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Definition
 
enEnglish
Gene Expression definition: The phenotypic manifestation of a gene or genes by the processes of GENETIC TRANSCRIPTION and GENETIC TRANSLATION.
gene expression definition: the phenotypic manifestation of a gene or genes by the processes of gene action.
gene expression definition: The process by which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. [GOC:dph, GOC:tb]
Gene Expression definition: Typically involves transcription of genetically encoded information into an intermediary message (messenger RNA) and subsequent translation into a functional protein.
Fibroblast Activation Protein, Alpha definition: Expressed in fibroblasts similar to DPP4 and DPPX, inducible Fibroblast Activation Protein-Alpha major isoform 1 (Long, 760-aa, 87.8-kD) and truncated isoform 2 (Short, 239-aa) are encoded by human FAP Gene (Peptidase S9B Family). Heterodimeric (with DPP4) or homodimeric, N-glycosylated FAPA is a type II integral membrane protein gelatinase: 13 extracellular cysteine residues and 3 conserved serine protease domains, a transmembrane segment, and a short cytoplasmic tail. Monomer is inactive. On lamellipodia, FAPA appears involved in epithelial-mesenchymal interactions during development, tissue repair/remodeling, epithelial carcinogenesis, and malignant invasion. A product of the same gene, monomeric N-glycosylated Seprase is composed of proteolytically inactive subunits whose activities depend on subunit association. (from LocusLink, Swiss-Prot, OMIM, and NCI)
Fibroblast Activation Protein, Alpha definition: An inducible cell surface glycoprotein. It is expressed on fibroblasts in many common epithelial cancers. It is a gelatinase belonging to the serine protease family. It is the target of BIBH 1 monoclonal antibody.
Expressed Emotion definition: Frequency and quality of negative emotions, e.g., anger or hostility, expressed by family members or significant others, that often lead to a high relapse rate, especially in schizophrenic patients. (APA, Thesaurus of Psychological Index Terms, 7th ed)
Expressed Sequence Tags definition: Partial cDNA (DNA, COMPLEMENTARY) sequences that are unique to the cDNAs from which they were derived.
Expressed Sequence Tag definition: Refers to Sequence Tagged Sites (EST) that are represented in mRNA. They are derived as 300-500 bp single-pass mRNA sequence reads from many of the genes expressed in a given tissue and/or at a given developmental stage. They represent a snapshot of gene expression in a given place or time.
Protein Expression definition: The biosynthesis of new (often sets of distinct, functionally related) protein products, usually involving new mRNA transcripts, typically in response to an activating stimulus.
8 further definitions >>
Publications
 

Accessibility of expressed and non-expressed genes to a restriction nuclease.

W Pfeiffer et al.

Nucleic Acids Research , 24 Oct 1980

Interclonal variation in methylation patterns for expressed and non-expressed genes.

R J Shmookler Reis et al.

Nucleic Acids Research , 24 Jul 1982

Poly A- Transcripts Expressed in HeLa Cells

Qingfa Wu et al.

PLoS ONE , 30 Jul 2008

DNAase I sensitivity of genes expressed during myogenesis.

Y Carmon et al.

Nucleic Acids Research , 25 May 1982

Identification of differentially expressed genes in carp rods and cones

Yoshie Shimauchi-Matsukawa et al.

Molecular Vision , 26 Feb 2008

Multivariate search for differentially expressed gene combinations

Yuanhui Xiao et al.

BMC Bioinformatics , 26 Oct 2004

Efficacy of SSH PCR in isolating differentially expressed genes

Wan Ji et al.

BMC Genomics , 20 May 2002

Xenopus homeobox-containing cDNAs expressed in early development.

A Fritz et al.

Nucleic Acids Research , 25 Feb 1988

A Population Proportion approach for ranking differentially expressed genes

Mugdha Gadgil

BMC Bioinformatics , 18 Sep 2008

Highly expressed and alien genes of the Synechocystis genome

Jan Mrázek et al.

Nucleic Acids Research , 01 Apr 2001

7670 further publications >>