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Propofol definition: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol definition: A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=461189&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=461189&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C29384" NCI Thesaurus)
Propofol definition: A hypnotic alkylphenol derivative. Formulated for intravenous induction of sedation and hypnosis during anesthesia, propofol facilitates inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). This agent is associated with minimal respiratory depression and has a short half-life with a duration of action of 2 to 10 minutes.
 
Publications
 

Anticancer properties of propofol-docosahexaenoate and propofol-eicosapentaenoate on breast cancer cells

Rafat A Siddiqui et al.

Breast Cancer Research , 2005

Propofol Sedation for Oesophago-Gastro-Duodenoscopy

J. M. Watt et al.

Diagnostic and Therapeutic Endoscopy , 1999

The Effect of Propofol on the Canine Sphincter of Oddi

T. H. Baron et al.

HPB Surgery , 1994

Simulation of propofol anaesthesia for intracranial decompression using brain hypothermia treatment

Lu Gaohua et al.

Theoretical Biology & Medical Modelling , 29 Nov 2007

Human physiologically based pharmacokinetic model for propofol

David G Levitt et al.

BMC Anesthesiology , 22 Apr 2005

The Influence of Injection Rate on the Hypnotic Effect of Propofol during Anesthesia: A Randomized Trial

Jasmin Blum et al.

PLoS Clinical Trials , 28 Jul 2006

Effect of propofol and etomidate on normoxic and chronically hypoxic pulmonary artery

Nazinigouba Ouédraogo et al.

BMC Anesthesiology , 03 Mar 2006

Propofol lipidic infusion promotes resistance to antifungals by reducing drug input into the fungal cell

Sofia Costa-de-Oliveira et al.

BMC Microbiology , 17 Jan 2008

Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA A receptor chloride channels

Shui-Wang Ying et al.

Molecular Pain , 14 Jan 2005

Protective activity of propofol, Diprivan and intralipid against active oxygen species.

M Mathy-Hartert et al.

Mediators of Inflammation , 1998

26 further publications >>