dict.md logo
Choose languages of interest
SELECT >>
English
Advertisement:
Definition
 
enEnglish
Neuropeptides definition: Peptides released by NEURONS as intercellular messengers. Many neuropeptides are also hormones released by non-neuronal cells.
neuropeptide definition: peptides released by neural tissue as intercellular messengers; many are also hormones released by non-neuronal cells.
neuropeptide definition: A member of a class of protein-like molecules made in the brain. Neuropeptides consist of short chains of amino acids, with some functioning as neurotransmitters and some functioning as hormones.
Neuropeptide definition: Peptides with direct synaptic effects or indirect modulatory effects on the nervous system. A neuropeptide is a molecule released by neurons as an intercellular neurotransmitter. Alternatively, neuropeptides can be released by non-neuronal cells as hormones. They are endogenous peptides such as endorphins that influence neural activity or functioning.
Receptors, Neuropeptide definition: Cell surface receptors that bind specific neuropeptides with high affinity and trigger intracellular changes influencing the behavior of cells. Many neuropeptides are also hormones outside of the nervous system.
neuropeptide receptor definition: cell surface receptors that bind specific neuropeptides with high affinity and trigger intracellular changes influencing the behavior of cells.
T-Cell Antiapoptosis Pathway definition: Vasoactive intestinal peptide (VIP) and the structurally related pituitary adenylate cyclase-activating polypeptide (PACAP), two neuropeptides present in the lymphoid microenvironment, elicit a broad spectrum of biological functions, including the modulation of innate and adaptive immunity. Another important immunoregulatory function of VIP and PACAP is their inhibition effect on AICD in T cells. They inhibit the TCR-stimulated FasL expression and apoptosis of T cell through specific receptors and induction of intracellular cAMP. VIP down-regulate c-Myc synthesis, the NF-AT-dependent Egr2 and Egr3 expression, the NF-AT and NF-kB. (BioCarta)