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Major Histocompatibility Complex definition: The genetic region which contains the loci of genes which determine the structure of the serologically defined (SD) and lymphocyte-defined (LD) TRANSPLANTATION ANTIGENS, genes which control the structure of the IMMUNE RESPONSE-ASSOCIATED ANTIGENS, HUMAN; the IMMUNE RESPONSE GENES which control the ability of an animal to respond immunologically to antigenic stimuli, and genes which determine the structure and/or level of the first four components of complement.
major histocompatibility complex definition: genetic region found in all mammals whose products are primarily reponsible for the rapid rejection of grafts between individuals and which signal between lymphocytes and cells expressing antigen; H-2 in mouse and HLA in humans.
 
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Disruption and pseudoautosomal localization of the major histocompatibility complex in monotremes

Juliane C Dohm et al.

Genome Biology , 2007

The major histocompatibility complex (MHC) Ea promoter: sequences and factors at the initiation site.

R Mantovani et al.

Nucleic Acids Research , 25 Oct 1993

A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish

Jennifer G Sambrook et al.

BMC Genomics , 04 Nov 2005

IMGT/HLA Database—a sequence database for the human major histocompatibility complex

James Robinson et al.

Nucleic Acids Research , 01 Jan 2001

Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex

Katherine Belov et al.

PLoS Biology , 01 Mar 2006

Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice

Ann-Sofie Hansson et al.

Arthritis Research & Therapy , 2004

Sequences, Annotation and Single Nucleotide Polymorphism of the Major Histocompatibility Complex in the Domestic Cat

Naoya Yuhki et al.

PLoS ONE , 16 Jul 2008

Regulation of major histocompatibility complex class II gene expression in trophoblast cells

Shawn P Murphy et al.

Reproductive biology and endocrinology : RB&E , 05 Jul 2004

DNA Methylation Profiling of the Human Major Histocompatibility Complex: A Pilot Study for the Human Epigenome Project

Vardhman K Rakyan et al.

PLoS Biology , 01 Dec 2004

Generation of a genomic tiling array of the human Major Histocompatibility Complex (MHC) and its application for DNA methylation analysis

Eleni M Tomazou et al.

BMC Medical Genomics , 30 May 2008

209 further publications >>