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ROBO4 wt Allele definition: Human ROBO4 wild-type allele is located in the vicinity of 11q24.2 and is approximately 14 kb in length. This allele, which encodes roundabout homolog 4 protein, is involved in the modulation of both angiogenesis and vascular patterning. Aberrant expression of the gene may be associated with tumor angiogenesis.
 
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