dict.md logo
Choose languages of interest
SELECT >>
English
Advertisement:
Definition
 
enEnglish
Carboxylic Ester Hydrolases definition: Enzymes which catalyze the hydrolysis of carboxylic acid esters with the formation of an alcohol and a carboxylic acid anion.
Epoxide Hydrolases definition: Enzymes that catalyze reversibly the formation of an epoxide or arene oxide from a glycol or aromatic diol, respectively.
epoxide hydrolase definition: catalyzes the hydrolysis of the ether function of epoxides to glycol important in eicosanoid metabolism, detoxication of mutagens, and other processes.
glycosidase definition: covering the sugar hydrolases.
Hydrolases definition: Any member of the class of enzymes that catalyze the cleavage of the substrate and the addition of water to the resulting molecules, e.g., ESTERASES, glycosidases (GLYCOSIDE HYDROLASES), lipases, NUCLEOTIDASES, peptidases (PEPTIDE HYDROLASES), and phosphatases (PHOSPHORIC MONOESTER HYDROLASES). EC 3.
Hydrolase definition: Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage; e.g., esterases, phosphatases, nucleases, peptidases. SYN hydrolyzing enzymes.
Monoacylglycerol Lipases definition: An enzyme that catalyzes the hydrolysis of glycerol monoesters of long-chain fatty acids EC 3.1.1.23.
Nucleosidases definition: N-GLYCOSYL HYDROLASES that catalyze the hydrolysis of the N-glycosidic bond of nucleoside-linked sugars.
Peptide Hydrolases definition: Hydrolases that specifically cleave the peptide bonds found in PROTEINS and PEPTIDES. Examples of sub-subclasses for this group include EXOPEPTIDASES and ENDOPEPTIDASES.
proteolytic enzymes definition: Enzymes produced and secreted by the pancreas which aid in the proteolysis of proteins in the digestive tract. Pancreatic proteolytic enzymes include trypsin, chymotrypsin and carboxypeptidase; these enzymes are secreted as zymogens, inactive precursors of the enzymes, and are activated in the lumen of the digestive canal. Another proteolytic enzyme, enteropeptidase, is associated with the brush border of enterocytes; this enzyme catalyses the conversion of trypsinogen into trypsin which, in turn, can activate a number of other pancreatic zymogens. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43492&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43492&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C38728" NCI Thesaurus)
Proteolytic Enzymes definition: Enzymes produced and secreted by the pancreas which aid in the proteolysis of proteins in the digestive tract. Pancreatic proteolytic enzymes include trypsin, chymotrypsin and carboxypeptidase; these enzymes are secreted as zymogens, inactive precursors of the enzymes, and are activated in the lumen of the digestive canal. Another proteolytic enzyme, enteropeptidase, is associated with the brush border of enterocytes; this enzyme catalyses the conversion of trypsinogen into trypsin which, in turn, can activate a number of other pancreatic zymogens. (NCI04)
Phosphoric Diester Hydrolases definition: A class of enzymes that catalyze the hydrolysis of one of the two ester bonds in a phosphodiester compound. EC 3.1.4.
Phosphoric Monoester Hydrolases definition: A group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate. EC 3.1.3.
phosphomonoesterase definition: a group of hydrolases which catalyze the hydrolysis of monophosphoric esters with the production of one mole of orthophosphate.
Phosphatase definition: A class of enzymes that catalyze the removal of phosphate groups from their substrates.
Serine Endopeptidases definition: Any member of the group of ENDOPEPTIDASES containing at the active site a serine residue involved in catalysis.
Serine Protease definition: Proteases that have a serine residue in the active center of the enzyme. These enzymes catalyze the hydrolysis of covalent peptidic bonds by serine nucleophilic attack. Serine proteases participate in a wide range of functions in the body, including blood clotting, inflammation, and digestion.
Xylosidases definition: A group of enzymes that catalyze the hydrolysis of alpha- or beta-xylosidic linkages. EC 3.2.1.8 catalyzes the endo-hydrolysis of 1,4-beta-D-xylosidic linkages; EC 3.2.1.32 catalyzes the endo-hydrolysis of 1,3-beta-D-xylosidic linkages; EC 3.2.1.37 catalyzes the exo-hydrolysis of 1,4-beta-D-linkages from the non-reducing termini of xylans; and EC 3.2.1.72 catalyzes the exo-hydrolysis of 1,3-beta-D-linkages from the non-reducing termini of xylans. Other xylosidases have been identified that catalyze the hydrolysis of alpha-xylosidic bonds.
Acid Anhydride Hydrolases definition: A group of enzymes that catalyze the hydrolysis of diphosphate bonds in compounds such as nucleoside di- and tri-phosphates, and sulfonyl-containing anhydrides such as adenylylsulfate. (Enzyme Nomenclature, 1992) EC 3.6.
acid anhydride hydrolase definition: heading term for the high energy phosphatases.
N-Glycosyl Hydrolases definition: A class of enzymes involved in the hydrolysis of the N-glycosidic bond of nitrogen-linked sugars.
epoxide hydrolase activity definition: Catalysis of the reaction: an epoxide + H2O = a glycol. [EC:3.3.2.10]
lipid-phosphate phosphatase activity definition: Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H2O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate. [EC:3.1.3.76]
Phosphoric Triester Hydrolases definition: A class of enzymes that catalyze the hydrolysis of one of the three ester bonds in a phosphotriester-containing compound.
Serine Proteases definition: Peptide hydrolases that contain at the active site a SERINE residue involved in catalysis.