dict.md logo
Choose languages of interest
SELECT >>
English
German
French
Portuguese
Spanish
 
Add further languages:
Add all languages
Advertisement:
Definition
 
enEnglish
Blood Platelet Disorders definition: Disorders caused by abnormalities in platelet count or function.
platelet disorder definition: disorders caused by abnormalities in platelet count or function.
thrombocytopathy definition: qualitative disorder of the blood platelets, due mainly to deficiency of platelet factor 3.
Blood Platelets definition: Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.
platelet definition: non-nucleated disk shaped cells formed in the megakaryocyte and found in the blood of all mammals; they are mainly involved in blood coagulation, and have a role in inflammation.
thrombocytes definition: Blood cells that help prevent bleeding by causing blood clots to form.
Platelet definition: An irregular, disc-shaped element in the blood that assists in blood clotting. Platelets are not blood cells, they are fragments of large bone marrow cells called megakaryocytes.
Platelet Activation definition: A series of progressive, overlapping events, triggered by exposure of the PLATELETS to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
platelet activation definition: process by which platelets change shape, aggregate, adhere to vascular wall, and secrete cytokines during clotting; induced by a variety of agonists including thrombin, ADP, PAF, and epinephrine via a G protein/IP3 coupled receptor system.
platelet activation definition: A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. [http://www.graylab.ac.uk/omd/]
Platelet Activation definition: Platelet Activation involves initiation of a set of stimulated platelet activities involved in aggregation of platelets and fibrin during blood coagulation. Containing mitochondria and granules of active enzymes, blood platelets are non-nucleated irregular disk-shaped cytoplasmic fragments of megakaryocytes and shed from the marrow sinus into the peripheral blood.
Platelet Adhesiveness definition: The process whereby PLATELETS adhere to something other than platelets, e.g., COLLAGEN; BASEMENT MEMBRANE; MICROFIBRILS; or other "foreign" surfaces.
Platelet Aggregation definition: The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.
platelet aggregation definition: attachment of platelets to one another; part of the mechanism leading to the formation of a thrombus.
platelet aggregation definition: The adhesion of one platelet to one or more other platelets via adhesion molecules. [GOC:vk]
Platelet Aggregation definition: The accumulation and adherence of platelets to form a clot or thrombus. When injury or bleeding occurs, platelets clump together at the site of injury; they expand and adhere to the injured area, thereby acting as a plug to reduce the bleeding. Platelet dysfunction can result in blood clotting and bleeding disorders.
Platelet Aggregation Inhibitors definition: Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
platelet aggregation inhibitor definition: drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
Platelet Count definition: The number of PLATELETS per unit volume in a sample of venous BLOOD.
Platelet Count definition: The determination of the number of platelets in a blood sample, usually expressed as platelets per cubic millimeter (cmm) of whole blood.
Platelet definition: A measurement of the platelets per unit of a biological specimen.
Antigens, Human Platelet definition: Human alloantigens expressed only on platelets, specifically on platelet membrane glycoproteins. These platelet-specific antigens are immunogenic and can result in pathological reactions to transfusion therapy.
Platelet Transfusion definition: The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.
platelet transfusion definition: transfer of blood platelets from a donor to a recipient or reinfusion to the donor.
Platelet Transfusion definition: The infusion of platelets into the bloodstream.
Analyzers, Laboratory, Hematology, Platelet Aggregation definition: Laboratory blood coagulation analyzers used to evaluate the adhesion of platelets to one another. These analyzers activate the aggregation process by adding an aggregating agent, such as adenosine diphosphate (ADP) or ristocetin. Platelet aggregation analyzers use optical density (turbidmetric), electrical impedance, or bioluminescence measuring methods. Usually, these analyzers require previous sample preparation, including centrifugation, to obtain platelet-rich plasma (PRP) and platelet-poor plasma (PPP) samples; but, some analyzers that use the impedance method of analysis can use whole blood. Platelet aggregation analyzers are used to distinguish between different types of platelet dysfunction (e.g., deficiency in platelet release substances, poor platelet adhesion to injured tissue).
Integrin beta3 definition: An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing and INTEGRIN ALPHAV-containing heterodimers. Integrin beta3 occurs as three alternatively spliced isoforms, designated beta3A-C.
CONTROL, PLATELET definition: A hematology quality control mixture is a device used to ascertain the accuracy and precision of manual, semiautomated, and automated determinations of cell parameters such as white cell count (WBC), red cell count (RBC), platelet count (PLT), hemoglobin, hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC).
platelet preservation definition: process by which platelets are kept viable outside of the organism from which they are derived; for example, kept from decay by means of a chemical agent, cooling, or a fluid substitute that mimics the natural state within the organism; may be for preservation to implant into an organism or for permanent preservation.
Recorders, Graphic, Platelet Aggregation definition: Graphic recorders used for continuous recording of the changes in platelet shape and platelet aggregation. These recorders are coupled to platelet aggregation analyzers to store the information according the measuring method used (e.g., optical density, electric impedance).
AGGREGROMETER, PLATELET definition: A platelet aggregometer is a device, used to determine changes in platelet shape and platelet aggregation following the addition of an aggregating reagent to a platelet rich plasma.
platelet formation definition: The process by which platelets bud from long processes extended by megakaryocytes. [GOC:mah, ISBN:0815316194]
Immature Platelet definition: A young platelet that contains residual mRNA and rRNA when released from the bone marrow into the peripheral circulation as a result of thrombopoiesis. Immature platelets normally make up a small percentage of the total circulating platelets (1.1-6.1%, with a mean of 3.4%.). An increased proportion of immature platelets in blood indicates increased thrombopoiesis. The relationship between the percent of immature platelets and the platelet count can be used to determine the rate of platelet turnover.
Alpha Granule definition: Granules found in several types of cells, especially platelets, where they are the most numerous type of granule; contain secretory proteins.
platelet degranulation definition: The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. [GOC:add]
Platelet Engraftment definition: A platelet count of 20,000 to 50,000 (platelets per microliter of blood) is a sign of platelet engraftment. For patients who receive marrow or peripheral blood cells, platelet engraftment often happens at the same time or a little bit after neutrophil engraftment. For patients who receive cord blood, it may be 8 weeks or longer after transplant before platelet engraftment occurs.
iridosome definition: A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance. [GOC:mh]
 
 
ltLithuanian
trombocitas definition: [1] Thrombozyt