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Acromegaly definition: WHAT: Acromegaly: Hypersecretion of growth hormone from a pituitary tumor resulting in insidious increase in the skeleton, soft tissues and organs. WHY: Acromegaly can result in an arthropathy with initial cartilage hypertrophy resulting in widening of the cartilage space on radiographs. The cartilage then undergoes premature osteoarthritis change with productive bony change characterized by broad distal tufts in the phalanges.
Acromegaly definition: A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80)
acromegaly definition: disorder caused by excessive secretion of somatotropin, characterized by bony enlargement of face, hands, feet, head and thorax.
Growth Hormone Producing Pituitary Gland Adenoma definition: An adenoma of the anterior lobe of the pituitary gland that produces growth hormone. The vast majority of cases are hormonally functioning and are associated with either gigantism or acromegaly. (NCI05)
Growth Hormone-Secreting Pituitary Adenoma definition: A pituitary tumor that secretes GROWTH HORMONE. In humans, excess HUMAN GROWTH HORMONE leads to ACROMEGALY.
acromegaly definition: Acromégalie.