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Epistasis, Genetic definition: A form of gene interaction whereby the expression of one gene interferes with or masks the expression of a different gene or genes. Genes whose expression interferes with or masks the effects of other genes are said to be epistatic to the effected genes. Genes whose expression is affected (blocked or masked) are hypostatic to the interfering genes.
Genes definition: Specific sequences of nucleotides along a molecule of DNA (or, in the case of some viruses, RNA) which represent functional units of HEREDITY. Most eukaryotic genes contain a set of coding regions (EXONS) that are spliced together in the transcript, after removal of intervening sequence (INTRONS) and are therefore labeled split genes.
gene definition: segment of the genome that codes for a functional product.
gene definition: The functional and physical unit of heredity passed from parent to offspring. Genes are pieces of DNA, and most genes contain the information for making a specific protein.
Gene definition: A functional unit of heredity which occupies a specific position (locus) on a particular chromosome, is capable of reproducing itself exactly at each cell division, and directs the formation of a protein or other product.
Genes, vif definition: DNA sequences that form the coding region for the vif (virion infectivity factor) protein that is important for the generation of infectious virions in human immunodeficiency virus (HIV). The former name of this gene was sor (short open reading frame).
ABCB1 Gene definition: This gene plays a role in multi-drug resistance and is involved in blood-brain barrier transport.
ABCC1 Gene definition: This gene plays a role in multi-drug resistance and organic anion transport.
ABCB6 Gene definition: This gene is involved in multi-drug resistance, antigen presentation and is postulated to play a role in mitochondrial function.
ABCB5 Gene definition: This gene plays a role in both membrane transport and drug resistance.
WAS Gene definition: This gene is involved in signal transduction and plays a role in cell communication and organization.
RevM10 gene/polAS gene definition: Retroviral based anti-HIV-1 transduction construct. RevM10, a dominant negative mutant of the HIV-1 Rev gene, abolishes the wild-type Rev function and inhibits viral replication in HIV-infected T cell lines and primary T cells in vivo. PolAS is an antisense RNA complementary to human HIV-1 pol gene and is capable of interfering with HIV polymerase gene expression. Co-administration of both gene constructs allows high efficiency in blocking propagation of HIV.
ATM wt Allele definition: Human ATM wild-type allele is located within 11q22-q23 and is approximately 143 kb in length. This allele, which encodes serine-protein kinase ATM protein, plays a critical role in cell cycle checkpoint signaling pathways required for cellular response to DNA damage and maintenance of genomic stability. Defects in the ATM gene cause ataxia telangiectasia and contribute to certain cancers such as T-cell acute lymphoblastic leukemia, B-cell chronic lymphocytic leukemia and B-cell non-Hodgkin lymphomas.
Gene_Product_Encoded_By_Gene definition: This role asserts the connection between a gene product and the gene that encodes it. Since a protein can only be encoded by a single gene this is considered a defining role. The domain and range kind for this role are Gene_Product_Kind and Gene_Kind, respectively.
HTR2A wt Allele definition: Human HTR2A wild-type allele is located within 13q14-q21 and is approximately 63 kb in length. This allele, which encodes 5-hydroxytryptamine 2A receptor protein, is involved in several processes that activate a PI-calcium second messenger system via G-protein association, such as tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
gene definition: [1] das Gen
gene definition: Gène.
befangen definition: [1] nicht mehr neutral sondern jemanden verpflichtet [2] gehemmt, unsicher, verlegen, verwirrt
Gen definition: [1] Biologie / Vererbungslehre: Sequenz auf der DNA, die mit einer bestimmten Basenabfolge ein bestimmtes Protein codiert.
betreten definition: [1] in einen Raum gehen [2] auf eine Fläche steigen
gène definition: [1] Gen
gène definition: Unité de base de l’information qui se transmet de génération en génération. Un '''gène''' se transmet à la génération suivante en apportant ses caractèristiques qui s’expriment ou pas en fonction de l’environnement dans lequel il se trouve.
assujettissement definition: Action d'assujettir, de soumettre, de conquérir.
assujettissement definition: État de soumission, de dépendance.
assujettissement definition: Contrainte, obligation de faire une chose.
honte definition: Déshonneur, opprobre, humiliation (ce qui est le sens étymologique et ancien).
honte definition: ''Être la '''honte''', faire la '''honte''' de sa famille, de son pays, de son siècle'' : Lui faire un grand déshonneur.
honte definition: ''À la '''honte''' de'' : En causant déshonneur.
honte definition: #* ''C’est une '''honte''', c’est grand'honte, il ne convient pas, il est messéant.''
honte definition: Se dit aussi au pluriel (Voltaire a condamné cet emploi ; mais, outre les autorités, la raison et l’usage n'empêchent pas d’employer ce mot abstrait au pluriel).
honte definition: #* ''Faire mille '''hontes''', faire cent '''hontes''', accabler d’outrages.''
honte definition: Sentiment pénible qu’excite dans l’âme la pensée ou la crainte du déshonneur.
honte definition: ''Faire '''honte''' : Éclipser.
honte definition: ''Faire '''honte''''' : Faire des reproches qui causent de la honte, de la confusion.
honte definition: ''Vous devriez mourir de '''honte''''' : Se dit, par exagération, à quelqu'un qui a commis une action très répréhensible.
honte definition: ''Avoir perdu toute '''honte''''' : Être insensible au déshonneur.
honte definition: On dit dans le même sens : ''mettre bas toute '''honte''''', et ''avoir toute '''honte''' bue''.
honte definition: ''Courte '''honte''''' : Insuccès.
honte definition: ''Mauvaise '''honte''''' : Fausse honte de ce qui n'est pas blâmable, et quelquefois même de ce qui est louable.
honte definition: ''Fausse '''honte''''', ou ''sotte '''honte''''' : Timidité mal placée, honte non justifiée.
honte definition: Dans le langage biblique, les parties que l’on doit cacher.
gêne definition: Ce qui met à l’étroit, mal à l’aise, ce qui empêche d’agir librement.
gêne definition: Embarras que cause le séjour d’une personne chez une autre.
gêne definition: Contrainte fâcheuse, état pénible où l’on se trouve.
gêne definition:
gêne definition: Pénurie d’argent, état voisin de la pauvreté.
gêné definition: Quelqu’un qui éprouve de la gêne, de la honte.
gene definition: [1] das Gen
gene definition: Gène.
hinder definition: Inconvénient.
hinder definition: Embarras.
gene definition: Gène.
gene definition: Gène.