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Definition
 
enEnglish
hand definition: part of the upper limb distal to the wrist including carpus, metacarpus and fingers.
HAND definition: The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits. (NCI)
Hand definition: The distal portion of the upper extremity. It consists of the carpus, metacarpus, and digits.
Hand Bones definition: The CARPAL BONES; METACARPAL BONES; and FINGER PHALANGES. In each hand there are eight carpal bones, five metacarpal bones, and 14 phalanges.
EF Hand Motifs definition: Calcium-binding motifs composed of two helixes (E and F) joined by a loop. Calcium is bound by the loop region. These motifs are found in many proteins that are regulated by calcium.
EF-Hand Domain definition: Forming a single Ca2+-binding site in many calcium-binding proteins, the basic EF-Hand Domain consists of a conserved 12-residue loop region between two perpendicular 10-12 residue alpha helices (helix-loop-helix). Ca2+ interacts with loop residues in a pentagonal bipyramidal configuration; each loop residue is important for Ca2+ coordination. Loop residues 1, 3, 5, 7, 9, and 12 (invariant Glu or Asp) are directly necessary for Ca2+ binding. Amino-acid variations at positions 1, 3, 5, 7, and 9 alter ion affinity. Single or multiple domains cause structural/functional variations. EF-hand Proteins are grouped into either regulatory/signaling or structural/buffering/transport categories. Ca2+ binding to regulatory proteins induces conformational/functional change; Ca2+ binding to structural proteins seems to provide a Ca2+ buffer. (NCI)
 
 
deGerman
beidhändig definition: [1a] als Adjektiv: an beiden Händen [1b] als Adverb: mit beiden Händen (gleichzeitig)