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1,4-alpha-Glucan Branching Enzyme definition: In glycogen or amylopectin synthesis, the enzyme that catalyzes the transfer of a segment of a 1,4-alpha-glucan chain to a primary hydroxy group in a similar glucan chain. EC
chloramphenicol acetyltransferase definition: bacterial enzyme which detoxifies the antibiotic chloramphenicol the gene therefore confers chloramphenicol resistance, which can be used as a marker or selector in genetic transfection experiments.
Chloramphenicol O-Acetyltransferase definition: An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC
Chloramphenicol O-acetyltransferase definition: Bacterial chloramphenicol-O-acetyltransferase protein (219 aa, 26 kD) is encoded by the bacterial chloramphenicol-O-acetyltransferase (cat) gene. This enzyme detoxifies the antibiotic chloramphenicol via acetylation to yield chloramphenicol 3-acetate. The presence of this enzyme confers chloramphenicol resistance to bacteria, which is used as a marker for selection in molecular techniques that utilize genetic transfection.
Coenzymes definition: Small molecules that are required for the catalytic function of ENZYMES. Many VITAMINS are coenzymes.
coenzyme analog definition: synthetic or natural chemical compounds which resemble naturally occurring coenzymes in structure and/or function.
enzyme electrode definition: combination of any electrochemical probe with a thin layer (10 - 200mm) of immobilized enzyme; in these devices, the function of the enzyme is to provide selectivity by virtue of its biological affinity for a particular substrate molecule.
Enzyme Activation definition: Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1, activation by ions (activators); 2, activation by cofactors (coenzymes); and 3, conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme.
Enzymes definition: Biological molecules that possess catalytic activity. They may occur naturally or be synthetically created. Enzymes are usually proteins, however CATALYTIC RNA and CATALYTIC DNA molecules have also been identified.
enzyme definition: protein molecules that possess catalytic activity; they may occur naturally or be synthetically created; for catalytic RNA use RIBOZYME.
enzyme definition: A protein that speeds up chemical reactions in the body.
Enzyme definition: Molecules that catalyze a chemical reaction. They are usually proteins, although catalytic RNA and DNA molecules have been identified.
Diacylglycerol O-Acyltransferase definition: An enzyme that catalyses the last step of the TRIACYLGLYCEROL synthesis reaction in which diacylglycerol is covalently joined to LONG-CHAIN ACYL COA to form triglyceride. It was formerly categorized as EC
Aldo-Keto Reductase 7 definition: Encoded by human oncogene AKR7A2 Gene, widely expressed 330-amino acid 36.6 kD AFAR polypeptide (Aldo/Keto Reductase 2 Family) is similar to rat Afar, to a Shaker-related voltage-gated potassium channel, and to aldose reductase. Aldoketoreductases (AKRs) detoxify aldehydes and ketones; AFAR is the principal liver reductase for 2-carboxybenzaldehyde and can metabolize Aflatoxin B1 protein-binding dihydrodiol. AFAR may protect the liver against the toxic and carcinogenic effects of Aflatoxin B1. (OMIM, Swiss-Prot, and NCI)
Enzyme Activators definition: Compounds or factors that act on a specific enzyme to increase its activity.
Nitric Oxide Synthase Type III definition: A CALCIUM-dependent, constitutively-expressed form of nitric oxide synthase found primarily in ENDOTHELIAL CELLS.
malate dehydrogenase (decarboxylating) activity definition: Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+. Does not decarboxylate oxaloacetate. [EC:]
debranching enzyme definition: OBSOLETE (was not defined before being made obsolete). [GOC:jl]
Deubiquitinating Enzyme definition: Deubiquitinating Enzymes are hydrolases that catalyze cleavage of ubiquitinated substrates with addition of H2O at the point of cleavage. Protein ubiquitination regulates the half-lives of many proteins by targeting them for degradation. Ubiquitination and deubiquitination enzymes participate in highly regulated protein degradation, chromatin remodeling, heat shock, cell cycle progression, differentiation, antigen presentation, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis.
Enzyme Unit definition: A unit of catalytic activity measurement defined as the quantity of a particular enzyme that catalyzes the transformation of one micromole of the substrate per minute under standard conditions for specified assay system. The usage of this unit is discouraged in favor of the katal by International Federation of Clinical Chemistry and Laboratory Medicine due to lack of its coherence with the SI system. One enzyme unit is equal to 16.667 nanokatals.
Enzyme Assays definition: Methods used to measure the relative activity of a specific enzyme or its concentration in solution. Typically an enzyme substrate is added to a buffer solution containing enzyme and the rate of conversion of substrate to product is measured under controlled conditions. Many classical enzymatic assay methods involve the use of synthetic colorimetric substrates and measuring the reaction rates using a spectrophotometer.
enzyme definition: Enzyme.
Enzym definition: [1] ein Protein, das als Katalysator fungiert, also chemische Reaktionen beschleunigt oder überhaupt erst ermöglicht
Ferment definition: [1] Biologie, veraltet: Substanz, die im pflanzlichen, tierischen und menschlichen Organismus gebildet wird und bestimmte chemische Umwandlungen im Körper beschleunigt [2] übertragen: vorwärtstreibendes, beschleunigendes, gärendes Element
enzyme definition: [1] Enzym
enzyme definition: Molécule ou ensemble de molécules (protéines, ou ARN) qui catalysent des réactions chimiques biologiques, donnant un ou des produits à partir d’un ou de plusieurs substrats.
enzima definition: [1] das Enzym