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Alkylmercury Compounds definition: Organic mercury compounds in which the mercury is attached to an alkyl group.
Alkynes definition: Hydrocarbons with at least one triple bond in the linear portion, of the general formula Cn-H2n-2.
alkyne definition: unsaturated hydrocarbon containing a triple bond between two carbon atoms; the alkynes are members of the acetylene series.
allyl compound definition: substance that consists of two or more chemical elements in union and containing the univalent organic group, -CH2 or allyl.
Alum Compounds definition: Aluminum metal sulfate compounds used medically as astringents and for many industrial purposes. They are used in veterinary medicine for the treatment of ulcerative stomatitis, leukorrhea, conjunctivitis, pharyngitis, metritis, and minor wounds.
Aminobiphenyl Compounds definition: Biphenyl compounds substituted in any position by one or more amino groups. Permitted are any substituents except fused rings.
biphenylamine definition: nitrogen substituted aromatic amine formerly used in dyemaking; now used to induce cancer in laboratory animals.
ammonium compound definition: inorganic and organic compounds that contain the radical NH4 or ammonium.
Ammonium Compounds definition: Inorganic and organic compounds that contain the hypothetical radical NH4.
Androgens definition: Compounds that interact with ANDROGEN RECEPTORS in target tissues to bring about the effects similar to those of TESTOSTERONE. Depending on the target tissues, androgenic effects can be on SEX DIFFERENTIATION; male reproductive organs, SPERMATOGENESIS; secondary male SEX CHARACTERISTICS; LIBIDO; development of muscle mass, strength, and power.
androgen definition: compounds that interact with androgen receptors in target tissues to bring about the effects similar to those of testosterone; depending on the target tissues, androgenic effects can be on sexual differentiation, male reproductive organs, spermtogenesis, secondary male sex characteristics, libido, development of muscle mass, strength, and power.
androgen definition: (AN-dro-jens) A family of hormones that promote the development and maintenance of male sex characteristics.
Therapeutic Androgen definition: A class of sex hormones associated with the development and maintenance of the secondary male sex characteristics, sperm induction, and sexual differentiation. In addition to increasing virility and libido, they also increase nitrogen and water retention and stimulate skeletal growth. (MeSH)
Arsenicals definition: Inorganic or organic compounds that contain arsenic.
Arsenic Compound definition: A white, odorless, inorganic substance that contains the semi-metallic element arsenic usually in the 3 and 5-valence state, and emits toxic arsenic fumes when heated to decomposition. Arsenic compounds are primarily used in wood preservation. Exposure to this substance irritates skin and mucous membranes, and can affect the gastrointestinal tract, CNS, cardiovascular system, liver, kidneys and blood. Arsenic compounds are known human carcinogens and are associated with an increased risk of developing lung, skin, bladder, kidney, liver, prostate, digestive tract and colon cancer as well as cancer of the lymphatic and hematopoietic system. (NCI05)
azo compound definition: group of compounds containing the -N=N- group.
Benzalkonium Compounds definition: A mixture of alkylbenzyldimethylammonium compounds. It is a bactericidal quaternary ammonium detergent used topically in medicaments, deodorants, mouthwashes, as a surgical antiseptic, and as a as preservative and emulsifier in drugs and cosmetics.
Benzhydryl Compounds definition: Compounds which contain the methyl radical substituted with two benzene rings. Permitted are any substituents, but ring fusion to any of the benzene rings is not allowed.
Benzodiazepines definition: A group of two-ring heterocyclic compounds consisting of a benzene ring fused to a diazepine ring.
benzodiazepine definition: bicyclic structure consisting of fused benzene and diazepine rings; many compounds with this structure have psychotropic and neurotropic properties, and are used as sedatives, anticonvulsants, muscle relaxants, and in related applications.
Benzodiazepine definition: Drugs from this chemical class are used for their central nervous system depressant properties including sedation, facilitation of sleep, seizure control, general anesthesia, anxiolytic, amnestic, and for detoxification from similar (cross tolerant) drugs
Benzylidene Compounds definition: Compounds containing the PhCH= radical.
Bephenium Compounds definition: Analogs or derivatives of bephenium (N,N-dimethyl-N-(2-phenoxyethyl)benzenemethanaminium).
bicyclic compound definition: chemical compound containing two ring structures.
biphenyl compound definition: class of compounds containing two linked benzene rings.
Boron Compounds definition: Inorganic or organic compounds that contain boron as an integral part of the molecule.
Bridged Compounds definition: Cyclic hydrocarbons that contain multiple rings and share one or more atoms.
bridged cyclic compound definition: cyclic hydrocarbons that contain multiple rings and share one or more atoms.
Cetrimonium Compounds definition: Cetyltrimethylammonium compounds that have cationic detergent, antiseptic, and disinfectant activities. They are used in pharmaceuticals, foods, and cosmetics as preservatives; on skin, mucous membranes, etc., as antiseptics or cleansers, and also as emulsifiers. These compounds are toxic when used orally due to neuromuscular blockade.
Chromogenic Compounds definition: Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).
Dansyl Compounds definition: Compounds that contain a 1-dimethylaminonaphthalene-5-sulfonyl group.
Decamethonium Compounds definition: Compounds that contain the decamethylenebis(trimethyl)ammonium radical. These compounds frequently act as neuromuscular depolarizing agents.
Diazonium Compounds definition: The salt form of diazo compounds, compounds containing the N2 nitrogen attached to only one hydrocarbon, formulated by replacing three hydrogen atoms of the salt of an aryl primary amine by nitrogen having the general structure represented as R-N2X.
Dinitrophenyl Compounds definition: Nitroaromatic compounds containing two nitrogen groups on a phenyl ring used as pharmaceuticals, pesticides, explosives, and comprise a group of environmental pollutants.
epoxide definition: 3-membered organic ring structure containing oxygen.
Estrogens definition: Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds.
estrogen definition: hormones which stimulate the female reproductive organs, and the development of secondary female sex characteristics.
Therapeutic Estrogen definition: A class of natural or synthetic hormones that binds to a cytoplasmic receptor and initiates translocation of the hormone-receptor complex to the nucleus of target cells of tissues rich in estrogen receptors, including the endometrium, myometrium, oviduct, vagina, fallopian tube, cervix, brain, liver, placenta, ovarian cells, Leydigs cells, kidney, prostate, pancreas, heart, and skin. (NCI)
Ethylmercury Compounds definition: Organic mercury compounds in which the mercury is attached to an ethyl group.
Ferric Compounds definition: Inorganic or organic compounds containing trivalent iron.
Ferrous Compounds definition: Inorganic or organic compounds that contain divalent iron.
Heterocyclic Compounds definition: Ring compounds having atoms other than carbon in their nuclei. (Grant & Hackh's Chemical Dictionary, 5th ed)
heterocyclic compound definition: ring compounds having atoms other than carbon in their nuclei.
Hexamethonium Compounds definition: Compounds containing the hexamethylenebis(trimethylammonium) cation. Members of this group frequently act as antihypertensive agents and selective ganglionic blocking agents.
hexamethonium compound definition: compounds containing the hexamethylenebis (trimethylammonium) cation; members of this group frequently act as antihypertensive agents and selective ganglionic blocking agents.
Intercalating Agents definition: Agents that are capable of inserting themselves between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning. They are used in the study of DNA.
Oximes definition: Compounds that contain the radical R2C=N.OH derived from condensation of ALDEHYDES or KETONES with HYDROXYLAMINE. Members of this group are CHOLINESTERASE REACTIVATORS.
oxime definition: compounds containing the group C=NOH.
Pralidoxime Compounds definition: Various salts of a quaternary ammonium oxime that reconstitute inactivated acetylcholinesterase, especially at the neuromuscular junction, and may cause neuromuscular blockade. They are used as antidotes to organophosphorus poisoning as chlorides, iodides, methanesulfonates (mesylates), or other salts.
Bromine Compounds definition: Inorganic compounds that contain bromine as an integral part of the molecule.
Aluminum Compounds definition: Inorganic compounds that contain aluminum as an integral part of the molecule.
Chromium Compounds definition: Inorganic compounds that contain chromium as an integral part of the molecule.
Barium Compounds definition: Inorganic compounds that contain barium as an integral part of the molecule.
Calcium Compounds definition: Inorganic compounds that contain calcium as an integral part of the molecule.
Fluorine Compounds definition: Inorganic compounds that contain fluorine as an integral part of the molecule.
Gold Compounds definition: Inorganic compounds that contain gold as an integral part of the molecule.
Chlorine Compounds definition: Inorganic compounds that contain chlorine as an integral part of the molecule.
chemical definition: tree section heading for terms covering drugs, reagents, biomolecules, and other chemical compounds.
Chemical definition: A substance with a defined atomic or molecular structure that results from, or takes part in, reactions involving changes in its structure, composition, or properties.
chemical substance definition: A substance that is fully defined by an organic or inorganic chemical formula, includes mixtures of other chemical substances. Refine using, e.g., IUPAC codes.
Cadmium Compounds definition: Inorganic compounds that contain cadmium as an integral part of the molecule.
Cadmium Compound definition: An inorganic substance that contains the metallic element cadmium usually in its positive-2 valence state and forms toxic fumes of cadmium oxide when heated. Cadmium compounds are used in industry in electroplating and coating, in pigments, in batteries, in alloys, and as stabilizers. Exposure to these substances affects the lungs and kidneys and is associated with an increased risk of developing lung cancer. (NCI05)
Acetogenins definition: Polyketides of up to a few dozen carbons in length, formed by chain extension of multiple PROPIONATES and oxygenated to form tetrahydrofuran and lactone rings along the length of the chain. They are found in ANNONACEAE and other PLANTS. Related compounds cyclize to MACROLIDES.
Diazoamino Compounds definition: Compounds with three contiguous nitrogen atoms in linear format R2N-N=NR.
Aromatic Compounds definition: Historically, the term "aromatic" originally referred to the smell of selected compounds that later were found to contain benzene or fused benzene rings in the structure. In a structural sense, it designates compounds that, in accordance with the theory of Huckel, have a cyclic, delocalized (4n+2) pi-electron system. This includes arenes and their substitution products (e.g., benzene, naphthalene, toluene). The term has been generalized to include aromatic heterocyclic structures, such as thiophene and pyridine, but it is more precise to call compounds of the latter type heteroaromatic.
Crown Compounds definition: Macrocyclic compounds analogous to CROWN ETHERS but which lack any OXYGEN atoms.
Benzylammonium Compounds definition: QUATERNARY AMMONIUM COMPOUNDS based on BENZYLAMINES with the general formula phenyl-CN+R3.
Azabicyclo Compounds definition: Bicyclic bridged compounds that contain a nitrogen which has three bonds. The nomenclature indicates the number of atoms in each path around the rings, such as [2.2.2] for three equal length paths. Some members are TROPANES and BETA LACTAMS.