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Amino Acids, Basic definition: Amino acids with side chains that are positively charged at physiological pH.

Substitution of basic amino acids in the basic region stabilizes DNA binding by E12 homodimers.

S J Vitola et al.

Nucleic Acids Research , 15 May 1996

Amino acid sequence of human respiratory syncytial virus nucleocapsid protein.: ... dal protein is rich in basic amino acids and has no homologies ...

N Elango et al.

Nucleic Acids Research , 10 Sep 1983

The use of histone as a facilitator to improve the efficiency of retroviral gene transfer.: ... is a transporter for basic amino acids; we therefore explored ...

D Singh et al.

Nucleic Acids Research , 01 Aug 1996

The complete sequence of RNA segment 2 of influenza A/NT/60/68 P1 protein.: ... gene product is a basic 86,300 dalton protein with a net charge at neutral pH of +23. A 29 amino acid stretch of the protein (coded by nucleotide residues 583-669) is highly basic and contains 7 lysine and 8 arginine residues. Other smaller clusters of basic amino acids are also present in the ...

D H Bishop et al.

Nucleic Acids Research , 25 Feb 1982

Physiological and chemical characterization of cyanobacterial metallothioneins.: ... of hydroxylated or basic amino acids with cysteines. ...

R W Olafson

Environmental Health Perspectives , 01 Mar 1986

The structure and expression of the preproenkephalin gene.: ... is flanked by paired basic amino acids which are presumably ...

S Legon et al.

Nucleic Acids Research , 20 Dec 1982

Molecular cloning and nucleotide sequencing of the nusB gene of E. coli.: ... 20 acidic and 21 basic amino acids. A significant promoter ...

S Ishii et al.

Nucleic Acids Research , 25 Jun 1984

Requirement of protein co-factor for the DNA-binding function of the human ski proto-oncogene product.: ... a region rich in basic amino acids. Images

T Nagase et al.

Nucleic Acids Research , 25 Jan 1990

Effects of phosphate neutralization on the shape of the AP-1 transcription factor binding site in duplex DNA.: ... charges distal to the basic region in bound bZIP proteins. The extent and direction of apparent DNA bending are consistent with the prediction that DNA will collapse locally upon asymmetric phosphate charge neutralization. To prove that asymmetric phosphate neutralization could produce the observed degree of DNA bending, the present experiments partially substitute anionic phosphate diesters in the AP-1 site with various numbers of neutral methylphosphonate linkages. DNA bending is induced toward the neutralized face of DNA. The degree of DNA bending induced by methylphosphonate substitution (approximately 3.5 degrees per neutralized phosphate) is comparable to that induced by GCN4 variants carrying increasing numbers of additional basic amino acids. It is plausible, ...

L A Tomky et al.

Nucleic Acids Research , 15 May 1998

Histone deacetylase-independent transcriptional repression by methyl-CpG-binding protein 2: ... two clusters of basic amino acids. Mutation of the first ...

Fang Yu et al.

Nucleic Acids Research , 15 May 2000

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