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Translation
 
enEnglish deGerman
1 word
receptors Rezeptoren
2 words
alpha receptors Alpha-Rezeptoren
 
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Definition
 
enEnglish
Receptors, Purinergic P1 definition: A class of cell surface receptors that prefers ADENOSINE to other endogenous purines. Purinergic P1 receptors are widespread in the body including the cardiovascular, respiratory, immune, and nervous systems. There are at least two pharmacologically distinguishable types (A1 and A2, or Ri and Ra). The methylxanthines, e.g., CAFFEINE, bind to these receptors, but also have other unrelated effects.
Adenosine Receptor definition: One of the purinergic P1 receptors that prefers adenosine to other endogenous purines.
Adenosine Receptor definition: The three conserved (GPCR Family) widely expressed types of Adenosine Receptors (A1, A2, A3) exhibit specific patterns of ligand binding and unique tissue distributions. Each cell-surface integral membrane protein receptor contains a 7 transmembrane domain and interacts with a heterotrimeric G protein complex in response to adenosine ligand to stimulate or suppress cAMP accumulation through adenylate cyclase activation or inhibition. Regulating diverse physiologic functions (cardiac rate and contractility, smooth muscle tone, sedation, release of neurotransmitters, platelet function, lipolysis, renal function, white blood cell function, and spermatozoal capacitation), adenosine receptors modulate the activity of neuronal populations, platelets, neutrophils, and mast cells, and smooth muscle cells in bronchi and vasculature. A potent biologic mediator, most effects of adenosine protect cells during stress.
Purinergic P1 Receptor definition: Cell surface receptors that bind to adenosine. These receptors have an enhanced affinity for adenosine and preferentially bind to this nucleoside compared to other purine moieties present within the body. Two types of receptors, termed A1 and A2, have been identified and they are both widely expressed in the body.
Receptors, Adrenergic, alpha-2 definition: A subclass of alpha-adrenergic receptors (RECEPTORS, ADRENERGIC, ALPHA). alpha-2 Adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist clonidine and the antagonist yohimbine. They are found on pancreatic beta cells, platelets, and VASCULAR SMOOTH MUSCLE, as well as both pre- and postsynaptically in the central and peripheral nervous systems.
Receptors, Adrenergic definition: Cell-surface proteins that bind epinephrine and/or norepinephrine with high affinity and trigger intracellular changes. The two major classes of adrenergic receptors, alpha and beta, were originally discriminated based on their cellular actions but now are distinguished by their relative affinity for characteristic synthetic ligands. Adrenergic receptors may also be classified according to the subtypes of G-proteins with which they bind; this scheme does not respect the alpha-beta distinction.
adrenergic receptor definition: family of G protein coupled receptors sensitive to epinephrine, norepinephrine, and their analogs, found in smooth and cardiac muscle, autonomic ganglia, brain, and elsewhere.
Receptors, Androgen definition: Proteins, generally found in the CYTOPLASM, that specifically bind ANDROGENS and mediate their cellular actions. The complex of the androgen and receptor migrates to the CELL NUCLEUS where it induces transcription of specific segments of DNA.
androgen receptor definition: proteins, generally found in the cytoplasm, that specifically bind androgens and mediate their cellular actions.
Receptors, Angiotensin definition: Cell surface proteins that bind ANGIOTENSINS and trigger intracellular changes influencing the behavior of cells.
48 further definitions >>
Publications
 

P2Y receptors and pain transmission

Zoltan Gerevich et al.

Purinergic Signalling , 01 Dec 2004

P2 receptors and chronic pain

Kazuhide Inoue

Purinergic Signalling , 01 Mar 2007

Toll-like receptors: a family of pattern-recognition receptors in mammals

Myriam A Armant et al.

Genome Biology , 2002

Hot receptors in the brain

Hendrik W Steenland et al.

Molecular Pain , 08 Nov 2006

P1 receptors and cytokine secretion

Maria P. Abbracchio et al.

Purinergic Signalling , 01 Mar 2007

Estrogen receptors and breast cancer.

R I Nicholson et al.

Environmental Health Perspectives , 01 Apr 1981

Internalization and desensitization of adenosine receptors

Elisabeth C. Klaasse et al.

Purinergic Signalling , 01 Mar 2008

The fate of P2Y-related orphan receptors: GPR80/99 and GPR91 are receptors of dicarboxylic acids

Nathalie Suarez Gonzalez et al.

Purinergic Signalling , 01 Dec 2004

Role of retinoic receptors in lung carcinogenesis

Krisztina Bogos et al.

Journal of Experimental & Clinical Cancer Research : CR , 14 Jul 2008

Predicting the Receptive Range of Olfactory Receptors

Rafi Haddad et al.

PLoS Computational Biology , 01 Feb 2008

2638 further publications >>