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Antigens, CD86 definition: A CD antigen that plays a role in T-lymphocyte proliferation and interleukin 2 production. It is a co-stimulatory ligand for the CD28 ANTIGEN on T-LYMPHOCYTES and initiates T-cell activation and immune response.
CD86 wt Allele definition: Human CD86 wild-type allele is located in the vicinity of 3q21 and is approximately 66 kb in length. This allele, which encodes T-lymphocyte activation antigen CD86 protein, is involved in the regulation of both interleukin production and T-cell proliferation.
T-Lymphocyte Activation Antigen CD86 definition: T-lymphocyte activation antigen CD86 (329 aa, ~38 kDa) is encoded by the human CD86 gene. This protein plays a role in signal transduction that mediates T-cell proliferation and interleukin gene transcription.
 
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