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Biological Markers definition: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, environmental exposure and its effects, disease diagnosis, metabolic processes, substance abuse, pregnancy, cell line development, epidemiologic studies, etc.
biomarker definition: a biological, physiological, behavioral, or molecular indicator of a process, disease, or system; e.g., fish mortality and pollution, behavioral changes and alcoholism, neuroendocrine system changes and aging.
marker definition: A diagnostic indication that disease may develop.
Biomarker definition: A characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. (From: FDA Guidance for Industry: Pharmacogenomic Data Submissions.)
Biomarker definition: A variation in cellular or biochemical components or processes, structures, or functions that is objectively measurable in a biological system and that characterizes normal biologic processes, pathogenic processes, an organism's state of health or disease, likelihood of developing a disease, prognosis, or response to a particular therapeutic intervention. Biomarkers include but not limited to such phenotypic parameters as specific enzyme or hormone concentration, specific gene phenotype, presence or absence of biological substances.
Biomarkers and Prevention Research Branch definition: The Branch plans and conducts intramural research aimed at identifying new tools for the early detection of cancers and developing cancer intervention agents. (from Division of Cancer Prevention and Control 1994 Annual Report)
Cancer Biomarkers Research Group definition: The mission of the CBRG is to engage basic and clinical scientists as well as epidemiologists and statisticians in a search for and validation of promising early cancer biomarkers. To do so, the CBRG supports and facilitates a broad spectrum of national and international research activities in molecular biology and genetics, particularly for the discovery of biomarkers for risk prediction and early detection of cancer. The CBRG also supports the development of databases and informatics systems to optimize tracking and assessment of biomarker utility and expression patterns.
Biomarkers, Pharmacological definition: Measurable biological parameters that serve for drug development, safety and dosing (DRUG MONITORING).
 
Publications
 

Biomarkers in osteoarthritis

Frances MK Williams et al.

Arthritis Research & Therapy , 2008

The cancer secretome: a reservoir of biomarkers

Hua Xue et al.

Journal of Translational Medicine , 17 Sep 2008

Nondestructive biomarkers in ecotoxicology.

M C Fossi

Environmental Health Perspectives , 01 Dec 1994

Application of molecular biomarkers in epidemiology.

M T Smith et al.

Environmental Health Perspectives , 01 Jan 1994

Biomarkers of environmental benzene exposure.

C Weisel et al.

Environmental Health Perspectives , 01 Dec 1996

Novel Biomarkers for Predicting Preeclampsia

David M. Carty et al.

Trends in Cardiovascular Medicine , 01 Jul 2008

Salivary biomarkers in psychobiological medicine

Francesco Chiappelli et al.

Bioinformation , 29 Dec 2006

Serum biomarkers in interstitial lung diseases

Argyris Tzouvelekis et al.

Respiratory Research , 2005

Biomarkers and Mechanisms of FANCD2 Function

Henning Willers et al.

Journal of Biomedicine and Biotechnology , 2008

Biomarkers in chronic adult hydrocephalus

Andrew Tarnaris et al.

Cerebrospinal Fluid Research , 04 Oct 2006

747 further publications >>