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topoisomerase II alpha definition: This gene plays a role in DNA replication, chromosome recombination and the regulation of the DNA topology during transcription. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464377&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=464377&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C26592" NCI Thesaurus)
TOP2A Gene definition: This gene plays a role in DNA replication, chromosome recombination and the regulation of DNA topology during transcription.
 
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