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The Barcelona Declaration, issued by the Surviving Sepsis Campaign in October 2002, outlines a six-point plan to reduce the relative mortality of sepsis by 25% over the next 5 years.

Elizabeth Slade et al.

Critical Care 7 (1), 2003

But, unlike tobacco control policy, there is little evidence about what public policies would work to substantially reduce childhood obesity.

Stephen D Sugarman et al.

Australia and New Zealand Health Policy 5 (7), 18 Nov 2008

In turn, countries are looking primarily to the business sector to implement the most efficient mechanisms to reduce society's overall carbon footprint.

Stephen D Sugarman et al.

Australia and New Zealand Health Policy 5 (7), 18 Nov 2008

First, there are no evidence-based policy interventions for them to support that are reliably going to reduce childhood obesity rates in a significant way.

Stephen D Sugarman et al.

Australia and New Zealand Health Policy 5 (7), 18 Nov 2008

Yet, one of the beauties of performance-based regulation is that the food industry would not be asked to eliminate the problem, but instead only significantly to reduce it.

Stephen D Sugarman et al.

Australia and New Zealand Health Policy 5 (7), 18 Nov 2008

This is in contrast to the possible use of performance-based regulation, say, to reduce highway fatality rates.

Stephen D Sugarman et al.

Australia and New Zealand Health Policy 5 (7), 18 Nov 2008

There, if Toyota were told, for example, to reduce by 25% the number of people killed on the roads while in Toyota-made vehicles, the relevant agency could readily measure whether or not Toyota had achieved its regulatory target.

Stephen D Sugarman et al.

Australia and New Zealand Health Policy 5 (7), 18 Nov 2008

These costs continue to escalate as continued applications of existing technology are unlikely to markedly reduce disparities.

Rebecca L Slayton et al.

BMC Oral Health 6 (Suppl 1), 15 Jun 2006

The purpose of this conference was to develop a research agenda that will leverage new discoveries and lead to innovative approaches to reduce caries in high risk populations.

Rebecca L Slayton et al.

BMC Oral Health 6 (Suppl 1), 15 Jun 2006

Future Goals One of the stated goals of this conference was to develop a research agenda that, if adopted by investigators and funders, will leverage recent discoveries and lead to innovative new approaches to reduce caries in high-risk populations.

Rebecca L Slayton et al.

BMC Oral Health 6 (Suppl 1), 15 Jun 2006

Strategies identified in the breakout sessions were then organized into specific topics that could inform a future request for applications from government, foundations, or industry in the area of biotechnology and bioengineering approaches to reduce disparities in dental caries.

Rebecca L Slayton et al.

BMC Oral Health 6 (Suppl 1), 15 Jun 2006

Development of New Technologies or Delivery Systems • Modification of xylitol delivery systems to reduce the number of doses while maintaining its effect.

Rebecca L Slayton et al.

BMC Oral Health 6 (Suppl 1), 15 Jun 2006

Our method, c-REDUCE, can account for variability at a motif position inferred from evolutionary information. c-REDUCE has been tested on ChIP-chip data for yeast transcription factors and on gene expression data in Drosophila .

Katerina Kechris et al.

BMC Bioinformatics 9 (7), 28 Nov 2008

The correlation-based motif finding approach was introduced in the "Regulatory Element Detection Using Correlation with Expression" (REDUCE) software [ 4 ] using a linear regression framework and has since been adapted in several ways including the use of scores to motifs instead of oligo counts [ 6 ], probabilistic representations of motifs [ 7 ], binary indicators for word occurrences [ 8 ] and flexible non-linear regression functions [ 9 , 10 ].

Katerina Kechris et al.

BMC Bioinformatics 9 (7), 28 Nov 2008

To search for degenerate motifs, we have developed an adaptation of the correlation-based algorithm REDUCE [ 4 ] called conservation-REDUCE (c-REDUCE).

Katerina Kechris et al.

BMC Bioinformatics 9 (7), 28 Nov 2008

In c-REDUCE, a multiple species alignment is generated and then translated into a consensus pattern using degenerate nucleotide symbols that capture the variation at each position across species.

Katerina Kechris et al.

BMC Bioinformatics 9 (7), 28 Nov 2008

By using multiple species data, we can identify motifs that may be missed by REDUCE, which only examines sequences from a single species and requires exactly the same oligo in different sequences.

Katerina Kechris et al.

BMC Bioinformatics 9 (7), 28 Nov 2008

2007 Alternative ways to control caterpillar pests and reduce the use of pesticides in apple orchards are in the interest of the environment, farmers and the public.

Christel M.M. Mols et al.

PLoS ONE 2 (2), 07 Feb 2007

Great tits have already been shown to reduce damage under high caterpillar density when breeding in nest boxes in an experimental apple orchard.

Christel M.M. Mols et al.

PLoS ONE 2 (2), 07 Feb 2007

In this study we investigated whether great tits can reduce caterpillar damage in commercially managed apple orchards, with either Integrated Pest Management (IPM) or Organic Farming (OF), by measuring damage levels of the apples in areas with and without breeding great tits.

Christel M.M. Mols et al.

PLoS ONE 2 (2), 07 Feb 2007

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