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Translation
 
enEnglish deGerman
1 word
pyruvate Pyruvat
 
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enEnglish frFrench
1 word
pyruvate pyruvate
 
enEnglish itItalian
1 word
pyruvate piruvato
 
frFrench enEnglish
1 word
pyruvate pyruvate
 
frFrench deGerman
1 word
pyruvate Pyruvat
 
frFrench itItalian
1 word
pyruvate piruvato
 
Definition
 
enEnglish
Acetolactate Synthase definition: A flavoprotein enzyme that catalyzes the formation of acetolactate from 2 moles of PYRUVATE in the biosynthesis of VALINE and the formation of acetohydroxybutyrate from pyruvate and alpha-ketobutyrate in the biosynthesis of ISOLEUCINE. This enzyme was formerly listed as EC 4.1.3.18.
Pyruvate Carboxylase definition: A biotin-dependent enzyme belonging to the ligase family that catalyzes the addition of CARBON DIOXIDE to pyruvate. It is occurs in both plants and animals. Deficiency of this enzyme causes severe psychomotor retardation and ACIDOSIS, LACTIC in infants. EC 6.4.1.1.
Pyruvate Carboxylase Deficiency Disease definition: An autosomal recessive metabolic disorder caused by absent or decreased PYRUVATE CARBOXYLASE activity, the enzyme that regulates gluconeogenesis, lipogenesis, and neurotransmitter synthesis. Clinical manifestations include lactic acidosis, seizures, respiratory distress, marked psychomotor delay, periodic HYPOGLYCEMIA, and hypotonia. The clinical course may be similar to LEIGH DISEASE. (From Am J Hum Genet 1998 Jun;62(6):1312-9)
Pyruvate Decarboxylase definition: Catalyzes the decarboxylation of an alpha keto acid to an aldehyde and carbon dioxide. Thiamine pyrophosphate is an essential cofactor. In lower organisms, which ferment glucose to ethanol and carbon dioxide, the enzyme irreversibly decarboxylates pyruvate to acetaldehyde. EC 4.1.1.1.
pyruvate decarboxylase definition: also another name for EC 1.2.4.1, PYRUVATE DEHYDROGENASE, do not confuse.
pyruvate dehydrogenase definition: a component of the multi-enzyme pyruvate dehydrogenase complex also another name for EC 4.1.1.1, PYRUVATE DECARBOXYLASE, do not confuse.
Pyruvate Dehydrogenase Complex definition: A multienzyme complex responsible for the formation of ACETYL COENZYME A from pyruvate. The enzyme components are PYRUVATE DEHYDROGENASE (LIPOAMIDE); dihydrolipoamide acetyltransferase; and LIPOAMIDE DEHYDROGENASE. Pyruvate dehydrogenase complex is subject to three types of control: inhibited by acetyl-CoA and NADH; influenced by the energy state of the cell; and inhibited when a specific serine residue in the pyruvate decarboxylase is phosphorylated by ATP. PYRUVATE DEHYDROGENASE (LIPOAMIDE)-PHOSPHATASE catalyzes reactivation of the complex. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Pyruvate Kinase definition: ATP:pyruvate 2-O-phosphotransferase. A phosphotransferase that catalyzes reversibly the phosphorylation of pyruvate to phosphoenolpyruvate in the presence of ATP. It has four isozymes (L, R, M1, and M2). Deficiency of the enzyme results in hemolytic anemia. EC 2.7.1.40.
Pyruvate, Orthophosphate Dikinase definition: An enzyme that catalyzes the reaction of ATP, pyruvate, and orthophosphate to form AMP plus phosphoenolpyruvate plus pyrophosphate. EC 2.7.9.1.
beta-Alanine-Pyruvate Transaminase definition: A PYRIDOXAL PHOSPHATE containing enzyme that catalyzes the transfer of an amino group from L-ALANINE to 3-oxopropanoate to generate PYRUVATE and BETA-ALANINE.
14 further definitions >>
deGerman
Pyruvat definition: [1] Chemie: Salz, welches das Anion der Brenztraubensäure enthält
 
Publications
 

Effects of arsenic on pyruvate dehydrogenase activation.

C M Schiller et al.

Environmental Health Perspectives , 01 Aug 1977

Bench-to-bedside review: Amelioration of acute renal impairment using ethyl pyruvate

Michael C Reade et al.

Critical Care , 2005

Nucleotide sequence of the pyruvate decarboxylase gene from Zymomonas mobilis.

A D Neale et al.

Nucleic Acids Research , 25 Feb 1987

Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum

Judith Becker et al.

Microbial Cell Factories , 13 Mar 2008

Cloning of cDNA for pyruvate, Pi dikinase from maize leaves.

D R Hague et al.

Nucleic Acids Research , 25 Jul 1983

Crystallization and preliminary X-ray diffraction analysis of ω-amino acid:pyruvate transaminase from Chromobacterium violaceum

Christopher Sayer et al.

Acta Crystallographica Section F: Structural Biology and Crystallization Communications , 17 Jan 2007

Oral Tolerance and Pyruvate Dehydrogenase in Patients with Primary Biliary Cirrhosis

Ayako Suzuki et al.

Developmental Immunology , 01 Jun 2002

Expression of Pyruvate Carboxylase mRNA Variants in Liver of Dairy Cattle at Calving

Cansu Agca et al.

PLoS ONE , 05 Dec 2007

The effects of creatine pyruvate and creatine citrate on performance during high intensity exercise

Ralf Jäger et al.

Journal of the International Society of Sports Nutrition , 13 Feb 2008

Metabolic compartmentalization in the human cortex and hippocampus: evidence for a cell- and region-specific localization of lactate dehydrogenase 5 and pyruvate dehydrogenase

Jocelyn D Laughton et al.

BMC Neuroscience , 23 May 2007

94 further publications >>