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Translation
 
enEnglish deGerman
1 word
modulator Modulator
modulator Regler
modulator Regulator
 
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deGerman enEnglish
1 word
Modulator modulator
2 words
Modem (Modulator/Demodulator) modem
 
Definition
 
enEnglish
Cyclic AMP Response Element Modulator definition: Cyclic AMP response element modulator is a basic leucine zipper transcription factor that is regulated by CYCLIC AMP. It plays an important role in SPERMATID development in the mammalian TESTIS.
GEM 91 definition: A 25-mer antisense oligodeoxynucleotide phosphorothioate. GEM-91 is complementary to the gag mRNA of human immunodeficiency virus type 1 (HIV-1), resulting in HIV-1 replication inhibition. (NCI)
chemosensitizer definition: A drug that makes tumor cells more sensitive to the effects of chemotherapy.
chemosensitizing agent definition: agent that acts to increase the sensitivity of an organism, tissue, or cell to a chemical compound.
GEM 132 definition: A 20-mer mixed backbone oligonucleotide exhibiting anti-viral activity. GEM-132 is comprised of a strand of synthetic DNA with a modified RNA at each end (2-O-methylribonucleosides at the two 3- and four 5-terminal nucleotides) which is complementary to the intron-exon boundary of the UL35 and UL37 pre-mRNA transcripts of human cytomegalovirus. (NCI)
GEM 231 definition: A drug that may inhibit the growth of malignant tumors.
GEM 231 definition: A mixed backbone oligonucleotide exhibiting antitumor activity. GEM-231 is complementary to the RI alpha subunit of Protein Kinase A (PKA), resulting in downregulation of PKA expression and ultimately tumor growth. (NCI)
selective estrogen receptor modulator definition: (sel-EK-tiv ESS-tro-jen re-SEP-tor MOD-yew-lay-tor) SERM. A drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues. Tamoxifen and raloxifene are SERMs.
selective estrogen receptor modulator definition: Selective estrogen receptor modulator. A drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues. Tamoxifen and raloxifene are SERMs.
Selective Estrogen Receptor Modulators definition: A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
14 further definitions >>
Publications
 

Modulator Property of the Intrinsic Cortical Projection from Layer 6 to Layer 4

Charles C. Lee et al.

Frontiers in Systems Neuroscience , 26 Feb 2009

The Development of INT131 as a Selective PPAR γ Modulator: Approach to a Safer Insulin Sensitizer

Linda S. Higgins et al.

PPAR Research , 2008

A Novel Secretion Pathway of Salmonella enterica Acts as an Antivirulence Modulator during Salmonellosis

Ohad Gal-Mor et al.

PLoS Pathogens , 01 Apr 2008

Deoxyribonuclease II as a probe to sequence-specific chromatin organization: preferential cleavage in the 72 bp modulator sequence of SV40 minichromosome.

A N Shakhov et al.

Nucleic Acids Research , 10 Jul 1982

WDR55 Is a Nucleolar Modulator of Ribosomal RNA Synthesis, Cell Cycle Progression, and Teleost Organ Development

Norimasa Iwanami et al.

PLoS Genetics , 01 Aug 2008

A set of genes previously implicated in the hypoxia response might be an important modulator in the rat ear tissue response to mechanical stretch

Vishal Saxena et al.

BMC Genomics , 23 Nov 2007

Signature-Based Small Molecule Screening Identifies Cytosine Arabinoside as an EWS/FLI Modulator in Ewing Sarcoma

Kimberly Stegmaier et al.

PLoS Medicine , 01 Apr 2007

Fibroin-modulator-binding protein-1 (FMBP-1) contains a novel DNA-binding domain, repeats of the score and three amino acid peptide (STP), conserved from Caenorhabditis elegans to humans

Shigeharu Takiya et al.

Nucleic Acids Research , 2005

Mactinin: a modulator of the monocyte response to inflammation

Sharon D Luikart et al.

Arthritis Research & Therapy , 2003

BP1 is a negative modulator of definitive erythropoiesis

Marthe-Sandrine Eiymo Mwa Mpollo et al.

Nucleic Acids Research , 01 Oct 2006

184 further publications >>