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Definition
 
enEnglish
Amdinocillin definition: Amidinopenicillanic acid derivative with broad spectrum antibacterial action. It is poorly absorbed if given orally and is used in urinary infections and typhus.
Amdinocillin definition: A semisynthetic, broad spectrum beta-lactam penicillin with antibacterial activity. Amdinocillin specifically binds to and inactivates penicillin-binding protein 2 (PBP 2) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. Given the fact that most beta-lactam penicillins bind almost exclusively to PBPs 1 and 3, amdinocillin is able to synergize with other penicillins in the treatment against bacterial infections.
Ampicillin definition: Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
ampicillin definition: semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Ampicillin definition: A broad-spectrum, semi-synthetic, beta-lactam penicillin antibiotic with bactericidal activity. Ampicillin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. Ampicillin is stable against hydrolysis by a variety of beta-lactamases, therefore, can be used in wide range of gram-positive and -negative infections.
Carbenicillin definition: Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Carbenicillin definition: A broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Carbenicillin acylates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis.
Methicillin definition: One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
methicillin definition: semisynthetic penicillin used as an antibacterial in resistant staphylococcal infections.
Methicillin definition: A semisynthetic, narrow spectrum beta-lactamase-resistant penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial lysis.
25 further definitions >>
deGerman
Penizillin definition: [1] eines der ältesten Antibiotika
 
frFrench
pénicilline definition: Antibiotique bêta-lactamine, toxine provenant de la moisissure pénicillium du champignon ''Penicillium notatum'' et qui est inoffensive pour l'homme.
 
Publications
 

Ampicillin Vs. Penicillin for In Utero Therapy

Douglas D. Glover et al.

Infectious Diseases in Obstetrics and Gynecology , 1996

Intravenous Penicillin for Antenatal Syphilotherapy

Henry L. Galan et al.

Infectious Diseases in Obstetrics and Gynecology , 1993

John F. Fulton, Coccidioidomycosis, and Penicillin

Morris Tager

The Yale Journal of Biology and Medicine , 01 Sep 1976

Efficacy of Targeted 5-day Combined Parenteral and Intramammary Treatment of Clinical Mastitis Caused by Penicillin-Susceptible or Penicillin-Resistant Staphylococcus aureus

S Taponen et al.

Acta Veterinaria Scandinavica , 2003

Penicillin

Alexander Fleming

The Ulster Medical Journal , 01 Nov 1944

The Association of Viral Activation with Penicillin Toxicity in Guinea Pigs and Hamsters 1

Robert H. Green

The Yale Journal of Biology and Medicine , 01 Sep 1974

Hydrogel coated monoliths for enzymatic hydrolysis of penicillin G

K. M. de Lathouder et al.

Journal of Industrial Microbiology & Biotechnology , 01 Aug 2008

2D NMR Methods for Structural Delineation of Copper(II) Complexes of Penicillin and Pilocarpine

Elena Gaggelli et al.

Metal-Based Drugs , 1994

Optimization of culture conditions to obtain maximal growth of penicillin-resistant Streptococcus pneumoniae

Andrea V Restrepo et al.

BMC Microbiology , 02 Jun 2005

Penicillin acylase from E. coli: unique gene-protein relation.

G Schumacher et al.

Nucleic Acids Research , 25 Jul 1986

130 further publications >>