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Definition
 
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alpha antiadrenergic agent definition: drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists; adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Adrenergic alpha-Antagonists definition: Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Alpha-Adrenergic Antagonist definition: Natural or synthetic Alpha-adrenergic Blocking Agents selectively bind to adrenergic receptors, or compete with natural adrenergic mediators, and inactivate alpha adrenergic receptors of the sympathetic nervous system. These agents block the action of natural sympathomimetic neurotransmitters (norepinephrine and related substances), and can initiate physiological responses such as vasodilation, bradycardia, and pupil contraction. (NCI04)
Adrenergic beta-Antagonists definition: Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Beta-Adrenergic Antagonist definition: Natural or synthetic Beta Adrenergic Blocking Agents typically bind to - but do not activate - beta-adrenergic receptors, blocking or diminishing physiologic beta-adrenergic agonist actions and activation of the sympathetic system. Reducing cardiac output, beta adrenergic antagonists are generally used for treatment of hypertension, cardiac arrythmias, angina pectoris, glaucoma, migraine headaches, and anxiety. (NCI04)
Aldosterone Antagonists definition: Compounds which inhibit or antagonize the biosynthesis or actions of aldosterone.
aldosterone inhibitor definition: agent that counteracts or opposes the action of aldosterone.
Androgen Antagonists definition: Compounds which inhibit or antagonize the biosynthesis or actions of androgens.
antiandrogens definition: (an-tee-AN-dro-jens) Drugs used to block the production or interfere with the action of male sex hormones.
androgen inhibitor definition: substance or state which suppresses, prevents, opposes or slows down the actions of the steroid hormone androgen.
48 further definitions >>
Publications
 

Why are mineralocorticoid receptor antagonists cardioprotective?

Wenxia Chai et al.

Naunyn-Schmiedeberg's Archives of Pharmacology , 01 Dec 2006

Therapeutic potential of growth factors and their antagonists.

A. Garner

The Yale Journal of Biology and Medicine , 1992

Potentiation of DNA damage and cytotoxicity by calmodulin antagonists.

S. A. Rosenthal et al.

The Yale Journal of Biology and Medicine , 1988

Current status of acid pump antagonists (reversible PPIs).

W. Wurst et al.

The Yale Journal of Biology and Medicine , 1996

Small-molecule Bcl-2 antagonists as targeted therapy in oncology

M.R. Warr et al.

Current Oncology , 01 Dec 2008

Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: A complete structure–activity profile

Barbara Cacciari et al.

Purinergic Signalling , 01 Jun 2007

Inhibition of anti-tuberculosis T-lymphocyte function with tumour necrosis factor antagonists

Haïfa Hamdi et al.

Arthritis Research & Therapy , 2006

Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor

Noel G Carlson et al.

Journal of Neuroinflammation , 17 Feb 2009

A Review of the Adverse Effects of Peripheral Alpha-1 Antagonists in Hypertension Therapy

Chris L Bryson et al.

Current Controlled Trials in Cardiovascular Medicine , 2002

New targets for therapy in breast cancer: Mammalian target of rapamycin (mTOR) antagonists

Hetty Carraway et al.

Breast Cancer Research , 2004

308 further publications >>