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Definition
 
enEnglish
Hematopoietic Stem Cells definition: Progenitor cells from which all blood cells derive.
hematopoietic stem cell definition: progenitor cells from which all blood cells derive; a cell that can renew itself, can differentiate to a variety of specialized cells, can mobilize out of the bone marrow into circulating blood, and can undergo apoptosis.
Hematopoietic Stem Cell definition: Primitive blood cells derived from embryonic mesenchyme capable of differentiating into any of the blood cell line progenitor cells (erythroblasts, young granulocytic series cells, megakaryocytes, etc.)
Stem Cells definition: Relatively undifferentiated cells that retain the ability to divide and proliferate throughout postnatal life to provide progenitor cells that can differentiate into specialized cells.
stem cells definition: Cells from which other types of cells can develop.
stem cell definition: relatively undifferentiated cells of the same lineage that retain the ability to divide and cycle throughout postnatal life to provide cells that can become specialized and take the place of those that die or are lost.
Stem Cell definition: Relatively undifferentiated cells of the same lineage (family type) that retain the ability to divide throughout postnatal life to reproduce themselves and to give rise to other more specialized types of cells to take the place of those that die or are lost. (MeSH)
Tyrosine-Protein Kinase BTK definition: Tyrosine-protein kinase BTK (659 aa, ~76 kDa) is encoded by the human BTK gene. This protein is involved in both B-cell development and signal transduction.
Small Inducible Cytokine A23 Isoform Ckbeta8 definition: Expressed in lung, liver, skeletal muscle, bone marrow, placenta, pancreas, and fetal liver by human CCL23 Gene (Intercrine Beta Family), secreted immunoregulatory Small Inducible Cytokine A23 Isoform Ckbeta8 is a potent CCR1 receptor agonist and suppressor of progenitor cell colony formation with chemotactic activity for resting T lymphocytes, monocytes, and neutrophils in inflammatory processes.
Chemokine CCL24 definition: A CC-type chemokine with specificity for CCR3 RECEPTORS. It is a chemoattractant for EOSINOPHILS.
Small Inducible Cytokine A24 definition: Expressed in activated monocytes and activated T lymphocytes by human CCL24 Gene (Intercrine Beta Family), N-glycosylated secreted immunoregulatory Small Inducible Cytokine A24 binds to CCR3, exerts chemotactic activity on resting T lymphocytes, neutrophils, and eosinophils in inflammatory processes, and exhibits strong suppression of hematopoietic progenitor colony formation. (NCI)
Bone Marrow Myeloid Stem Cell definition: One of the two stem cells derived from hematopoietic stem cells. (MeSH)
myeloid stem cell definition: an immature cell found in the bone marrow and not normally in the peripheral blood; it is the most primitive precursor in the granulocytic series, which matures to develop into the promyelocyte and eventually the granular leukocyte; myeloblasts have fine, evenly distributed chromatin, several nucleoli, and a non-granular basophilic cytoplasm.
Myeloid Progenitor Cells definition: Stem cells derived from HEMATOPOIETIC STEM CELLS. Derived from these myeloid progenitor cells are the MEGAKARYOCYTES; ERYTHROID CELLS; MYELOID CELLS; and some DENDRITIC CELLS.
Ancestor definition: Someone from whom you are descended (but usually more remote than a grandparent).
Mesenchymal Stem Cells definition: Cells that can develop into distinct mesenchymal tissue such as BONE; TENDONS; MUSCLES; ADIPOSE TISSUE; CARTILAGE; NERVE TISSUE; and BLOOD and BLOOD VESSELS.
BTK Gene definition: This gene is involved in both signaling and B-cell development.
Progenitor Cell Engraftment definition: Establishment of a self replicating population of stem cells with subsequent repopulation of differentiated cell types.
hemopoietic progenitor cell differentiation definition: The process whereby precursor cell type acquires the specialized features of a hemopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. [GOC:add, ISBN:0781735149 "Fundamental Immunology", PMID:16551251]
myeloid progenitor cell differentiation definition: The process whereby a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages. [GOC:add, PMID:16551264]
lymphoid progenitor cell differentiation definition: The process whereby a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages. [GOC:add, PMID:16551251, PMID:16551264]
forebrain neuroblast differentiation definition: The process whereby neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate. [GO_REF:0000021, GOC:cls, GOC:dgh, GOC:dph, GOC:jic, GOC:mtg_15jun06, PMID:16226447]
Pro-B Lymphocytes definition: Cells from the stage of B LYMPHOCYTE development where B-CELL GENE REARRANGEMENT begins. The pro-B cell stage is followed by the pre-B cell stage.
Lymphoid Progenitor Cells definition: Stem cells from which B-LYMPHOCYTES; T-LYMPHOCYTES; NATURAL KILLER CELLS; and some DENDRITIC CELLS derive.
erythroid stem cell definition: erythroid stem cells derived from myeloid stem cells; the progenitor cells develop in two phases, erythroid burst-forming units (bfu-e) followed by erythroid colony-forming units (cfu-e); bfu-e differentiate into cfu-e on stimulation by erythropoietin, and then further differentiate into erythroblasts when stimulated by other factors.
Erythroid Stem Cell definition: Committed, erythroid stem cells derived from myeloid stem cells. The progenitor cells develop in two phases: erythroid burst-forming units (BFU-E) followed by erythroid colony-forming units (CFU-E). BFU-E differentiate into CFU-E on stimulation by erythropoietin, and then further differentiate into erythroblasts when stimulated by other factors. (MeSH)
Granulocyte-Macrophage Progenitor Cells definition: The parent cells that give rise to both cells of the GRANULOCYTE lineage and cells of the monocyte/macrophage lineage.
Megakaryocyte-Erythroid Progenitor Cells definition: The parent cells that give rise to both cells of the MEGAKARYOCYTE and the ERYTHROCYTE lineages.
Megakaryocyte Progenitor Cells definition: The parent cells that give rise to cells in the MEGAKARYOCYTE lineage, and ultimately BLOOD PLATELETS.
oligodendrocyte progenitor proliferation definition: The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system. [GOC:mah, GOC:sl, PMID:15504915]
progenitor definition: Ancêtre, géniteur.
progenitor definition: Auteur.
 
 
deGerman
Vorläufer definition: [1] Wegbereiter [2] Sport: jemand, der einen Bewerb vor den gewerteten Sportlern bestreitet [3] Färberwesen: Anfangs- oder Endstreifen eines Gewebebandes