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Epilepsies, Partial definition: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
Focal Dermal Hypoplasia definition: A genetic skin disease characterized by hypoplasia of the dermis, herniations of fat, and hand anomalies. It is found exclusively in females and transmitted as an X-linked dominant trait.
Goltz-Gorlin syndrome definition: Multiple abnormalities with a variable expression consisting mainly of asymmetry of the face, trunk, and extremities; atrophy, telangiectasia, pigmentation disorders, and localized fat deposits in the skin; multiple mucous and perioral papillomas; and skeletal abnormalities involving the extremities. Mild mental deficiency occurs in about 15%.
Focal Infection, Dental definition: Secondary or systemic infections due to dissemination throughout the body of microorganisms whose primary focus of infection lies in the periodontal tissues.
Partial Motor Seizure definition: A simple partial seizure consisting of clonus or spasm of a muscle or muscle group; it may be single or in a continuous and repetitive series or may spread to adjacent muscles.
Seizures, Focal Motor definition: A simple partial seizure consisting of clonus or spasm of a muscle or muscle group; it may be single or in a continuous and repetitive series or may spread to adjacent muscles.
Epilepsy, Partial, Motor definition: A disorder characterized by recurrent localized paroxysmal discharges of cerebral neurons that give rise to seizures that have motor manifestations. The majority of partial motor seizures originate in the FRONTAL LOBE (see also EPILEPSY, FRONTAL LOBE). Motor seizures may manifest as tonic or clonic movements involving the face, one limb or one side of the body. A variety of more complex patterns of movement, including abnormal posturing of extremities, may also occur.
Glomerulonephritis, IGA definition: A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE.
IgA nephropathy definition: most common cause of primary glomerular disease in Europe, Australia, and United States; lesions formed as a consequence of mesangial formations of immune deposits composed of IgA.
Glomerulosclerosis, Focal Segmental definition: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.
focal definition: In terms of cancer, limited to a specific area.
Focus definition: Area of greatest concentration, attention, or activity; a central point or locus, especially of an infection.
Focal Epithelial Hyperplasia definition: Hyperplasia of the mucous membrane of the lips, tongue, and less commonly, the buccal mucosa, floor of the mouth, and palate, presenting soft, painless, round to oval sessile papules about 1 to 4 mm in diameter. The condition usually occurs in children and young adults and has familial predilection, lasting for several months, sometimes years, before running its course. A viral etiology is suspected, the isolated organism being usually the human papillomavirus. (Jablonski, Illustrated Dictionary of Dentistry; Belshe, Textbook of Human Virology, 2d ed, p954)
geleophysic dysplasia definition: A syndrome characterized by a smiling or happy facial expression (hence the adjective "geleophysic" from Greek gelios, laughing + physis, nature), short stature, brachydactyly, and dysostosis multiplex-like changes in the hands and feet. Infiltration of heart valves and liver with mucopolysaccharide-like substance has been demonstrated in some patients. Mild developmental delay is associated in some cases, but speech retardation may be attributed to hearing problems. Psychomotor retardation is an occasional feature.
CAMERA, FOCAL SPOT, RADIOGRAPHIC definition: A radiologic quality assurance instrument is a device intended for medical purposes to measure a physical characteristic associated with another radiologic device.
partial seizure definition: any seizure due to a lesion in a specific, known area of the cerebral cortex; symptoms vary with different lesion locations.
Seizures, Focal definition: Partial seizure.
Partial Seizure definition: A transitory alteration in movement, sensation or autonomic nerve function due to abnormal electric activity in a localized area of the cerebral cortex, usually without change in awareness or alertness. Symptoms vary with different lesion locations and may include but not limited to the motor (e.g. rhythmic muscle contractions in one area of the body), somatosensory and sensory alterations manifested by abnormal numbness, paresthesias or other hallucinations, including several types of aura; autonomic and psychic symptoms, e.g. with changes in speech, thought, personality, mood, sensation of deja vu or hallucinations.
Gomez and Lopez-Hernandez syndrome definition: Ectodermal dysplasia with focal involvement of the skin and nervous system in association with skull abnormalities, facial deformities, short stature, mental deficiency, genital defects, and other disorders. The syndrome is rare and all thus far reported cases have been sporadic.
focal adhesion definition: Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments. [ISBN:0124325653, ISBN:0815316208]
Focal Adhesions definition: An anchoring junction of the cell to a non-cellular substrate. It is composed of a specialized area of the plasma membrane where bundles of MICROFILAMENTS terminate and attach to the transmembrane linkers, INTEGRINS, which in turn attach through their extracellular domains to EXTRACELLULAR MATRIX PROTEINS.
focal adhesion formation definition: The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity. [GOC:jic, GOC:mah]
Focal Pattern definition: A morphologic architectural pattern in which a cellular population is distributed in a localized or relatively uneven fashion throughout a specified tissue area; not diffuse.
Brennweite definition: [1] Optik: Abstand des Brennpunkts von der Hauptebene eines optischen Systems
fokal definition: [1] Medizin: zum Herd gehörend; vom Krankheitsherd ausgehend oder den Krankheitsherd betreffend [2] Physik: auf den Brennpunkt oder die Brennweite bezogen
Brennpunkt definition: [1] Physik: Punkt, in dem eine optische Linse oder ein Hohlspiegel alle parallelen Lichtstrahlen sammelt [2] Chemie: die Temperatur, bei der sich ein Stoff entzündet