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Definition
 
enEnglish
Immunosuppression definition: Deliberate prevention or diminution of the host's immune response. It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs.
artificial immunosuppression definition: deliberate suppression of immune system function for experimental or therapeutic purposes.
immunosuppressive therapy definition: Therapy used to decrease the body's immune response, such as drugs given to prevent transplant rejection.
immunosuppressive therapy definition: Suppression of the body's immune system and its ability to fight infections or disease. Immunosuppression may be deliberately induced with drugs, as in preparation for bone marrow or other organ transplantation to prevent rejection of the donor tissue. It may also result from certain diseases such as AIDS or lymphoma or from anticancer drugs.
Ovulation Inhibition definition: Blocking the process leading to OVULATION. Various factors are known to inhibit ovulation, such as neuroendocrine, psychological, and pharmacological agents.
Suppression, Genetic definition: Mutation process that restores the wild-type PHENOTYPE in an organism possessing a mutationally altered GENOTYPE. The second "suppressor" mutation may be on a different gene, on the same gene but located at a distance from the site of the primary mutation, or in extrachromosomal genes (EXTRACHROMOSOMAL INHERITANCE).
Bone Marrow Suppression definition: A condition in which the production of red blood cells, white blood cells, and/or platelets by bone marrow stem cells is inhibited, usually as a side effect of treatment with various anti-cancer agents, radiation, or tumor development within the bone marrow.
dexamethasone suppression test definition: injection of dexamethasone causes serum cortisol to fall; this can be correlated with behavioral measures of depression, but the test is not reliable enough for diagnostic use.
ovarian suppression definition: Surgery, radiation therapy, or a drug treatment to stop the functioning of the ovaries.
suppression definition: conscious inhibition of an unacceptable impulse or idea.
ST5 Gene definition: This gene plays a role in signal transduction and tumor suppression.
NBL1 Gene definition: This gene plays a regulatory role in cellular growth and maintenance.
suppression by virus of host apoptosis definition: Any viral process that results in the inhibition of apoptosis, facilitating prolonged cell survival during viral replication. [ISBN:0781718325]
negative regulation of cardioblast cell fate specification definition: Any process that restricts, stops or prevents a cell from specifying into a cardioblast. [GOC:go_curators]
negative regulation of ectodermal cell fate specification definition: Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell. [GOC:go_curators]
negative regulation of cell fate specification definition: Any process that restricts, stops or prevents a cell from adopting a specific cell fate. [GOC:go_curators]
Adhesion Factor Suppression definition: By decreased production or increased degradation, Adhesion Factor Suppression consists of interference with, or restraint of, the expression or activity of cell surface proteins involved in cell-cell or cell-matrix attachment. Such suppression alters maintenance of tissue integration, wound healing, cellular migrations, and metastasis.
Cytokine Suppression definition: Through increased degradation, or decreased production or receptor binding, Cytokine Suppression involves interference with, or restraint of, the activity of a class of soluble non-antibody paracrine or autocrine signaling glycoproteins (cytokines) secreted by immune cells that regulate immune responses through high affinity binding with specific receptors. Cytokines act as intercellular mediators regulating immune and inflammatory responses. Suppression decreases cell proliferation and differentiation, secretion of other biologically active molecules, and responses to immune and inflammatory stimuli.
Immune Cell Suppression definition: Immune Cell Suppression consists of interference with, or restraint of, the activity of one or more lymphoid or myeloid cell types associated with the immune response.
Immunologic Factor Suppression definition: By increased degradation, or decreased production or receptor binding, Immunologic Factor Suppression involves interference with, or restraint of, the activities of antibody or cytokine proteins that affect immune functions, immune responses, or inflammation.
Interferon Suppression definition: Through increased degradation, or decreased production or receptor binding, Interferon Suppression involves interference with, or restraint of, the activities of secreted proteins (alpha, beta, and gamma interferon types) that confer viral resistance, inhibit cell proliferation, enhance phagocytosis, augment NK cell activity, and show other immunomodulatory functions.
Interleukin Suppression definition: Through increased degradation, or decreased production or receptor binding, Interleukin Suppression involves interference with, or restraint of, the activities of soluble cytokine factors with broad regulatory function (interleukins) produced by leukocytes and other cells that enhance leukocyte cell proliferation and differentiation, promote secretion of biologically active molecules, and regulate immune and inflammatory responses.
Metastasis Suppression definition: Metastasis Suppression involves interference or restraint of the spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor (NCI)
Myeloid Cell Suppression definition: Myeloid Cell Suppression involves interference with, or restraint of, the production and activity of myeloid cells. Formed in the bone marrow, myeloid cells are leukocytes that defend the body against foreign substances. These cells include monocytes and granulocytes that protect the body against invading substances by ingesting or phagocytizing them. Suppression decreases the body's ability to combat disease and toxic substances.
Platelet Activating Factor Suppression definition: By increased degradation, or decreased production or receptor binding, Platelet Activating Factor Suppression involves interference with, or restraint of, the activity of a phospholipid derivative (platelet activating factor) formed by platelets, basophils, neutrophils, monocytes, and macrophages that acts as a potent agent of platelet aggregation, inflammation, neutrophil activity, prostaglandin synthesis, and systemic anaphylaxis: hypotension, thrombocytopenia, neutropenia, and bronchoconstriction.
Suppression of Cancer Cell Invasion definition: Suppression of Cancer Cell Invasion involves the inhibition of infiltration and destruction of surrounding tissue by malignant cells.
androgen suppression definition: Treatment to suppress or block the production of male hormones. Androgen suppression is achieved by surgical removal of the testicles, by taking female sex hormones, or by taking other drugs, antiandrogens. Also called androgen ablation.
Androgen Suppression definition: Blockage of the production of male hormones.
Antibody Suppression definition: Antibody Suppression involves interference with, or restraint of, the activity of a class of cell-surface or secreted B lymphocyte proteins that non-covalently interact through intermolecular physical forces of attraction and spatial complementarity selectively and specifically with foreign substances (antigens), typically as part of an immune response. Suppression mechanisms include increased degradation or decreased production and binding to antigen.
Cellular Tumor Suppression definition: Cellular Tumor Suppression is thought to involve elimination of cells that have undergone malignant transformation by patrolling cytotoxic T cells, NK cells, and macrophages due to recognition of altered cell surface antigens on the cancer cells.
Colony Stimulating Factor Suppression definition: Through increased degradation, or decreased production or receptor binding, Colony Stimulating Factor Suppression involves interference with, or restraint of, the activities of synergistic paracrine or autocrine glycoprotein growth factors (IL-3, G-CSF, M-CSF, and GM-CSF) that stimulate myeloid cell proliferation and differentiation of granulocyte and/or macrophage colonies.
Complement Suppression definition: By increased degradation, or by decreased production or activation, Complement Suppression consists of interference with, or restraint of, the activities of sequentially interacting serum proteins (some serine proteases), their receptors, and related regulatory proteins activated by cell-surface bound antibody, immune complexes, or a microbial membrane carbohydrate and involved in complex cascades (classical or properdin pathway) that generate Membrane Attack Complex, which creates target cell wall pores and lysis. The complement system also plays a role in antibody-dependent cytolysis, anaphylaxis, phagocytosis, opsonization, chemotaxis, and hemolysis.
Free Radical Suppression definition: Free Radical Suppression involves interference with, or restraint of, production in normal or pathological processes of chemically unstable, short half-life and highly reactive molecules carrying at least one unpaired or 'free' electron in the outermost electron shell. Appropriating electron(s) from a nearby molecule and damaging that molecule by altering the electron number in its outermost electron shell, Free Radicals produce tissue damage.
Lymphocyte Suppression definition: Lymphocyte Suppression involves interference with, or restraint of, the production and activity of lymphocytes. Formed in lymphoid tissue, lymphocytes are white blood cells that can generally be classified as either T- or B-cells. T-lymphocytes provide cell-mediated immunity, while B-lymphocytes produce antibodies that provide humoral immunity. Suppression decreases the ability of lymphocytes to mount an immune response to invading substances.
Tumor Suppression definition: Tumor Suppression involves inhibition of tumor cell growth, proliferation, malignancy, or metastasis.
negative regulation of appetite definition: Any process that reduces appetite. [GOC:add]
Cosuppression definition: Joint gene silencing of extra copies of genes, such as TRANSGENES, along with the original endogenous gene. Cosuppression is induced by the presence of the extra gene copies via mechanisms that are related to RNA INTERFERENCE.
suppression definition: Suppression.
 
 
deGerman
kupieren definition: [1] durch Schneiden kürzen (Pflanzen/Tiere) [2] einen Kranheitsprozess aufhalten oder unterdrücken(Medizin)
Kupierung definition: [1] durch Schneiden kürzen (Pflanzen/Tiere) [2] einen Kranheitsprozess aufhalten oder unterdrücken(Medizin)
Vernichtung definition: [1] Vorgang oder Ergebnis eines Prozesses, der etwas ganz und gar zerstört, so dass der ursprüngliche Zustand (Gegenstand) kaum noch oder gar nicht mehr erkennbar ist.
 
itItalian
condensatore antidisturbo definition: [1] (Elektronik) der Entstörkondensator, der Entstörungskondensator
 
frFrench
ellipse definition: ## Courbe, en forme de cercle allongé, dont chacun des points est tel que la somme des distances à deux points fixes, dits foyers, est constante.
ellipse definition: ## Suppression d’un élément de phrase sans changement de signification.
suppression definition: Action de supprimer.
suppression definition: Suspension d’une évacuation accoutumée.
suppression definition: