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enEnglish deGerman
1 word
constants Konstanten
2 words
rotational constants Rotationskonstanten
soil constants Bodenkennziffern
 
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Examples
 

We find that with increasing divergence time the sequence similarity decreases with respect to the human protein, but the affinities and association rate constants are conserved as predicted by the protein design algorithm, FoldX.

Christina Kiel et al.

PLoS Computational Biology 4 (12), 01 Dec 2008

In parallel we have done computer simulations on a minimal network based on Ras-effector interactions, and our results indicate that in the absence of negative feedback, changes in kinetics that result in similar binding constants have strong consequences on network behavior.

Christina Kiel et al.

PLoS Computational Biology 4 (12), 01 Dec 2008

This, together with the previous results, suggests an important biological role, not only for equilibrium binding constants but also for kinetics in signaling processes involving Ras-effector interactions.

Christina Kiel et al.

PLoS Computational Biology 4 (12), 01 Dec 2008

These kinetic rates are important for signaling; however, to what extent individual changes in such rate constants are biologically important or whether the affinity is more crucial might be different in different signaling processes.

Christina Kiel et al.

PLoS Computational Biology 4 (12), 01 Dec 2008

In the majority of the cases, affinities between proteins and protein-ligands are determined using equilibrium binding methods, like isothermal titration calorimetry and fluorescence based methods, while rate constants of association and dissociation are only rarely determined.

Christina Kiel et al.

PLoS Computational Biology 4 (12), 01 Dec 2008

431 further examples >>
Publications
 

Association Rate Constants of Ras-Effector Interactions Are Evolutionarily Conserved

Christina Kiel et al.

PLoS Computational Biology , 01 Dec 2008

The estimation of affinity constants for the binding of model peptides to DNA by equilibrium dialysis.

K C Standke et al.

Nucleic Acids Research , 01 Oct 1975

Extraction of elementary rate constants from global network analysis of E. coli central metabolism

Jiao Zhao et al.

BMC Systems Biology , 07 May 2008

Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae

Gerhard Wieland et al.

Nucleic Acids Research , 01 Mar 2001

Determination of protein–DNA binding constants and specificities from statistical analyses of single molecules: MutS–DNA interactions

Yong Yang et al.

Nucleic Acids Research , 2005

Heteronuclear NMR of DNA with the heteronucleus in natural abundance: facilitated assignment and extraction of coupling constants.

P Schmieder et al.

Nucleic Acids Research , 25 Sep 1992

A user-friendly Matlab program and GUI for the pseudorotation analysis of saturated five-membered ring systems based on scalar coupling constants

Pieter MS Hendrickx et al.

Chemistry Central Journal , 24 Oct 2008

Direct measurement via phage titre of the dissociation constants in solution of fusion phage-substrate complexes.

M R Dyson et al.

Nucleic Acids Research , 11 May 1995

Apparent association constants for E. coli ribosomal proteins S4, S7, S8, S15, S17 and S20 binding to 16S RNA.

J Schwarzbauer et al.

Nucleic Acids Research , 11 May 1981

Codeine-binding RNA aptamers and rapid determination of their binding constants using a direct coupling surface plasmon resonance assay

Maung Nyan Win et al.

Nucleic Acids Research , 01 Nov 2006

426 further publications >>