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Multiple Myeloma definition: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
multiple myeloma definition: malignant neoplasm of plasma cells usually arising in the bone marrow and manifested by skeletal destruction, bone pain, and the presence of anomalous immunoglobulins.
myeloma definition: (mye-eh-LO-ma) Cancer that arises in plasma cells (white blood cells that produce antibodies).
Plasma Cell Myeloma definition: A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)
Pregnancy, Multiple definition: The condition of bearing two or more FETUSES simultaneously. (Stedman, 25th ed)
Gastric Polyp definition: A neoplastic or non-neoplastic lesion arising from the gastric mucosa. -- 2003
Fold Change definition: An indication of the magnitude difference between two values specified as the number of multiples of the first value to the second value (e.g., from 10 to 20 is a 2-fold increase, from 10 to 50 is a five-fold increase).
Prefix for Binary Multiples definition: A prefix used in binary numeral system for denoting powers of two.