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alpha antiadrenergic agent definition: drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists; adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Adrenergic alpha-Antagonists definition: Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Alpha-Adrenergic Antagonist definition: Natural or synthetic Alpha-adrenergic Blocking Agents selectively bind to adrenergic receptors, or compete with natural adrenergic mediators, and inactivate alpha adrenergic receptors of the sympathetic nervous system. These agents block the action of natural sympathomimetic neurotransmitters (norepinephrine and related substances), and can initiate physiological responses such as vasodilation, bradycardia, and pupil contraction. (NCI04)
Adrenergic beta-Antagonists definition: Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Beta-Adrenergic Antagonist definition: Natural or synthetic Beta Adrenergic Blocking Agents typically bind to - but do not activate - beta-adrenergic receptors, blocking or diminishing physiologic beta-adrenergic agonist actions and activation of the sympathetic system. Reducing cardiac output, beta adrenergic antagonists are generally used for treatment of hypertension, cardiac arrythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. (NCI04)
Anesthetics, Local definition: Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
local anesthetic definition: drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations; they act on any part of the nervous system and on every type of nerve fiber; their action is completely reversible.
Calcium Channel Blockers definition: A class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. Since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms.
calcium channel blocker definition: class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools; since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in the relaxation of uterine spasms.
Neuromuscular Nondepolarizing Agents definition: Drugs that interrupt transmission at the skeletal neuromuscular junction without causing depolarization of the motor end plate. They prevent acetylcholine from triggering muscle contraction and are used as muscle relaxants during electroshock treatments, in convulsive states, and as anesthesia adjuvants.
ganglionic blocking agent definition: group of agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons; because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs.
Ganglionic Blockers definition: Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Histamine H2 Antagonists definition: Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Neuromuscular Blocking Agents definition: Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc.
neuromuscular blocking agent definition: drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction; they prevent acetylcholine from triggering muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, and in convulsive states.
Neuromuscular Depolarizing Agents definition: Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation.
depolarizing neuromuscular blocking agent definition: drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate; primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation.
Parasympatholytics definition: Agents that inhibit the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the MUSCARINIC ANTAGONISTS.
Spermatogenesis-Blocking Agents definition: Chemical substances which inhibit the process of spermatozoa formation at either the first stage, in which spermatogonia develop into spermatocytes and then into spermatids, or the second stage, in which spermatids transform into spermatozoa.
Sympatholytics definition: Drugs that inhibit the actions of the sympathetic nervous system by any mechanism. The most common of these are the ADRENERGIC ANTAGONISTS and drugs that deplete norepinephrine or reduce the release of transmitters from adrenergic postganglionic terminals (see ADRENERGIC AGENTS). Drugs that act in the central nervous system to reduce sympathetic activity (e.g., centrally acting alpha-2 adrenergic agonists, see ADRENERGIC ALPHA-AGONISTS) are included here.
antiadrenergic agent definition: group of drugs that bind to but do not activate adrenergic receptors; they block the actions of the endogenous adrenergic transmitters epinepherine and norepinepherine.
Adrenergic Antagonists definition: Drugs that bind to but do not activate ADRENERGIC RECEPTORS. Adrenergic antagonists block the actions of the endogenous adrenergic transmitters EPINEPHRINE and NOREPINEPHRINE.
Cholinergic Antagonists definition: Drugs that bind to but do not activate CHOLINERGIC RECEPTORS, thereby blocking the actions of ACETYLCHOLINE or cholinergic agonists.
Antibodies, Blocking definition: Antibodies that inhibit the reaction between ANTIGEN and other antibodies or sensitized T-LYMPHOCYTES (e.g., antibodies of the IMMUNOGLOBULIN G class that compete with IGE antibodies for antigen, thereby blocking an allergic response). Blocking antibodies that bind tumors and prevent destruction of tumor cells by CYTOTOXIC T-LYMPHOCYTES have also been called enhancing antibodies. (Rosen et al., Dictionary of Immunology, 1989)
blocking antibody definition: antibody which interferes with the reactivity of the others by binding available epitopes of homologous specificity; or, univalent antibody that can coat antigen bearing cells but not agglutinate them.
Blocking Antibody definition: An antibody that prevents some reaction from taking place, for example one antibody competing with another for a cell surface receptor.
Block definition: Interrupt the normal function of; hinder or prevent the progress or accomplishment of; stop from happening or developing; interfere with or prevent the reception of signals; impede the movement of.
Cabinets, Storage, Radiotherapy Blocking Tray definition: Cabinets designed to provide space to storage the plastic (e.g., polycarbonate, acrylic) trays used in radiation therapy treatments (i.e., blocking trays). These cabinets typically consist of a set of compartments for placing each blocking tray in a separate bin. The cabinets are typically made of metal, wood, particle board, or a combination of these. Most cabinets are intended for wall mounting. They are available in several sizes depending on hospital needs. Blocking-tray cabinets are used in radiology and nuclear medicine departments.
replication fork arrest definition: Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. [GOC:jl, PMID:14645529]
 
 
deGerman
Sperrminorität definition: [1] Politik: die Möglichkeit einer Minderheit, bei Abstimmungen einen bestimmten Beschluss zu verhindern. Sperrminoritäten entstehen dort, wo qualifizierte Mehrheiten verlangt werden. [2] Wirtschaft: Minderheitsbeteiligung an einem Unternehmen, mit der wichtige Beschlüsse des Unternehmens verhindert werden können