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arachidonate 8-lipoxygenase activity definition: Catalysis of the reaction: arachidonate + O2 = (5Z,9E,11Z,14Z)-(8R)-8-hydroperoxyicosa-5,9,11,14-tetraenoate. [EC:1.13.11.40, MetaCyc:ARACHIDONATE-8-LIPOXYGENASE-RXN]