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WFDC2 Gene definition: This gene plays a putative role in epithelial host defense.
WFDC2 wt Allele definition: Human WFDC2 wild-type allele is located within 20q12-q13.2 and is approximately 12 kb in length. This allele, which encodes WAP four-disulfide core domain protein 2, is putatively involved in the innate immune response of the lung, nasal and oral epithelia. WFDC2 gene expression is up-regulated in certain cancers such as lung adenocarcinomas, pancreatic carcinomas and ovarian serous carcinomas.
 
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