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Thiamine Pyrophosphate definition: The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
thiamine pyrophosphate definition: biologically active form of thiamin and a cofactor for many oxidative decarboxylation reactions in carbohydrate metabolism.
thiamin pyrophosphate binding definition: Interacting selectively with thiamin pyrophosphate, the diphosphoric ester of thiamin. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases. [GOC:mlg, http://cancerweb.ncl.ac.uk/]
 
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