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Embryo, Nonmammalian definition: The developmental entity of a fertilized egg (ZYGOTE) in animal species other than MAMMALS. For chickens, use CHICK EMBRYO.
Uterine tube definition: Organ with organ cavity which connects the uterine cavity to the peritoneal cavity. Examples: There are only two uterine tubes, the right and the left uterine tubes.
Fallopian Tubes definition: A pair of highly specialized muscular canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM collection, and the site for the final maturation of gametes and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.
fallopian tube definition: pair of highly specialized muscular canals extending from the uterus to its corresponding ovary; provide the means for ovum collection, and the site for the final maturation of gametes and fertilization; the fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae; its wall consists of three histologic layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells.
fallopian tubes definition: (fa-LO-pee-in) Part of the female reproductive tract. The long slender tubes through which eggs pass from the ovaries to the uterus.
Uterine tube definition: Organ with organ cavity which connects the uterine cavity to the peritoneal cavity. Examples: There are only two uterine tubes, the right and the left uterine tubes.
FALLOPIAN TUBE definition: One of a pair of tubes that extend from the uterus to each of the ovaries. Following ovulation the egg travels down the fallopian tube to the uterus where fertilization may or may not occur. (NCI)
Oviduct definition: The tubular tract in female animals through which eggs are discharged either to the exterior or, in mammals, to the uterus.
Fallopian Tube definition: One of a pair of tubes that extend from the uterus to each of the ovaries. Following ovulation the egg travels down the fallopian tube to the uterus where fertilization may or may not occur.
Mammals definition: Warm-blooded vertebrate animals belonging to the class Mammalia, including all that possess hair and suckle their young.
Mammalia definition: warm-blooded chordates with hair, 7 cervical vertebrates, 4 chambered heart, 5 or fewer digits on each limb, mammary glands with milk for feeding young; can be terrestrial, aerial or aquatic.
Mammal definition: Any warm-blooded vertebrate having the skin more or less covered with hair; young are born alive except for the small subclass of monotremes and nourished with milk.
Pregnancy definition: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
PREGNANCY definition: Pregnancy is the state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth. (NCI)
pregnancy definition: condition of having a developing embryo or fetus in the body.
Pregnancy definition: Period from conception to childbirth.
female pregnancy definition: The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. [ISBN:0192800825]
Pregnancy definition: The state or condition of having a developing embryo or fetus in the body (uterus), after union of an ovum and spermatozoon, during the period from conception to birth.
gastrin releasing peptide definition: mammalian homolog of bombesin; widely distributed in GI tract and CNS; also expressed in fetal lung tissue and by small cell lung carcinomas.
Gastrin-Releasing Peptide definition: Neuropeptide and gut hormone that helps regulate GASTRIC ACID secretion and motor function. Once released from nerves in the antrum of the STOMACH, the neuropeptide stimulates release of GASTRIN from the GASTRIN-SECRETING CELLS.
Gastrin Releasing Peptide definition: Gastrin-releasing peptide (GRP) is the equivalent in mammals of the amphibian bombesin. Infusion of either GRP or bombesin increases plasma levels of gastrin, pancreatic polypeptide, glucagon, gastric inhibitory peptide, and insulin. It is widely distributed in the gastrointestinal tract and in the nervous system. In normal adult mammal GRP is strictly a neuropeptides and functions in a neurotransmitter-like fashion. In the fetus, a larger form of GRP acts as a hormone and exerts growth factor-like activity on many organs, aiding in development.
superior colliculus definition: either of the superior (rostral) pair of rounded eminences symmetrically located in the tectum of the mesencephalon, containing reflex centers for visual sensations.
Superior Colliculi definition: The anterior pair of the quadrigeminal bodies which contain the centers for visual function.
mammalian embryology definition: study of the formation and development of mammalian embryos.
Guanine Nucleotide-Releasing Factor 2 definition: A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.
Ephrin-A2 definition: A GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR-containing ephrin with a high affinity for the EPHA3 RECEPTOR. Early in embryogenesis it is expressed at high levels in the MESENCEPHALON; SOMITES; branchial arches, and LIMB BUDS.
Baculoviral IAP Repeat-Containing Protein 3 definition: Encoded by BIRC3 Gene (IAP Family) Baculoviral IAP Repeat-Containing Protein 3 inhibits apoptosis by binding to TNF Receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. BIRC3 inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring-type zinc finger domain while the Zn binding domain is involved in protein-protein interactions in caspase inhibition and spindle assembly. BIRC3 is present in many fetal and adult tissues and mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
Chromosomes, Artificial, Mammalian definition: DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful replication, propagation to and maintainance in progeny mammalian cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
Orthoreovirus, Mammalian definition: A species of ORTHOREOVIRUS infecting mammals (other than baboons). There are four serotypes. In humans they are generally benign but may sometimes cause upper respiratory tract illness or enteritis in infants and children. MAMMALIAN ORTHOREOVIRUS 3 is a very pathogenic virus in laboratory rodents.
Chromosomes, Mammalian definition: Complex nucleoprotein structures which contain the genomic DNA and are part of the CELL NUCLEUS of MAMMALS.
distinct antral spaces stage, oogenesis definition: The stage in oogenesis when the antral spaces become distinct and the first polar body forms. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
double layer follicle stage, oogenesis definition: The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
fused antrum stage, oogenesis definition: The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
mature follicle stage, oogenesis definition: The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
multi-layer follicle stage, oogenesis definition: The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
oogonium stage, oogenesis definition: The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
primary follicle stage, oogenesis definition: The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
primary oocyte stage, oogenesis definition: The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
scattered antral spaces stage, oogenesis definition: The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration. [GOC:jic, GOC:mtg_sensu, ISBN:0198542771]
BIRC2 Gene definition: This gene is a potent inhibitor of apoptosis and plays an important role in apoptotic signal transduction.
BIRC3 Gene definition: This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
mSin3 definition: Important in eukaryotic gene regulation, histone acetylation and deacetylation are catalyzed by histone deacetylase complexes that include SAP30, SAP18, histone deacetylases, histone-binding proteins and other proteins. SAP18 interacts with SIN3 and enhances SIN3-mediated transcriptional repression. Gene-specific targeting of the SIN3 co-repressor complex by DNA-bound repressors is important in eukaryotic gene silencing. The SIN3 co-repressor specifically associates with some transcriptional repressors, including members of the MAD family important in development. The PAH2 domain of SIN3A interacts with the transrepression domain (SID) of MAD1. MAD-MAX complexes repress transcription through recruitment of SIN3 co-repressor. The MXI1 protein family functions as potent antagonists of MYC oncoproteins. They compete with MYC for the protein MAX and for consensus DNA binding sites and to recruit SIN3 proteins and their associated co-repressors. (NCI)
BIRC4 Gene definition: This gene is involved in apoptotic regulation through caspase interaction.
ENAH Gene definition: This gene is involved in the regulation of cytoskeletal structure.
Mammalian Cell definition: A cell originating from or isolated from an animal of class Mammalia.
Mammalian Genetics definition: The branch of science concerned with the means and consequences of transmission and generation of the components of biological inheritance in animals of the class Mammalia.
Baculoviral IAP Repeat-Containing Protein 2 definition: Encoded by BIRC2 Gene (IAP Family), Baculoviral IAP Repeat-Containing Protein 2 inhibits apoptosis by binding to TNF Receptor-associated factors TRAF1 and TRAF2 preventing activation of ICE-like proteases. BIRC2 inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain.
BIRC3 wt Allele definition: Human BIRC3 wild-type allele is located in the vicinity of 11q25 and is approximately 14 kb in length. This allele, which encodes baculoviral IAP repeat-containing protein 3, is involved in apoptotic inhibition by serum deprivation.
BIRC2 wt Allele definition: Human BIRC2 wild-type allele is located in the vicinity of 11q22 and is approximately 30 kb in length. This allele, which encodes baculoviral IAP repeat-containing protein 2, plays a role in the inhibition of apoptosis through caspase inactivation.
Embryo, Mammalian definition: The entity of a developing mammal (MAMMALS), generally from the cleavage of a ZYGOTE to the end of embryonic differentiation of basic structures. For the human embryo, this represents the first two months of intrauterine development preceding the stages of the FETUS.
Embryonic Structures, Mammalian definition: The anatomical parts that make up a mammalian organism in the early stages of development.
Embryonic Structures, Nonmammalian definition: The anatomical parts of a non-mammalian animal during its early stages of development.