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charge coupled device camera definition: two-dimensional array of semiconductor photosensors capable of detecting and recording images by direct transduction of incident photons into electrical signals; used in a variety of image-processing systems requiring sensitivity, fast linear response, wavelength discrimination, and digital coding.
Receptors, G-Protein-Coupled definition: The largest family of cell surface receptors involved in SIGNAL TRANSDUCTION. They share a common structure and signal through HETEROTRIMERIC G-PROTEINS.
G Protein-Coupled Receptor definition: Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor.
G-Protein-Coupled Receptor Kinases definition: A family of serine-threonine kinases that are specific for G-PROTEIN-COUPLED RECEPTORS. They are regulatory proteins that play a role in G-protein-coupled receptor densensitization.
G protein coupled receptor kinase definition: serine and threonine protein kinases that specifically recognize activated G protein coupled receptor proteins.
CX3C Chemokine Receptor 1 definition: Up-regulated by chronic inflammation and encoded by human CX3CR1 Gene (CCR Family, Rhodopsin Family), 355-amino acid 40.4-kD high-affinity Fractalkine Receptor is a seven transmembrane protein expressed in brain, peripheral blood leukocytes, and spleen as a regulator of leukocyte endothelial trafficking: chemotaxis, cell migration, and adhesion. CX3CR1 signals through a pertussis toxin sensitive G-protein to induce migration and contains common GPCR features. Tyrosine sulfation enhances fractalkine-induced cell adhesion. Sharing the CX3C motif, RSV G glycoprotein can use CX3CR1 as a receptor. CX3CR1 may be an HIV envelope protein co-receptor with CD4. Homozygous CX3CR1 I249/M280 haplotype enhances infection and progression to AIDS. (from LocusLink, Swiss-Prot, OMIM, and NCI)
CX3C Chemokine Receptor 1 definition: CX3C chemokine receptor 1 protein (355 aa, 40 kD) is a cell defense protein that is encoded by the human CX3CR1 gene and has roles in cell adhesion, chemotaxis, cell defense response and signal transduction.
G-protein coupled photoreceptor activity definition: A G-protein coupled receptor that responds to incidental electromagnetic radiation, particularly visible light. [GOC:dph, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
G-protein coupled receptor activity definition: A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers. [GOC:dph, GOC:tb, http://www.iuphar-db.org]
Class A G-protein coupled receptor definition: OBSOLETE. A G-protein coupled receptor that is structurally/functionally related to the rhodopsin receptor. [GOC:dph, GOC:mah, GOC:tb, IUPHAR_GPCR:1505]
secondary active transmembrane transporter activity definition: Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. [GOC:mtg_transport, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology", ISBN:0815340729, PMID:10839820]
transcription-coupled nucleotide-excision repair definition: The preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the general nucleotide excision repair pathway. [PMID:10197977, PMID:11900249]
ATP hydrolysis coupled proton transport definition: The transport of protons against an electrochemical gradient, using energy from ATP hydrolysis. [GOC:mah]
electron transport coupled proton transport definition: The transport of protons against an electrochemical gradient, using energy from electron transport. [GOC:mah]
ATP synthesis coupled proton transport definition: The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. [ISBN:0716731363]
G Protein-Coupled Receptor 109B definition: G protein-coupled receptor 109B (387 aa, 44 kD) is a cell communication process protein that is encoded by the human HM74 gene and has a role in signal transduction.
ATPase activity, coupled definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive some other reaction, for example ion transport across a membrane. [EC:, GOC:jl]
ATP synthesis coupled electron transport definition: The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP. [ISBN:0716731363]
GPR109B Gene definition: This gene is involved in G protein-coupled receptor signal transduction and nicotinic acid receptor activity.
CX3CR1 Gene definition: This gene is involved in leukocyte adhesion and migration.
Receptors, Guanylate Cyclase-Coupled definition: A class of cellular membrane receptors that either have an intrinsic guanylate cyclase activity or are closely coupled to specific guanylate cyclases within the cell.
ATPase activity, coupled to movement of substances definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of a substance. [GOC:jl]
G-protein-coupled receptor binding definition: Interacting selectively with a G-protein-coupled receptor. [GOC:ceb, GOC:dph]
Receptors, CCR10 definition: CCR receptors with specificity for CHEMOKINE CCL27. They may play a specialized role in the cutaneous homing of LYMPHOCYTES.
Inductively-Coupled Plasma definition: Plasma that is produced using a torch and a radio frequency (RF) generator, wherein flowing gases are introduced into the torch, the RF field is activated and the gas in the RF coil region is made electrically conductive.
Couple definition: The act of linking together.
dopamine receptor coupled via Gs definition: Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity. [GOC:mah, ISBN:0953351033]