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The herbs that are traditionally used for anticancer treatment and that are anti-angiogenic through multiple interdependent processes (including effects on gene expression, signal processing, and enzyme activities) include Artemisia annua (Chinese wormwood), Viscum album (European mistletoe), Curcuma longa (curcumin), Scutellaria baicalensis (Chinese skullcap), resveratrol and proanthocyanidin (grape seed extract), Magnolia officinalis (Chinese magnolia tree), Camellia sinensis (green tea), Ginkgo biloba, quercetin, Poria cocos, Zingiber officinalis (ginger), Panax ginseng, Rabdosia rubescens hora (Rabdosia), and Chinese destagnation herbs.

S.M. Sagar et al.

Current Oncology 13 (1), 01 Feb 2006

4.1.6 Magnolia officinalis (Chinese Magnolia Tree) The seed cones of the Chinese magnolia tree contain substances that inhibit the growth of new blood vessels.

S.M. Sagar et al.

Current Oncology 13 (1), 01 Feb 2006

Table III Natural health products with potential direct and indirect anti-angiogenic activity a Herbs and associated phytochemicals   Aloe barbadensis (aloe vera leaf and pulp extracts)   Angelica sinensis (aqueous extracts)   Artemisia annua (artemisinin)   Camellia sinensis (epigallocatechin)   Chrysobalanus icaco (methanol extract)   Curcuma longa (curcumin)   Dysoxylum binectariferum (flavopiridol)  Flos magnoliae (magnosalin)   Ganoderma lucidum (triterpenoids)   Ginkgo biloba (ginkgolide B)   Glycyrrhiza glabra (isoliquiritigenin,; glabridin)   Hibiscus sabdariffa L. (protocatechuic acid)   Livistona chinensis (aqueous extract from seed)   Matricaria chamomilla (flavonoids: apigenin, fisetin)   Ocimum sanctum (carnosol, ursolic acid)  Omega-3 fatty acids (eicosapentaenoic acid, docosahexaenoic acid)   Magnolia obovata (honokiol)  Panax ginseng (saponins: 20(R)- and 20(S)-ginsenoside-Rg3)   Polypodium leucotomos (difur)   Poria cocos (1–3-α- d -glucan)   Polygonum cuspidatum (resveratrol)  Proanthocyanidin  Quercetin   Rabdosia rubescens Hora (ponicidin and oridonin)   Rosmarinus officinalis (carnosol and ursolic acid)   Scutellaria baicalensis (baicalin and baicalein)   Silybum marianum (silymarin)  Soy isoflavones (genistein, daidzein)   Tanacetum parthenium L. (parthenolide)   Tabebuia avellanedae (β-lapachone)   Taxus brevifolia (taxoids)   Viscum album (lectins)   Zingiber officinale (6-gingerol)  Other Chinese herbs (see Table VI )  Cyclo-oxygenase-2 antagonists (see Table IV ) Minerals  Selenium Animal-derived  Bovine cartilage  Shark cartilage (water soluble extract AE-941)  Squalus acanthias (dogfish liver: squalamine)  Vitamin D (1α ,25-D 3 ) a Data derived from in vitro and in vivo studies cited in text.

S.M. Sagar et al.

Current Oncology 13 (1), 01 Feb 2006

The herbs that are traditionally used for anti-cancer treatment and that are anti-angiogenic through multiple interdependent processes (including effects on gene expression, signal processing, and enzyme activities) include Artemisia annua (Chinese wormwood), Viscum album (European mistletoe), Curcuma longa (curcumin), Scutellaria baicalensis (Chinese skullcap), resveratrol and proanthocyanidin (grape seed extract), Magnolia officinalis (Chinese magnolia tree), Camellia sinensis (green tea), Ginkgo biloba, quercetin, Poria cocos, Zingiber officinalis (ginger), Panax ginseng, Rabdosia rubescens hora (Rabdosia), and Chinese destagnation herbs.

S.M. Sagar et al.

Current Oncology 13 (3), 01 Jun 2006

This study measured the effects of a proprietary blend of extracts of Magnolia officinalis and Phellodendron amurense ( Relora ® ) on anxiety, stress and sleep in healthy premenopausal women.

Douglas S Kalman et al.

Nutrition Journal 7 (7), 21 Apr 2008

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