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Subtype definition: A group forming a type within a larger type.
Mucin-5B definition: A gel-forming mucin that is predominantly expressed by submucosal glands of airway tissues and the SUBLINGUAL GLAND. It is one of the principal components of high molecular weight salivary mucin.
Bombesin-like Receptor 3 definition: Expressed in germ cells in the testis by human BRS3 Gene (GPCR1 Family), 399-aa 44-kDa integral membrane protein Bombesin-like Receptor 3 is specifically activated by bombesin-like peptides and associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. Bombesin-like peptide receptors include gastrin-releasing peptide receptor, neuromedin B receptor, and bombesin receptor subtype-3 (BRS3). BRS3 may be required for sperm cell division, maturation, or function, or for regulation of endocrine processes and metabolism responsible for energy balance and adiposity. (NCI)
ADRA2A Gene definition: This gene plays a role in the regulation of neurotransmitter release from nerves and neurons in the central nervous system.
BRS3 Gene definition: This gene is involved in the regulation of metabolic and endocrine processes required for energy storage and consumption.
Adenosine Receptor A2a definition: Expressed in basal ganglia, vasculature, and platelets by human ADORA2A Gene (GPCR1 Family), 412-aa 45-kDa Adenosine A2A Receptor is a cell-surface integral membrane protein containing 7 transmembrane domains that interacts with a heterotrimeric G protein complex in response to adenosine ligand to stimulate cAMP accumulation through adenylate cyclase activation, is a major target of caffeine, and modulates the activity of various neuronal populations, platelets, neutrophils, and mast cells, and smooth muscle cells in bronchi and vasculature. A potent biologic mediator, most effects of adenosine protect cells during stress.
Adenosine Receptor A2a definition: Adenosine receptor A2a (412 aa, 45 kD) is a cell defense response protein that is encoded by the human ADORA2A gene and has roles in G protein-coupled cell-cell signaling, cellular defense response, phagocytosis, blood circulation, inflammatory response, sensory perception and central nervous system development.
has subtype definition: Target concept is a subtype / subclass or the source (or the target concept implies the source
Subtype constraint definition: This row corresponds to a subcomponent of the row above; it would not normally be included in an Refined Message Information Model, but it is included in order to be able to state a constraint on the subtype. This is explained in 10.2.2.4.
Subtype constraint definition: This row corresponds to a subcomponent of the row above; it would not normally be included in an HMD, but it is included in order to be able to state a constraint on the subtype. This is explained in 10.2.2.4.
Influenza A Virus, H9N2 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 9 and neuraminidase 2. The H9N2 subtype usually infects domestic birds (POULTRY) but there have been some human infections reported.
Influenza A Virus, H7N7 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 7 and neuraminidase 7. The H7N7 subtype produced an epidemic in 2003 which was highly pathogenic among domestic birds (POULTRY). Some infections in humans were reported.
Influenza A Virus, H5N2 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 5 and neuraminidase 2. The H5N2 subtype has been found to be highly pathogenic in chickens.
Influenza A Virus, H5N1 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 5 and neuraminidase 1. The H5N1 subtype, frequently referred to as the bird flu virus, is endemic in wild birds and very contagious among both domestic (POULTRY) and wild birds. It does not usually infect humans, but some cases have been reported.
Influenza A Virus, H3N8 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 3 and neuraminidase 8. The H3N8 subtype has frequently been found in horses.
Influenza A Virus, H3N2 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 3 and neuraminidase 2. The H3N2 subtype was responsible for the Hong Kong flu pandemic of 1968.
Influenza A Virus, H1N1 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 1 and neuraminidase 1. The H1N1 subtype was responsible for the Spanish flu pandemic of 1918.
Influenza A Virus, H2N2 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 2 and neuraminidase 2. The H2N2 subtype was responsible for the Asian flu pandemic of 1957.
Lung Adenocarcinoma, Mixed Subtype definition: The most frequently seen morphologic variant of lung adenocarcinoma characterized by a mixture of architectural patterns, including acinar, papillary, bronchioloalveolar, and solid pattern. (NCI05)
TOAST Classification definition: A classification of subtypes of ischemic stroke based on clinical features and the results of ancillary diagnostic studies.The TOAST classification denotes five subtypes of ischemic stroke: 1) large-artery atherosclerosis, 2) cardioembolism, 3) small-vessel occlusion, 4) stroke of other determined etiology, and 5) stroke of undetermined etiology.
Regulatory Application Document Subtype definition: A subset category identified within a larger group of regulatory application documents. A document subtype provides more specific context for the documentation. It contains name value pairs and keywords that are used within the context of the application.
Document Subtype definition: A subset category identified within a larger group of documents. A document subtype provides more specific context for the documentation.
Influenza A Virus, H1N2 Subtype definition: A subtype of INFLUENZA A VIRUS comprised of the surface proteins hemagglutinin 1 and neuraminidase 2. It is endemic in both human and pig populations.