dict.md logo
Choose languages of interest
SELECT >>
English
German
Advertisement:
Translation
 
enEnglish deGerman
1 word
moiety Hälfte
 
Advertisement:
 
Definition
 
enEnglish
Interferon Alfa-2b definition: A recombinant alfa interferon consisting of 165 amino acid residues with arginine in position 23 and histidine in position 34. It is used extensively as an antiviral and antineoplastic agent.
recombinant interferon alfa-2b definition: A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=462279&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=462279&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1953" NCI Thesaurus)
recombinant interferon alfa-2b definition: A non-glycosylated recombinant interferon alpha, subtype 2b, used as an antiviral and antineoplastic agent. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=448847&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=448847&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1953" NCI Thesaurus)
Recombinant Interferon Alfa-2b definition: A non-glycosylated recombinant interferon with antiviral and antineoplastic activities. Alfa interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose protein products mediate antiviral, antiproliferative, anticancer, and immune-modulating effects.
interferon gamma definition: activates NK cells, cytotoxic T cells, endothelial cells, and macrophages; stimulates LAK activity; costimulates B cell proliferation; inhibits T cell proliferation; implicated in aberrant expression of MHC II antigens leading to autoimmune disease.
Interferon-gamma definition: The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES.
interferon gamma definition: A recombinant therapeutic agent which is chemically identical to or similar to the endogenous lymphokine interferon gamma (IFN-gamma) with antineoplastic, immunoregulatory, and antiviral activities. Therapeutic IFN-gamma binds to and activates the cell-surface IFN-gamma receptor, stimulating antibody-dependent cytotoxicity and enhances natural killer cell attachment to tumor cells. This agent also activates caspases, thereby inducing apoptosis in malignant cells. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40469&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40469&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C583" NCI Thesaurus)
Interferon Gamma definition: The gamma or immune IFNs are produced by T lymphocytes in response to mitogens or to antigens to which they are sensitized. They are acid-labile and serologically distinct from alpha- and beta-IFNs. (from OMIM 147570)
Interferon Gamma definition: Interferon gamma (IFNg) is produced by activated T cells and is an important immunoregulatory molecule, particularly in allergic diseases.
Tissue Plasminogen Activator definition: A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
24 further definitions >>
Publications
 

Purification of attachment moiety: a review.

I. Kahane

The Yale Journal of Biology and Medicine , 1983

Is the bithiazole moiety of bleomycin a classical intercalator?

J P Hénichart et al.

Nucleic Acids Research , 25 Sep 1985

Solution structure of a DNA duplex with a chiral alkyl phosphonate moiety

R. Soliva et al.

Nucleic Acids Research , 15 Jul 2001

Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues.

A Ciucci et al.

Nucleic Acids Research , 15 Jan 1996

Pelvo-ureteric junction obstruction in the lower pole moiety of a duplex kidney with an associated intraparenchymal abscess: a case report

James Lenton et al.

Journal of Medical Case Reports , 24 Jul 2008

Linkers designed to intercalate the double helix greatly facilitate DNA alkylation by triplex-forming oligonucleotides carrying a cyclopropapyrroloindole reactive moiety.

R O Dempcy et al.

Nucleic Acids Research , 15 Jul 1999

Clustering of RNA polymerase B molecules in the 5' moiety of the adult beta-globin gene of hen erythrocytes.

P Gariglio et al.

Nucleic Acids Research , 11 Jun 1981

Insights into spatial configuration of a galactosylated epitope required to trigger arthritogenic T-cell receptors specific for the sugar moiety

Simon Glatigny et al.

Arthritis Research & Therapy , 2007

RNA aptamers to the adenosine moiety of S-adenosyl methionine: structural inferences from variations on a theme and the reproducibility of SELEX.

D H Burke et al.

Nucleic Acids Research , 15 May 1997

An intact ribose moiety at A2602 of 23S rRNA is key to trigger peptidyl-tRNA hydrolysis during translation termination

Melanie Amort et al.

Nucleic Acids Research , 01 Aug 2007

406 further publications >>