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Translation
 
enEnglish deGerman
1 word
optimum Bestwert
optimum Optimum
optimum optimal
2 words
optimum performance optimale Leistung
 
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enEnglish frFrench
1 word
optimum optimum
 
frFrench enEnglish
1 word
optimum best
optimum optimum
 
frFrench elGreek
1 word
optimum βέλτιστος
 
deGerman enEnglish
1 word
Optimum optimum
optimum optimal
 
Definition
 
enEnglish
Acid Phosphatase definition: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.2.
Alkaline Phosphatase definition: An enzyme that catalyzes the conversion of an orthophosphoric monoester and water to an alcohol and orthophosphate. EC 3.1.3.1.
ALKALINE PHOSPHATASE definition: A leukocyte alkaline phosphatase test is a device used to identify the enzyme leukocyte alkaline phosphatase in neutrophilic granulocytes (granular leukocytes stainable by neutral dyes). The cytochemical identification of alkaline phosphatase depends on the formation of blue granules in cells containing alkaline phosphatase. The results of this test are used to differentiate chronic granulocytic leukemia (a malignant disease characterized by excessive overgrowth of granulocytes in the bone marrow) and reactions that resemble true leukemia, such as those occuring in severe infections and polycythemia (increased total red cell mass).
Alkaline Phosphatase definition: An enzyme that catalyses the cleavage of inorganic phosphate non-specifically from a wide variety of phosphate esters and having a high (greater than 8) pH optimum.
acid phosphatase activity definition: Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum. [EC:3.1.3.2]
alkaline phosphatase activity definition: Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum. [EC:3.1.3.1]
Optimum definition: The best or most suitable; the greatest degree attainable.
 
frFrench
optimum definition: La plus favorable des options, le choix le plus favorable étant donné les circonstances.
 
Examples
 

2009 A new monotonicity-constrained maximum likelihood approach, called Partial Order Optimum Likelihood (POOL), is presented and applied to the problem of functional site prediction in protein 3D structures, an important current challenge in genomics.

Wenxu Tong et al.

PLoS Computational Biology 5 (1), 01 Jan 2009

A new machine learning approach called Partial Order Optimum Likelihood (POOL) is introduced here.

Wenxu Tong et al.

PLoS Computational Biology 5 (1), 01 Jan 2009

The purpose of the present paper is five-fold: (1) We present a monotonicity-constrained maximum likelihood approach, called Partial Order Optimum Likelihood (POOL), to improve performance and expand the capabilities of active site prediction. (2) Then it is shown that POOL, with THEMATICS input data alone, outperforms previous statistical [4] and Support Vector Machine (SVM) [5] implementations of THEMATICS when applied to a test set of annotated protein structures. (3) It is then demonstrated that the inclusion of one additional 3D-structure-based feature, representing the ordinal size of the surface cleft to which each residue belongs, can result in some improved performance, as demonstrated by ROC curves and validated by Wilcoxon signed-rank tests. (4) With the introduction of environment features, POOL then can use the THEMATICS data to predict both ionizable and non-ionizable residues.

Wenxu Tong et al.

PLoS Computational Biology 5 (1), 01 Jan 2009

Furthermore, by rescaling coordinates in the primal problem, its contours become circular and the negative gradient at any point points toward a single point, the unconstrained optimum. (Thus another formulation of the primal problem is to find the point in the feasible region closest to the unconstrained optimum.) As a consequence, the active set so determined at any feasible point is exactly the same as the active set at the solution point.

Wenxu Tong et al.

PLoS Computational Biology 5 (1), 01 Jan 2009

We have audited the senior author's results over the last ten years to identify the extent of the problem, and designed a simple bench-testing of catheters of different lengths, draining at different pressure heads and with different vertical drops, in an attempt to ascertain the optimum catheter placement and length that might reduce the occurrence of low pressure headaches.

Roger Strachan et al.

Cerebrospinal Fluid Research 3 (Suppl 1), 21 Dez 2006

288 further examples >>
Publications
 

On the Optimum Sampling Time for the Measurement of Pollutants in Ambient Air

Richard J. C. Brown et al.

Journal of Automated Methods and Management in Chemistry , 2008

Partial Order Optimum Likelihood (POOL): Maximum Likelihood Prediction of Protein Active Site Residues Using 3D Structure and Sequence Properties

Wenxu Tong et al.

PLoS Computational Biology , 01 Jan 2009

Colchicine in acute gouty arthritis: the optimum dose?

George I Varughese et al.

Arthritis Research & Therapy , 2006

Optimum sedation and analgesia in critical illness: we need to keep trying

Gavin G Lavery

Critical Care , 2004

Lumbo-peritoneal shunting for idiopathic intracranial hypertension: what is the optimum catheter length and placement to avoid low-pressure headaches?

Roger Strachan et al.

Cerebrospinal Fluid Research , 21 Dec 2006

Debate: "How low should LDL cholesterol be lowered for optimum prevention of vascular disease?" Viewpoint: "Below 100 mg/dl"

W Virgil Brown

Current Controlled Trials in Cardiovascular Medicine , 2001

Optimum conditions for selective isolation of genes from complex genomes by transformation-associated recombination cloning

Sun-Hee Leem et al.

Nucleic Acids Research , 15 Mar 2003

Different deoxyribonucleases in human lymphocytes: ... the other having pH optimum of about pH 9.0, ...

E.Jürgen Zöllner et al.

Nucleic Acids Research , 01 Aug 1974

polA6, A mutation affecting the DNA binding capacity of DNA polymerase I.: ... has an altered pH optimum for polymerization and ...

W S Kelly et al.

Nucleic Acids Research , 01 Nov 1976

Individual freedom versus collective responsibility: an economic epidemiology perspective: ... do not guarantee social optimum since individuals' ...

M Zia Sadique

Emerging Themes in Epidemiology , 26 Sep 2006

283 further publications >>