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ATP Citrate (pro-S)-Lyase definition: An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.
citrate synthase definition: the first enzyme of the Krebs' cycle transfers the 2-carbon unit from acetyl coA to oxaloacetate, forming citrate.
Citrate (si)-Synthase definition: Enzyme that catalyzes the first step of the tricarboxylic acid cycle (CITRIC ACID CYCLE). It catalyzes the reaction of oxaloacetate and acetyl CoA to form citrate and coenzyme A. This enzyme was formerly listed as EC 4.1.3.7.
 
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