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Deuterium definition: Deuterium. The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.
deuterium definition: stable isotope of hydrogen; has one neutron and one proton in the nucleus.
H-2 Antigens definition: The major group of transplantation antigens in the mouse.
Histamine H2 Antagonists definition: Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
Hydrogenase definition: An enzyme found in bacteria. It catalyzes the reduction of FERREDOXIN and other substances in the presence of molecular hydrogen and is involved in the electron transport of bacterial photosynthesis.
hydrogenase definition: specific enzyme (EC 1.18.99.1) that catalyzes the conversion of H+ to hydrogen gas via oxidation of ferredoxin; do not use for general term to cover other hydrogenating enzymes.
Receptors, Histamine H2 definition: A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate adenylate cyclase. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5)
Antigens, CD30 definition: A member of the tumor necrosis factor receptor superfamily that may play a role in the regulation of NF-KAPPA B and APOPTOSIS. They are found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; NEUTROPHILS; EOSINOPHILS; MAST CELLS and NK CELLS. Overexpression of CD30 antigen in hematopoietic malignancies make the antigen clinically useful as a biological tumor marker. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
TNF Receptor 8 definition: Expressed in activated T- and B-cells by human TNFRSF8 Gene (TNFR Superfamily) as distinct serine and tyrosine phosphorylated Long (595-aa, 64-kDa precursor type I membrane protein) and Short (cytoplasmic) isoforms, TNF Receptor 8 contains 6 TNFR-Cys repeats. A positive regulator of apoptosis and receptor for TNFSF8/CD30L, TNFRSF8 interacts with the TRAF1, TRAF2, TRAF3, and TRAF5 mediators of signal transduction and regulates gene expression through NF-Kappa-B activation. A Hodgkin's disease associated antigen, TNFRSF8 limits the proliferative potential of autoreactive CD8 effector T cells and protects against autoimmunity. (NCI)
Prostaglandin H2 definition: A cyclic endoperoxide intermediate produced by the action of CYCLOOXYGENASE on ARACHIDONIC ACID. It is further converted by a series of specific enzymes to the series 2 prostaglandins.
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