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Chloroprene definition: Toxic, possibly carcinogenic, monomer of neoprene, a synthetic rubber; causes damage to skin, lungs, CNS, kidneys, liver, blood cells and fetuses. Synonym: 2-chlorobutadiene.
Chloroprene definition: A colorless, flammable, carcinogenic, chlorinated hydrocarbon with a pungent, ethereal odor. Chloroprene is used as a chemical intermediate in the manufacture of neoprene rubber. Exposure to this substance causes damage to the skin, lungs, CNS, kidneys, liver and depression of the immune system. Chloroprene is a mutagen and carcinogen in animals and is reasonably anticipated to be a human carcinogen. (NCI05)
Neoprene definition: An oil-resistant synthetic rubber made by the polymerization of chloroprene.
1,3-Butadiene definition: A synthetic, colorless gas that is practically insoluble in water and soluble in ethanol, ether, acetone and benzene. It is used primarily as a monomer to manufacture many different types of polymers and copolymers and as a chemical intermediate in the production of industrial chemicals. When heated, 1,3-butadiene emits acrid fumes and is flammable. In the presence of air, it oxidizes to form explosive peroxides. The primary route of potential human exposure to this compound is inhalation. Acute exposure to 1,3-butadiene can cause irritation of the eyes, nasal passages and throat. At very high concentrations, inhalation of this gas can result in headache, fatigue, decreased blood pressure and pulse rate, central nervous system damage and unconsciousness. It is known to be a human carcinogen. (NCI05)
 
Publications
 

Carcinogenicity of 1,3-butadiene.

R L Melnick et al.

Environmental Health Perspectives , 01 Apr 1993

The industrial production and use of 1,3-butadiene.

N L Morrow

Environmental Health Perspectives , 01 Jun 1990

Occupational exposure of workers to 1,3-butadiene.

J M Fajen et al.

Environmental Health Perspectives , 01 Jun 1990

Cancer risk assessment of 1,3-butadiene.

I L Cote et al.

Environmental Health Perspectives , 01 Jun 1990

In vitro and in vivo genotoxicity of 1,3-butadiene and metabolites.

G T Arce et al.

Environmental Health Perspectives , 01 Jun 1990

Assessment of 1,3-butadiene epidemiology studies.

M G Ott

Environmental Health Perspectives , 01 Jun 1990

Industrial emissions of 1,3-butadiene.

J A Mullins

Environmental Health Perspectives , 01 Jun 1990

Species differences in the metabolism and disposition of inhaled 1,3-butadiene and isoprene.

A R Dahl et al.

Environmental Health Perspectives , 01 Jun 1990

Inhalation pharmacokinetics of 1,3-butadiene and 1,2-epoxybutene-3 in rats and mice.

R J Laib et al.

Environmental Health Perspectives , 01 Jun 1990

Assessment of the potential risk to workers from exposure to 1,3-butadiene.

D Turnbull et al.

Environmental Health Perspectives , 01 Jun 1990

45 further publications >>