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Definition
 
enEnglish
transcription, RNA-dependent definition: The synthesis of DNA on a template of RNA. [GOC:jl]
Reverse Transcription definition: The biosynthesis of DNA carried out on a template of RNA.
Reverse Transcription definition: The action of copying RNA into DNA by reverse transcriptase.
Transcription Factors definition: Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process.
transcription factor definition: diverse group of viral, prokaryotic, and eukaryotic proteins which interact with specific sites on DNA or its associated proteins to initiate or inhibit transcription; not all are DNA binding proteins per se, although that is a BT.
Transcription Factor definition: Transcription factors are a diverse group of proteins that bind to DNA at specific promoter or enhancer regions. They also bind to DNA-associated proteins to initiate, stimulate, inhibit or terminate transcription. The proteins are often physically associated in a preinitiation complex and contain structural motifs.
Transcription, Genetic definition: The biosynthesis of RNA carried out on a template of DNA. The biosynthesis of DNA from an RNA template is called REVERSE TRANSCRIPTION.
genetic transcription definition: transfer of genetic information from DNA to messenger RNA by DNA-directed RNA polymerase; includes reverse transcription and transcription of early and late genes expressed early in an organism's life cycle or during later development.
transcription definition: The synthesis of either RNA on a template of DNA or DNA on a template of RNA. [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
Transcription definition: A genetic process in which single-stranded RNA with base sequence complementary to a region of plus strand DNA is synthesized by DNA-dependent RNA polymerases. Following the binding of RNA polymerase on the DNA promoter regions, the RNA product is synthesized in a 5' to 3' direction, elongating the DNA strand as the polymerase proceeds down the unwinding and rewinding of the DNA helix.
Enhancer definition: A 50-150bp DNA sequence that increases the rate of transcription of coding sequences. It may be located at various distances and in either orientation upstream from, downstream from or within a structural gene. When bound by a specific transcription factor it increases the levels of expression of the gene, but is not sufficient alone to cause expression. Distinguished from a promoter, that is alone sufficient to cause expression of the gene when bound.
Activating Transcription Factor 4 definition: An activating transcription factor that regulates the expression of a variety of GENES involved in amino acid metabolism and transport. It also interacts with HTLV-I transactivator protein.
Transcriptional Activation definition: Processes that stimulate the GENETIC TRANSCRIPTION of a gene or set of genes.
Transcriptional Activation definition: The process by which an unexpressed gene is activated to serve as a transcription template for synthesis of RNA.
CCAAT-Enhancer-Binding Protein-beta definition: A CCAAT-enhancer-binding protein found in LIVER; INTESTINES; LUNG and ADIPOSE TISSUE. It is an important mediator of INTERLEUKIN-6 signaling.
Activating Transcription Factor 1 definition: An activating transcription factor that regulates expression of a variety of genes including C-JUN GENES and TRANSFORMING GROWTH FACTOR BETA2.
Activating Transcription Factor 3 definition: An activating transcription factor that plays a key role in cellular responses to GENOTOXIC STRESS and OXIDATIVE STRESS.
Sterol Regulatory Element Binding Protein 1c definition: SREBP1-C is an isoform of sterol regulatory element binding protein 1 that is a weak activator of GENETIC TRANSCRIPTION. It is the predominant form in LIVER and ADIPOCYTES, and it mediates INSULIN induced FATTY ACIDS synthesis.
Core Binding Factor Alpha 1 Subunit definition: A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION.
transcription termination definition: The process by which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA. [ISBN:0716720094]
Transcription Termination definition: Transcription Termination is the cessation of cellular activities involved in the synthesis a nascent RNA transcript.
Transcriptional Repression definition: Decreased expression of some gene product.
Activating Transcription Factor 2 definition: ATF proteins have been reported to be able to bind with FOS proteins to form the AP-1 transcription factor (from Nature Cell Biol. 4: E131-E136, 2002 via OMIM)
Activating Transcription Factor 2 definition: The CRE octanucleotide mediates inducible transcription of genes that respond to cAMP levels. Some growth control genes have CRE transcriptional regulatory regions. Containing a leucine zipper linked to a basic DNA-binding domain, transcription factor ATF2 is a CRE-binding protein that forms a homodimer or a heterodimer with c-JUN. ATF2 also appears to be a histone acetyltransferase specific for H2B and H4. Motif A, in the HAT domain, is responsible for CRE-dependent stimulation of transcription. (from OMIM 123811 and NCI)
Activating Transcription Factors definition: Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact with early promoters from ADENOVIRUSES. They are a family of basic leucine zipper transcription factors that bind to the consensus site TGACGTCA of the cyclic AMP response element, and are closely related to CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN.
positive regulation of transcription, mitotic definition: Any process that activates or increases the frequency, rate or extent of transcription during mitosis. [GOC:go_curators]
regulation of transcription definition: Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA. [ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
Transcriptional Regulation definition: The control of gene expression at the level of RNA transcription.
antisense RNA transcription definition: The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA. [GOC:jl, http://cancerweb.ncl.ac.uk/]
snoRNA transcription definition: The synthesis of small nucleolar RNA (snoRNA) from a DNA template. [GOC:jl]
rRNA transcription definition: The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template. [GOC:jl, ISBN:0198506732 "Oxford Dictionary of Biochemistry and Molecular Biology"]
mRNA transcription definition: The synthesis of messenger RNA (mRNA) from a DNA template. [GOC:jl]
viral transcription definition: The mechanisms involved in viral gene transcription, especially referring to those with temporal properties unique to viral transcription. [ISBN:0781702534]
snRNA transcription definition: The synthesis of small nuclear RNA (snRNA) from a DNA template. [GOC:jl, ISBN:0321000382]
tRNA transcription definition: The synthesis of transfer RNA (tRNA) from a DNA template. [GOC:jl]
transcription initiation definition: Any process involved in the assembly of the RNA polymerase complex at the promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. [GOC:jic]
Transcription Initiation definition: Transcription Initiation involves RNA polymerase (and usually other factors) binding at a specific gene promoter DNA site followed by local DNA unwinding and inauguration of the 5-prime to 3-prime biosynthesis of an RNA transcript complementary to the DNA template.
Ada2/Gcn5/Ada3 transcription activator complex definition: A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. [PMID:10637607]
5S class rRNA transcription definition: The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template. [GOC:jl, ISBN:0321000382]
ATF2 Gene definition: This gene plays a role in transcriptional regulation and histone acetylation.
Transcription Coactivator definition: A transcription cofactor that activates transcription from a RNA polymerase II promoter but does not bind DNA itself.
Transcription Repressor/Corepressor definition: Transcription Repressor/Corepressor Gene encodes Transcriptional Repressor/Corepressor, proteins that can regulate transcription by binding to the operator and causing repression. (from Glick: Glossary of Biochemistry and Molecular Biology)
cAMP Responsive Element Binding Protein 1 definition: Encoded as alternative A, B isoforms by human CREB1 Gene (bZIP/CREB Family), nuclear cAMP Responsive Element Binding Protein 1 is a homodimeric transcription factor containing 1 KID domain, phosphorylated/stimulated by several protein kinases, that binds to octameric DNA palindrome cAMP-response elements (CRE) present in many viral and cellular promoters and induces gene transcription in response to hormonal stimulation of the cAMP pathway. (NCI)
Transcription Alteration definition: Transcription Alteration involves a change in the quality of the existing state of the cellular process in which genetic information is transferred from DNA to messenger RNA by DNA-directed RNA polymerase.
Transcription Elongation definition: The RNA polymerase moves along the DNA template, adding nucleotides to the growing RNA chain in accordance with the sequence of the template or coding strand.
Transcription Process definition: A Transcription Process is any cellular event or activity directly involved in the synthesis a nascent RNA transcript.
positive regulation of transcription factor activity definition: Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription. [GOC:ai]
Activating Transcription Factor 6 definition: One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response.
Activating Transcription Factor 2 definition: An activating transcription factor that regulates expression of a variety of GENES including C-JUN GENES; CYCLIN A; CYCLIN D1; and ACTIVATING TRANSCRIPTION FACTOR 3.
transcription antitermination definition: Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond a termination site. [ISBN:0198577788, PMID:12456320]
positive regulation of CREB transcription factor activity definition: Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB. [GOC:dph, GOC:ecd, GOC:tb]
negative regulation of transcription by transcription factor catabolism definition: Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a transcription factor. [GOC:dph, GOC:tb]
negative regulation of transcription by transcription factor localization definition: Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor. [GOC:dph, GOC:tb]
transcription definition: Transcription.
 
 
deGerman
Transkription definition: [1] Linguistik: Wiedergabe der Aussprache sprachlicher Einheiten mit phonetischen oder phonologischen Schriftzeichen; der Begriff wird oft nur im Sinne von phonetische Transkription aufgefasst [2] Wiedergabe eines Textes, der in einer anderen Schrift verfasst ist, in lateinischer Schrift, oder umgekehrt
phonetische Transkription definition: [1] Linguistik: Wiedergabe sprachlicher Äußerungen in Lautschrift
phonetische Umschrift definition: [1] Linguistik: Wiedergabe sprachlicher Äußerungen in Lautschrift
 
frFrench
facsimilé definition: Reproduction exacte, imprimée, gravée, ou photographiée, d’une peinture, d’une signature, d’un dessin, d'un ouvrage unique, rare, ou épuisé, etc.
facsimilé definition: Document numérisé, transmis par liaison téléphonique, puis imprimé par le matériel de réception. Il est plus couramment connu sous l'acronyme ''fax''
facsimilé definition: L'appareil permettant la numérisation, la transmission, la réception, et l'impression du '''facsimilé''' (appelé aussi ''télécopieur'' ou ''téléfax'').
transcription definition: Action de transcrire ou résultat de cette action.
transcription definition: Opération consistant à substituer à chaque graphème d’un système d’écriture un graphème ou un groupe de graphèmes d’un autre, afin de rendre la prononciation.
transcription definition: Action de noter de la musique pour un instrument autre que celui pour lequel elle a été écrite, et du résultat de cette action.
transcription definition: Synthèse d'une molécule d'acide ribonucléique à partir d'une matrice d'acide désoxyribonucléique.
fac-similé definition: Reproduction exacte, imprimée, gravée, ou photographiée, d’une peinture, d’une signature, d’un dessin, d'un ouvrage unique, rare, ou épuisé, etc.
fac-similé definition: Document numérisé, transmis par liaison téléphonique, puis imprimé par le matériel de réception. Il est plus couramment connu sous l'acronyme ''fax''
fac-similé definition: L'appareil permettant la numérisation, la transmission, la réception, et l'impression du '''fac-similé''' (appelé aussi ''télécopieur'' ou ''téléfax'').
retranscription definition: Transcription de nouveau, action de recopier un texte.
retranscription definition: Adaptation d’un récit sous forme écrite.