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connective tissue growth factor production definition: The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. [GOC:mah]
regulation of connective tissue growth factor production definition: Any process that modulates the frequency, rate, or extent of connective tissue growth factor production. [GOC:mah]
negative regulation of connective tissue growth factor production definition: Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production. [GOC:mah]
positive regulation of connective tissue growth factor production definition: Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production. [GOC:mah]
CTGF wt Allele definition: Human CTGF wild-type allele is located in the vicinity of 6q23.1 and is approximately 3 kb in length. This allele, which encodes connective tissue growth factor protein, is involved in mitogen stimulation and cellular growth signal transduction through the TGFbeta/Smad signaling pathway. The stimulation appears to be regulated by growth factors or specific oncogenes.
 
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