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Definition
 
enEnglish
Biological Availability definition: The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action.
Bioavailability definition: The rate and extent to which the active ingredient or active moiety is absorbed from a drug product and becomes available at the site of action. For drug products that are not intended to be absorbed into the bloodstream, bioavailability may be assessed by measurements intended to reflect the rate and extent to which the active ingredient or active moiety becomes available at the site of action (21CFR320.1).
Health Services Accessibility definition: The degree to which individuals are inhibited or facilitated in their ability to gain entry to and to receive care and services from the health care system. Factors influencing this ability include geographic, architectural, transportational, and financial considerations, among others.
health care service availability definition: degree to which individuals are inhibited or facilitated in their ability to gain entry to and to receive care and services from the health care system; factors influencing availability include geographic, architectural, transportational and financial considerations, among others.
Access to Care definition: The degree to which individuals are inhibited or facilitated in their ability to gain entry to and to receive care and services from the health care system. Factors influencing this ability include geographic, architectural, transportational, and financial considerations, among others.
Nutritive Value definition: An indication of the contribution of a food to the nutrient content of the diet. This value depends on the quantity of a food which is digested and absorbed and the amounts of the essential nutrients (protein, fat, carbohydrate, minerals, vitamins) which it contains. This value can be affected by soil and growing conditions, handling and storage, and processing.
nutrient bioavailability definition: extent to which nutrients become available at the site of action or the accessibility to a site of action.
Availability definition: The quality of being obtainable or accessible and ready for use or service.
BIO-AVAILABILITY definition: A study of the degree to which or rate at which a drug or other substance is absorbed or becomes available at the site of physiological activity after administration. (NCI)
Bioavailability Study definition: A study of the degree to which, or rate at which, a drug or other substance is absorbed or becomes available at the site of physiological activity after administration.
 
deGerman
Verfügbarkeit definition: [1] relative Zeitangabe, während der ein System genutzt werden kann [2] Handlungsspielraum eines Subjekts [3] Existenz und Nutzbarkeit eines Gegenstandes
 
frFrench
disponibilité definition: État d'une personne qui est disponible ; qualité d'une personne qui sait se rendre disponible.
disponibilité definition: État des fonctionnaires et des agents de toute sorte, mais en particulier des officiers de l’armée, qui ne sont pas en activité de service et restent pourtant toujours à la disposition de leurs chefs.
disponibilité definition: Sommes dont on peut disposer.
 
Examples
 

Methods A recently developed and less well-known alternative is the paired availability design for historical controls.

Stuart G Baker et al.

BMC Medical Research Methodology 1 (7), 26 Sep 2001

The paired availability design requires at least 10 hospitals or medical centers in which there is a change in the availability of the medical intervention.

Stuart G Baker et al.

BMC Medical Research Methodology 1 (7), 26 Sep 2001

The statistical analysis involves a weighted average of a simple "before" versus "after" comparison from each hospital or medical center that adjusts for the change in availability.

Stuart G Baker et al.

BMC Medical Research Methodology 1 (7), 26 Sep 2001

We expanded requirements for the paired availability design to yield valid inference. (1) The hospitals or medical centers serve a stable population. (2) Other aspects of patient management remain constant over time. (3) Criteria for outcome evaluation are constant over time. (4) Patient preferences for the medical intervention are constant over time. (5) For hospitals where the intervention was available in the "before" group, a change in availability in the "after group" does not change the effect of the intervention on outcome.

Stuart G Baker et al.

BMC Medical Research Methodology 1 (7), 26 Sep 2001

The paired availability design has promise for evaluating medical versus surgical interventions, in which it is difficult to recruit patients to a randomized trial.

Stuart G Baker et al.

BMC Medical Research Methodology 1 (7), 26 Sep 2001

1606 further examples >>
Publications
 

The Paired Availability Design for Historical Controls

Stuart G Baker et al.

BMC Medical Research Methodology , 26 Sep 2001

Comparing breast cancer mortality rates before-and-after a change in availability of screening in different regions: Extension of the paired availability design

Stuart G Baker et al.

BMC Medical Research Methodology , 18 May 2004

Quality and availability of consumer information on heart failure in Australia

Agnes I Vitry et al.

BMC Health Services Research , 12 Dec 2008

Histoplasma capsulatum proteome response to decreased iron availability

Michael S Winters et al.

Proteome Science , 24 Dec 2008

International Network for the Availability of Scientific Publications: Facilitating Scientific Publishing in Developing Countries

Pippa Smart

PLoS Biology , 01 Nov 2004

Instant availability of patient records, but diminished availability of patient information: A multi-method study of GP's use of electronic patient records

Tom Christensen et al.

BMC Medical Informatics and Decision Making , 28 Mar 2008

Elevated midbrain serotonin transporter availability in mixed mania: a case report

Tommi Tolmunen et al.

BMC Psychiatry , 13 Sep 2004

Proactively Monitoring Departmental Clinical IT Systems with an Open Source Availability System

C. Toland et al.

Journal of Digital Imaging , 01 Nov 2007

Assessing Retail Fruit and Vegetable Availability in Urban and Rural Underserved Communities

Akiko S Hosler et al.

Preventing Chronic Disease , 15 Sep 2008

Comparative indicators for cancer network management in England: Availability, characteristics and presentation

Mark McCarthy et al.

BMC Health Services Research , 27 Feb 2008

1601 further publications >>