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Phosphoinositide-3-Kinase Regulatory Subunit Polypeptide 3 definition: Phosphoinositide-3-Kinase, Regulatory Subunit, Polypeptide 3, encoded by the PIK3CG gene, binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. (from Swiss-Prot)
 
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