmitters epinepherine and norepinepherine.
Adrenergic Antagonists definition: Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters EPINEPHRINE and NOREPINEPHRINE.
Cholinergic Agents definition: Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage.
cholinergic agent definition: drug used for its actions in stimulating cholinergic systems.
Antimanic Agents definition: Agents that are used to treat bipolar disorders or mania associated with other affective disorders.
Adrenal Agent definition: Pharmacological agents which affect the function of the adrenal glands.
Anti-Allergic Agents definition: Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475)
antiallergic agent definition: group of agents that are used to treat allergic reactions; most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells.
Anti-Asthmatic Agents definition: Drugs that are used to treat asthma.
Anti-asthmatic Agent definition: Classified as bronchodilators (beta-adrenoreceptor agonists, xanthines, muscarinic-receptor antagonists) and anti-inflammatory agents (glucocorticoids, cromolyn), natural or synthetic Anti-asthmatic Agents relieve asthma (a recurrent airway obstruction) in multiple ways and at various sites, by reducing bronchial spasm, dyspnea, allergic reaction, local inflammation, and pain. Other agents, such as anti-histamine and antibiotics, may also be used in asthma. (NCI04)
Anti-HIV Agents definition: Agents used to treat AIDS and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with AIDS.
antiAIDS agent definition: agents used to treat AIDS and/or stop the spread of the HIV infection; frequently used in a combination cocktail or mixture of therapeutics; for specific agents, SEE also ANTIVIRAL AGENT.
Anti-Obesity Agents definition: Agents that increase energy expenditure and weight loss by neural and chemical regulation. Beta-adrenergic agents and serotoninergic drugs have been experimentally used in patients with non-insulin dependent diabetes mellitus (NIDDM) to treat obesity.
angiogenesis inhibitor definition: A substance that may prevent the formation of blood vessels. In anticancer therapy, an angiogenesis inhibitor prevents the growth of blood vessels from surrounding tissue to a solid tumor.
angiogenesis inhibitor definition: agents or endogenous substances that suppress, prevent, or oppose the development of new blood vessels.
Angiogenesis Inhibitors definition: Agents and endogenous substances that antagonize or inhibit the development of new blood vessels.
Angiogenesis Inhibitor definition: An agent or endogenous substance that inhibits the formation and growth of blood or lymphatic vessels. In cancer therapy, angiogenesis inhibitors target blood vessels that supply tumors, thereby inhibiting tumor growth. (NCI04)
Anti-diabetic Agent definition: Any substance used to reduce hyperglycemia or treat disorders associated with diabetes. Based on their mechanism of action, this class of agents can be classified to the following groups: directly acting insulomimetics, which activates insulin receptors; indirectly acting insulinomimetics, which increase insulin release such as sulfonylureas or which potentiate the effect of insulin such as metformin; those act directly on the metabolism of glucose such as inhibitors of glucosidases and inhibitors of aldose reductase.
Cytoprotective Agent definition: Agents administered before, with, or after cancer therapy to reduce or prevent damage or toxicity to the normal cells. (NCI)
chemoprotective definition: A quality of some drugs used in cancer treatment. Chemoprotective agents protect healthy tissue from the toxic effects of anticancer drugs.
Chemoprotective Agent definition: Chemicals which protect normal cells from the effects of chemotherapy.
Miscellaneous Chemoprotective Agent definition: Chemoprotective agents with non-specific classification based on mechanism of action, therapeutic use, or chemical properties. (NCI)
anticachexia definition: Refers to a drug used to treat cachexia.
Anticachexia Agent definition: Drugs which reduce the fatigue and weight loss often associated with cancer.
Pharmaceutical Preparations, Dental definition: Drugs intended for DENTISTRY.