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Islets of Langerhans definition: Irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the PANCREAS among the exocrine acini. Each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. There are four major cell types. The most abundant beta cells (50-80%) secrete INSULIN. Alpha cells (5-20%) secrete GLUCAGON. PP cells (10-35%) secrete PANCREATIC POLYPEPTIDE. Delta cells (~5%) secrete SOMATOSTATIN.
pancreatic islet definition: irregular microscopic structures, varying from a few to hundreds of cells, scattered throughout the pancreas and comprising its endocrine portion; cell types include: alpha, secreting glucagon; beta, secreting insulin; delta, secreting somatostatin; and PP, secreting pancreatic polypeptide.
islets of Langerhans definition: (EYE-lets of LANG-er-hanz) Cells in the pancreas that produce hormones (including insulin).
 
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