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Definition
 
enEnglish
Antithrombin III definition: A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
antithrombin III definition: blood glycoprotein which inhibits thrombin and other blood coagulation factors; important to maintenance of normal blood fluidity.
Factor IXa definition: Activated form of factor IX. This activation can take place via the intrinsic pathway by the action of factor XIa and calcium, or via the extrinsic pathway by the action of factor VIIa, thromboplastin, and calcium. Factor IXa serves to activate factor X to Xa by cleaving the arginyl-leucine peptide bond in factor X.
Factor Va definition: Activated form of factor V. It is an essential cofactor for the activation of prothrombin catalyzed by factor Xa.
Factor VIIa definition: Activated form of factor VII. Factor VIIa activates factor X in the extrinsic pathway of blood coagulation.
myosin definition: superfamily of proteins that function as translocating proteins the common characteristics are to bind actin and hydrolyze MgATP generally consist of heavy chains which are involved in locomotion, and light chains which are are involved in regulation superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.
Myosins definition: A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.
actin-dependent ATPase activity definition: Catalysis of the reaction: ATP + H2O = ADP + phosphate, requiring the presence of an actin filament to accelerate release of ADP and phosphate. [GOC:mah]
Activated p21cdc42Hs Kinase definition: Activated p21cdc42Hs Kinase, encoded by the ACK1 gene, is a non-receptor tyrosine kinase. It binds CDC42 in its GTP-bound activated form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of CDC42. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The encoded protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of CDC42 and which is directly linked to a tyrosine phosphorylation signal transduction pathway. (From LocusLink, OMIM and NCI)
MSC Gene definition: This gene is involved in the repression of transcription. It may also play a role in the regulation of B-cell differentiation.
7 further definitions >>
deGerman
Aktivkohle definition: [1] feinkörnige Kohle mit sehr poröser Struktur, die vor allem als Adsorptionsmittel in der Medizin und der Chemie Verwendung findet
 
Publications
 

Methods to find out the expression of activated genes

Sten Z Cekan

Reproductive biology and endocrinology : RB&E , 23 Sep 2004

Activated α4 Integrins are Preferentially Expressed on Immature Thymocytes and Activated T Cells

Fengyu Shu et al.

Developmental Immunology , 01 Jun 2002

The safety profile of drotrecogin alfa (activated)

Roberto Fumagalli et al.

Critical Care , 2007

Practical aspects of treatment with drotrecogin alfa (activated)

Luigi Camporota et al.

Critical Care , 2007

Activated protein C: cost-effective or costly?

Savtaj Singh Brar et al.

Critical Care , 2007

Acute pancreatitis: a possible role for activated protein C?

Linda Kirschenbaum et al.

Critical Care , 2005

Metal interactions with voltage- and receptor-activated ion channels.

H P Vijverberg et al.

Environmental Health Perspectives , 01 Sep 1994

Peroxisome Proliferator-Activated Receptors and Acute Lung Injury

Rosanna Di Paola et al.

PPAR Research , 2007

Peroxisome Proliferator-Activated Receptors in Lung Cancer

Venkateshwar G. Keshamouni et al.

PPAR Research , 2007

Peroxisome Proliferator-Activated Receptors in Diabetic Nephropathy

Shinji Kume et al.

PPAR Research , 2008

3068 further publications >>