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inborn renal aminoaciduria definition: inborn genetic mutations causing impairment of renal tubular transport of amino acids.
Renal Aminoacidurias definition: A group of inherited kidney disorders characterized by the abnormally elevated levels of AMINO ACIDS in URINE. Genetic mutations of transport proteins result in the defective reabsorption of free amino acids at the PROXIMAL RENAL TUBULES. Renal aminoaciduria are classified by the specific amino acid or acids involved.
Carcinoma, Renal Cell definition: A heterogeneous group of sporadic or hereditary carcinoma derived from cells of the KIDNEYS. There are several subtypes including the clear cells, the papillary, the chromophobe, the collecting duct, the spindle cells (sarcomatoid), or mixed cell-type carcinoma.
renal cell carcinoma definition: cancerous kidney tumor composed of tubular cells; usually occurs in middle age or later in life; primary symptom is hematuria; nephrectomy is usually necessary.
renal cell cancer definition: Cancer that develops in the lining of the renal tubules, which filter the blood and produce urine.
Renal Cell Carcinoma definition: A carcinoma arising from the renal parenchyma. The incidence of renal cell carcinoma has increased by 35% from 1973 to 1991. There is a strong correlation between cigarette smoking and the development of renal cell carcinoma. The clinical presentation includes : hematuria, flank pain and a palpable lumbar mass. A high percentage of renal cell carcinomas are diagnosed when an ultrasound is performed for other purposes. Diagnostic procedures include: ultra sound, intravenous pyelography and computed tomography (CT). Radical nephrectomy is the standard intervention procedure. Renal cell carcinoma is generally considered to be resistant to radiation treatment and chemotherapy.
Glycosuria, Renal definition: An autosomal inherited disorder due to defective reabsorption of GLUCOSE by the PROXIMAL RENAL TUBULES. The urinary loss of glucose can reach beyond 50 g/day. It is attributed to the mutations in the SODIUM-GLUCOSE TRANSPORTER 2 encoded by the SLC5A2 gene.
Hypertension, Renal definition: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
renal hypertension definition: hypertension due to renal disease.
Kidney definition: Body organ that filters blood for the secretion of URINE and that regulates ion concentrations.
kidney definition: body organ that filters blood for the secretion of urine and that regulates ion concentrations.
kidneys definition: (KID-neez) A pair of organs in the abdomen that remove waste from the blood (as urine), produce erythropoietin (a substance that stimulates red blood cell production), and play a role in blood pressure regulation.
KIDNEY definition: One of the two bean-shaped organs located on each side of the spine in the retroperitoneum. The right kidney is located below the liver and the left kidney below the diaphragm. The kidneys filter and secret the metabolic products and minerals from the blood, thus maintaining the homeostasis. On the superior pole of each kidney there is an adrenal gland. Each kidney and adrenal gland is surrounded by fat. (NCI)
Kidney definition: One of the two bean-shaped organs located on each side of the spine in the retroperitoneum. The right kidney is located below the liver and the left kidney below the diaphragm. The kidneys filter and secret the metabolic products and minerals from the blood, thus maintaining the homeostasis. On the superior pole of each kidney there is an adrenal gland. Each kidney and adrenal gland is surrounded by fat.
Renal definition: Of or pertaining to the kidney.
Kidney Calculi definition: Stones in the KIDNEY, usually formed in the urine-collecting area of the kidney (KIDNEY PELVIS). Their sizes vary and most contains CALCIUM OXALATE.
Kidney Diseases definition: Pathological processes of the KIDNEY or its component tissues.
kidney disorder definition: impairment of health or a condition of abnormal functioning of the kidney.
Renal Disorder definition: A neoplastic or non-neoplastic condition affecting the kidney. Representative examples of non-neoplastic conditions include glomerulonephritis and nephrotic syndrome. Representative examples of neoplastic conditions include benign processes (e.g., renal lipoma and renal fibroma) and malignant processes (e.g., renal cell carcinoma and renal lymphoma).
Kidney Failure, Acute definition: A severe stage of acute renal insufficiency, characterized by the sudden decrease in GLOMERULAR FILTRATION RATE to less than 15 ml per min, sometime to less than 1 to 2 ml per min. It is usually associated with OLIGURIA; EDEMA; and increase in BLOOD UREA NITROGEN and serum CREATININE concentrations.
acute renal failure definition: clinical syndrome characterized by a sudden decrease in glomerular filtration rate, usually associated with oliguria and always associated with biochemical consequences of the reduction in glomerular filtration rate such as a rise in blood urea nitrogen (BUN) and serum creatinine concentrations.
Acute Renal Failure definition: Sudden and sustained deterioration of the kidney function characterized by decreased glomerular filtration rate, increased serum creatinine or oliguria.
Kidney Neoplasms definition: Tumors or cancers of the KIDNEY.
kidney neoplasm definition: new abnormal tissue of the kidney that grows by excessive cellular division and proliferation more rapidly than normal and continues to grow after the stimuli that initiated the new growth cease.
Renal Neoplasm definition: A benign or malignant neoplasm affecting the kidney. Representative examples of benign renal neoplasms include fibroma, lipoma, oncocytoma, and juxtaglomerular cell tumor. Representative examples of malignant renal neoplasms include renal cell carcinoma, renal pelvis carcinoma, Wilms tumor, rhabdoid tumor, sarcoma, and lymphoma.
Kidney Papillary Necrosis definition: A complication of kidney diseases characterized by cell death involving KIDNEY PAPILLA in the KIDNEY MEDULLA. Damages to this area may hinder the kidney to concentrate urine resulting in POLYURIA. Sloughed off necrotic tissue may block KIDNEY PELVIS or URETER. Necrosis of multiple renal papillae can lead to KIDNEY FAILURE.
cystic kidney definition: kidney containing one or more cysts, including polycystic disease, solitary cyst, multiple simple cysts, and retention cysts.
Renal Cyst definition: Abnormal fluid filled sac within the kidney, either acquired or congenital.
Kidney, Cystic definition: A kidney containing one or more cysts.
Nephrocalcinosis definition: A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.
nephrocalcinosis definition: condition characterized by precipitation of calcium phosphate in the tubules of the kidney, with resultant renal insufficiency.
Nephrosclerosis definition: Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA.
nephrosclerosis definition: sclerosis or hardening of the kidney due to renovascular disease.
Renal Agents definition: Drugs used for their effects on the kidneys' regulation of body fluid composition and volume. The most commonly used are the diuretics. Also included are drugs used for their antidiuretic and uricosuric actions, for their effects on the kidneys' clearance of other drugs, and for diagnosis of renal function.
Renal Artery definition: A branch of the abdominal aorta which supplies the kidneys, adrenal glands and ureters.
renal artery definition: branch of the abdominal or ventral aorta which supplies the kidneys, adrenal glands and ureters in vertebrates.
Renal Circulation definition: The circulation of the BLOOD through the vessels of the KIDNEY.
kidney circulation definition: vessels, supply, and flow of blood through the vascular system of the kidney.
Kidney Failure definition: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal failure, either acute (KIDNEY FAILURE, ACUTE) or chronic (KIDNEY FAILURE, CHRONIC), requires HEMODIALYSIS.
renal failure definition: inability of a kidney to excrete metabolites at normal plasma levels under conditions of normal loading or inability to retain electrolytes under conditions of normal intake.
Renal Failure definition: Acute or chronic condition, characterized by the inability of the kidneys to adequately filter the blood substances, resulting in uremia and electrolyte imbalances. Acute renal failure is usually associated with oliguria or anuria, hyperkalemia, and pulmonary edema. Chronic renal failure is irreversible and requires hemodialysis.--2004
Renal Osteodystrophy definition: Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.
Renal Colic definition: Paroxysmal and severe flank pain radiating to the inguinal area. It is caused by the passage of a kidney stone through the ureter.
Renal Colic definition: A severe pain in the lower back radiating to the groin, scrotum, and labia which is most commonly caused by a kidney stone (RENAL CALCULUS) passing through the URETER or by other urinary track blockage. It is often associated with nausea, vomiting, fever, restlessness, dull pain, frequent urination, and HEMATURIA.
Renal Alteration definition: Change in or modification of the kidney function.
Kidney Pelvis definition: The flattened, funnel-shaped expansion connecting the URETER to the KIDNEY CALICES.
renal pelvis definition: The area at the center of the kidney. Urine collects here and is funneled into the ureter, the tube that connects the kidney to the bladder.
Renal Pelvis definition: The funnel-shaped proximal portion of the ureter located within the kidney into which urine is secreted, from the collecting duct system of the kidney.
Renal Angiomyolipoma definition: An angiomyolipoma arising from the kidney.
Renal Adenoma definition: An adenoma arising from the renal cortex.
Malignant Renal Neoplasm definition: Primary or metastatic malignant neoplasm involving the kidney. --2003
Renal Dialysis definition: Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION.
Renal Carcinoma definition: A carcinoma arising from the epithelium of the renal parenchyma (renal cell carcinoma) or the renal pelvis (renal pelvis carcinoma). The vast majority of renal cell carcinomas are adenocarcinomas. The vast majority of renal pelvis carcinomas are transitional cell carcinomas. Renal carcinomas usually affect middle aged and elderly adults. Hematuria, abdominal pain, and a palpable mass are common symptoms. -- 2004
Renal Insufficiency definition: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE. The most severe form is KIDNEY FAILURE. Renal function may deteriorate slowly (RENAL INSUFFICIENCY, CHRONIC) or precipitously (RENAL INSUFFICIENCY, ACUTE).
renal absorption definition: A renal system process by which water, ions, and glucose are taken up from the collecting ducts and proximal and distal loops of the nephron. [GOC:dph, GOC:mah]
Nierenstein definition: [1] steinartige Ablagerungen in der Niere, die aus Bestandteilen des Harns bestehen
renal definition: [1] Anatomie: die Nieren betreffend, zur Niere gehörig