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Definition
 
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Cholinesterase Inhibitors definition: Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
cholinesterase inhibitor definition: any substance or agent which suppresses, prevents or opposes the action of cholinesterase resulting in the potentiation of the action of endogenously released acetylcholine at cholinergic synapses; cholinesterase inhibition is associated with a variety of acute symptoms such as nausea, vomiting, blurred vision, stomach cramps, and rapid heart rate.
cholinesterase definition: enzyme of the hydrolase class that catalyzes the cleavage of the acyl group from various esters of choline, including acetylcholine, and some related compounds the enzyme occurs primarily in the serum, liver, and pancreas determination of enzyme activity is used to test liver function, succinylcholine sensitivity, and whether organophosphate insecticide poisoning has occurred.
 
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